Researchers look into components of RNA silencing machinery
...rson's DNA is believed to be junk DNA. In order to prevent these relics of evolution from rearranging chromosomes and causing disease, natural mechanisms exist to silence them, according to contemporary theories of chromosome biology. The RNA silencing machinery silences gene expression, by destroying RNA...Cutting-edge cancer researchers sought for international recognition
... landmark achievements in the continuing effort to prevent and cure cancer. The dynamic lectures given during the AACR Annual Meeting are the perfect forum for promoting and rewarding outstanding cancer research and for motivating cancer investigators around the world. The Kirk A. and Dorothy P. Landon Found...Good bacteria trigger proteins to protect the gut
...actice of giving antibiotics to cancer patients to prevent infections might render the gut more vulnerable to...rointestinal system. And they produce factors that prevent colonization by pathogenic bacteria. Our work, however, has revealed a role that is quite different....Scientists discover new intricacies in how ulcer bugs stick to stomach
...h lining, we may be able to develop better ways to prevent or decrease infections," says Douglas E. Berg, Ph.... approaches to blocking adhesion we may be able to prevent infection," Berg says. "It's possible, though, that we may have to set our sights on decreasing the ......sed organohalogens, which repel predatory fish and prevent bacterial overgrowth, he says. These compounds are being studied to someday prevent barnacle growth on the underside of ships. Several other marine organohalogens have promising medici...Joslin Diabetes Center releases new low impact exercise video
... Exercise is an important way to delay or prevent the onset of type 2 diabetes as well as to improve...tes. "Physical limitations often prevent many people who want to improve their fitness from doing so, but these limitations do not need to st...Study yields insights into precancerous condition
..."We knew that the drug rapamycin [commonly used to prevent newly transplanted organs from being rejected] could block mTOR," says Cantley. "These new results suggest that the use of mTOR inhibitors, including rapamycin analogs currently being tested in clinical trials for the treatment of cancers and tuberou...LSU vet school professor uses gene therapy to destroy cancerous tumors
...e-injection method is to attack smaller tumors and prevent their recurrence. In addition to these methods, Li is researching a form of electrochemogene therapy. While younger, stronger immune systems may benefit from the electroporation immunogene therapy by itself, older, weaker immune systems may still r...Molecular motor shuttles key protein in response to light
... swift relocation, the researchers proposed, helps prevent temporary blindness that would otherwise be caused by a sudden increase in light intensity, such as occurs when stepping from a dark movie theater into the bright afternoon sunshine. "We knew that arrestin was transported, but we didn't know how thi...Gene expression patterns may help predict risk and progression of prostate cancer
...ase to progress and develop therapeutic targets to prevent its progression at an earlier stage." In the study, Dr. Luo, also director of the gene array laboratory at the University of Pittsburgh, and colleagues used high throughput quantitative analysis to genetically profile prostate cancer tissue an...Tips from the Journals of the American Society for Microbiology
...201 should be further investigated as a vaccine to prevent human brucellosis." (M.J. Izadjoo, A.K. Bhattacharjee, C.M. Paranavitana, T.L. Hadfield, D.L. Hoover. 2004. Oral vaccination with Brucella melitensis WR201 protects mice against intranasal challenge with virulent Brucella melitensis 16M. In...JCI Table of Contents, 15 July 2004
... member that is bone sparing and therefore able to prevent bone-loss in patients undergoing HAART, and the sp...use with the mutant genetic background, they could prevent disease formation. All of these data show that it is not the presence of a mutated protein that cau...Acamprosate: potential medication for treating alcoholism
...te is a medication used in Europe and elsewhere to prevent relapse in alcoholics. New findings, in conjunctio...ate), a medication used in Europe and elsewhere to prevent relapse in alcoholics, and currently under review for use by the U.S. Food and Drug Administration. ...Mouse brain stem cells capable of converting into blood vessel cells
... different organs one day may be harnessed to help prevent and treat neurological disorders." In their experiments, Gage and his colleagues grew mouse brain stem cells, which form neurons and glial cells, in the same culture dishes with human endothelial cells, which form the lining of blood vessels. Over ti...Findings suggest need for new view of p53 cancer protein's interaction with DNA
...mportant structural difference in Cep-1 that would prevent it from binding to its DNA sequence in the same way p53 has been shown to do to its. At first glance, these results would seem to be more confusing than helpful. Halazonetis believes, however, that resolution of the apparent conflict lies in remembe...New research suggests previously unrecognized mechanism by which blood vessels are patterned
...he groundwork for discovering ways to diagnose and prevent CHD. In an accompanying article in Developmental Cell, Epstein and collaborators at the National Institutes of Health demonstrated the pathways that they have discovered are functional in diverse organisms, including fish. In the larger picture, th...Secret behind hard exoskeletons, spreading wings revealed
...re treated shortly after they leave their pupae to prevent them from releasing their own bursicon will harden...y mutants into blow flies that had been treated to prevent bursicon release. The shells of the blow flies did not harden nor darken after the injection as they...Report outlines steps needed to lessen smallpox threat
...gents." Given the pressing need for novel drugs to prevent the spread of smallpox if it were to be used as a bioterror agent, Harrison said that the group's top recommendation was the immediate engagement of biotechnology and pharmaceutical companies in the project. With the estimated price tag for developin...Triple-vaccine strategy stimulates strong HIV-specific immune response in monkeys
...studies to reduce viral load, although they do not prevent infection. The new vaccine regimen we tested induced unprecedented levels of CD8+ T cells in monkeys." The experimental vaccines developed by Ertl and her colleagues take advantage of sophisticated bioengineering technologies and the special characte......ic instructions - which can render RNA useless and prevent it from creating more proteins. The two substances were tested in an animal model, in which human foreskin was infected with HPV 11, and then grafted onto immunodeficient mice. Five of 11 grafts treated with ASO407 showed eradication of the virus. Of...