Drunken Fruit Flies Reveal Molecular Pathway Regulating Sensitivity To Alcohol
...studies in human cells. This discovery fit with a previous finding, namely thatamnesiac is believed to encode a molecule that stimulates cAMP production. The scientists thus deduced that the fruit flies missing the amnesiac gene hadreduced cAMP production, and that this action caused greater intoxication. T......elevatedprotein expression of TGF-" and EGFR. Our previous studies indicate that peoplewithout this disease produce low levels of TGF-" and very little, if any, EGFR,in the head and neck tissues," added Dr. Rubin Grandis. "Our findings have enormous potential. We could use this information toident...Successful Specialist Care For Cystic Fibrosis Patients From Childhood To Adulthood
...d Cambridge, the authors conclude that even though previous studies have supported a clinical benefit from specialist teams providing care in cystic fibrosis centres, their study provides good evidence to justify the system. Contact: Dr Diana Bilton, Consultant Physician, Cystic Fibrosis Unit, Papworth Hospit...Naked DNA Rejuvenates Rheumatoid Rodents
...e of TGF- plasmids to treat arthritis evolved from previous work by Dr.Wahl, director of NIDR's Oral Infection and Immunity Branch. These earlierstudies, which used the TGF- protein rather than the gene-containing plasmid,showed that TGF- could protect rats from arthritic joint destruction. However,it soon b...A New Molecular Marker For Prostate Cancer
... protein is found in virtually all normal cells.In previous studies, low levels of p27 protein in tumor cells have been shown topredict disease progression in breast and colon cancer. Researchers divided the 96 tumors into three groups, based on the percent oftumor cells in each sample expressing p27 protein...Penn Researchers Invent World's First Device To Rapidly Assess Lung Function
...specific assessment of progress oreffectiveness of previous therapies," says Bryan E. Marshall, MD,FRCP, co-inventor and Horatio C Wood Professor of Anesthesia atPenn. To date, extensive research has been conducted on thepulmonary function of normal rabbits with the MMIMS/MIGET methodusing small blood......, called VP4, was also an early victim-even though previous studiesshowed that it was usually buried inside the virus, 25 atom lengths from thesurface. "That's a lot of breathing," says Smith. "You think: how the devilcould that get out?" New Scientist issue 20th June 1998, page 19 Author: Philip Cohe......story of breastand ovarian cancer." In contrast to previous studies, the study did not find that women of AshkenaziJewish ancestry were more likely to carry a mutation in BRCA1 or BRCA2 comparedto women of other ethnic backgounds. This is probably because "this the firststudy to test for BRCA1 and BRCA2 in a ......rapy or having switched to a newregimen within the previous three months. About three-quarters of the patientshad been placed on a three-drug regimen that included a protease inhibitor. The researchers did not intervene in the patients' therapy or check ontheir compliance with the prescribed treatmen......nd does not correspond to virallevels in blood. A previous study by the Pitt group found differences betweent...said Dr. Gupta. "The good news is that a previous study by our group has demonstratedtreating HIV-infected men with a combination of three potent drug...Maryland's Death Rate For Pancreatic Cancer Surgery Reduced By Medical Regionalization
"We know from previous research that regionalization improves outcomes fortrauma and neonatal services, but this is the first study to show the samebenefit for elective general surgery." A move in Maryland toward regionalization -- centralizing particularmedical s...Harbor Branch Oceanographic Trains Displaced Fishermen And Women In New Careers As Aquafarmers
...1997. This represents an increase of 100%from the previous year in clam seed offered by the facility based in FortPierce. A new clam hatchery in the Aquaculture Development Park has recently been addedto the existing facilites and is now fully operational. The new facilitydemonstrates the next generation of...Researchers Take A Second Look At Homocysteine's Link To Heart Disease
...om points out the difference between his study and previous researchthat links elevated homocysteine with heart disease: Unlike otherinvestigations, his study was prospective -- it took a random sample of peoplewho had not been diagnosed with heart disease and followed them over time todetermine whether any o...Security Code Helps Immune Cells Attack Foe And Spare Self
...ccur in the restingcell and during activation, but previous methods failed to reveal this, so noone could make heads or tails of it," says lead researcher Paul M. Allen, Ph.D.,the Robert L. Kroc Professor of Pathology at Washington University School ofMedicine in St. Louis. "We tried a different approach, and...Common Anti-Viral Medication Prevents Severe Eye Herpes
... recur in patients who had the infectionduring the previous year. In both stromal keratitis and less severe fo...he countrywho had eye herpes infections during the previous year. About half thosepatients used acyclovir for one year. The other half took placebo capsules.Du...The Genetic Basis Of Childhood Schizophrenia
...CTG repeats wasfound in this population confirming previous findings which identified anassociation between ad...izophrenia and TREs. However, in contrastwith some previous studies, the association of large repeats with the COSsample seems confined to the male population. ...Severity Of Classic Heat Stroke Recognized
... issue of the Annals of InternalMedicine. "Unlike previous descriptions of classic heat stroke, most of the p... did not contribute to patientmanagement." Unlike previous studies of classic heat stroke, Ndukwu's team found that themajority (66 percent) of patients develo...Babbitt To Help Explore Depths Of Lake Tahoe
...ange from thousands of feet to bottomless,although previous work estimates the deepest part of the lake at about 1600feet. Reported contents include sunken ships and aircraft. Babbitt will board the USGS ship on Wednesday, Aug. 12, 1998 at 9:00 a.m. at the Tahoe City Marina at the Boatworks in Tahoe...Subtle Changes In Brain Receptor Gene May Have Significant Consequences For Addiction
...ependent persons in the study sample, confirming a previous result byone other researcher. The researchers also conducted binding studies using the A118G SNP or the mostcommon mu variant in cultured cell lines. They determined that A118G had athreefold greater binding with beta-endorphin than the usual mu op...Forecasting The El Niño-Driven Ebb And Flow Of A Rogue Mosquito
... hadvery large numbers of dengue cases compared to previous years, likely as aresult of our recent El Nino." H...e year, and how large the population iscompared to previous months and years," Hopp said. "Potentially, with the use oflong-lead climate forecasts, we may model...