Brain Protein "Rescues" Neurons From Atrophy
...mally. Importantly, atrophy of the neurons was not prevented by other neurotrophins, called BDNF, NT-3 or NGF, the scientists reported. This specificity showed that NT-4 was part of a regulatory system, and not a general growth factor. Neurobiologists believe that the brain wires itself as a result of experien...Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
...it appears that, for some veterans,the precautions prevented one set of problems and created another. Now,our task is to analyze the veterans' symptoms by investigating all the potentialcauses, not only for their sakes but for the welfare of future soldiers." The Duke study is one of a three-part investigatio...Project Shows Native Bacteria Can Destroy Widespread Pollutant In Groundwater
...xide near the wells kept down bacterial growth and prevented clogging. Also, the bacterial action showed no evidence of degrading over time. The researchers had promised to keep toluene levels below 20 parts per billion at the experiment's boundaries: Actual levels averaged one part per billion. "We've demonst...... efficiency in restoring drug sensitivity, andalso prevented a return to drug resistance. (Research was funded by the U.S.Public Health Service.) "We've been working on enzymes at Yale for 25 years or more, and it wasonlyr...Scientists Discover How Genes Work Together To Control Neural Development
... other hand, that overproductionof Phyllopod alone prevented accumulation of the Tramtrack protein as longas the Sina protein also was available in the same cell, which turned conecells into photoreceptor cells. "We consider that to be a dramaticchange," Lai remarks. "It tells us, as do our corresponding studi...Vitamin C Deficit Linked To Skin Disease
...adding vitamin C to culturesof chicken liver cells prevented the light-sensitive porphyrins fromaccumulating in...investigators found thatnormal levels of vitamin C prevented porphyrin accumulation in the liver. Thevitamin C is thought to act at the step that causes the bloc...Scientists Find New Trigger For Nerve Cell Death
...of potassium in thesolution bathing the cells also prevented apoptosis. This protective effect wasseen even in the presence of a substance that prevents calcium from flowing intocells. "These experiments don't rule out a role for calcium in apoptosis," Yusays. "But they do suggest that potassium outf...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
...her toxins may lead to lung cancer. Such damage prevented the gene from making a key protein, pRb-2/p130 , which suppresses tumor formation. They also saw evidence that levels of the protein correlated with tumor aggressiveness. This new work strengthens that finding. “We looked at 15...Pitt Researchers Construct Novel Delivery System For Gene Therapy Of Liver Disorders
...ccess cells that areactively dividing and thus are prevented from entering non-dividing cells. Others, like viruses, have structures that are easily recognized by the body asforeign substances and are either rejected or destroyed by the body's immunecells. Non-viral vectors, like the RCRs, can overcome these ...Curing Malaria, Controlling Mosquitoes Symposium Set For AAAS Meeting
...er speakers on the topic of whether malaria can be prevented whilealso protecting the diversity of mosquitoes will include Carole A. Long,Allegheny University of the Health Sciences, and Sheila Jasanoff, CornellUniversity. Following the presentations, discussants Marcia C. Linn, Universityof California-Berkel...Phase Out Planned For One Of Top Five U.S. Pesticides, Plant Doctors Respond
...lant varieties resistant to diseases methylbromide prevented Changes of cultural practices that increase the organic matterlevel of soil Soil solarization (the thermal heating of moist soil by sunlight) Electrical heating of soil Incorporation of biological control organisms What ever the alternative, "The l...Age-Based Screening Is Cost-Effective Method To Control Chlamydial Infection
...ll medical costs. They defined medicaloutcomes as prevented cases of pelvic inflammatory disease, chronic pelv...0. Screening according to CDC criteria would have prevented 64 cases ofpelvic inflammatory disease and saved $231,000. Screening all women younger than 30 yea...UF Researchers Use Gene Therapy To Prevent Hypertension, Organ Damage
...d that high blood pressure, orhypertension, can be prevented in laboratory animals, but UF researchersMohan Raizada, Craig H. Gelband, and Michael Katovich, of the departmentsof physiology and pharmacodynamics, believe this is the first animal studyto show the heart and kidneys also can be protected. One day, ...Pitt Researchers Develop Strategy To Use Dendritic Cells To Treat And Prevent Tumors
...of time to create a cancer vaccine thateffectively prevented tumor development in healthy mice and reduced tumors in 80percent of mice with established tumors, significantly prolonging theirsurvival. "Not only is this approach simple, but also it appears to be relativelyeffective, which suggests that t...Spinal Cord Injury Treatment May Improve With New Findings On Nervous System Damage
...ly after the cellswere three weeks old, and it was prevented by compounds that stop either AMPA orglutamate from overexciting the receptor. "So our discovery may have resulted from the fact that our oligodendrocytecultures were older than those that had been studied previously," Goldberg says. "Or it may have ...Molecular Memory Tunes Adrenaline To Stress
... of STREX-type channels dropped sharply. This was prevented by injecting ACTH artificially. The Science article is entitled, "Control of Alternative Splicing of Potassium Channels by Stress Hormones."...Inhibitor Shows Potential To Protect Infant Brain
...ize a cell's decision to self-destruct. If they're prevented from doing their job, cells can't commit suicide. "A major question in the field is whether it would be clinically useful to use caspase inhibitors to prevent apoptosis," Holtzman says. "So we tested the potential of a compound called BAF." BAF ......esterol readingis, lowering his or her cholesterol prevented further development of bloodvessel deposits that block blood flow to the heart and cause a heart attack. "We were able to demonstrate a profound effect on the atheroscleroticdisease process," says lead author, Stephen MacMahon, Ph.D., associa...Toxic Protein That Interferes With Brain Signals May Trigger Onset Of Alzheimer's Disease
...that clusterincould make amyloid protein toxic but prevented formation of fibrils. Based onthese results, the collaborative group subsequently found that a combination ofamyloid and clusterin results in the formation of ADDLs. Another of the researchers, Mary P. Lambert, developed tests todetermine ho...New Model Makes It Possible To Predict Emergence Of Antiviral Drug Resistance
...e, at least five drug-sensitiveinfections could be prevented on average for each case of drug-resistant geneticherpes. And since genital herpes is a risk factor for developing HIV, increasingtreatment rates of genital herpes could potentially also have an importantindirect and rapid effect on decreasing the in...