Encouraging Results In Preclinical Studies Of Parkinson's Disease Gene Therapy
...ous L-dopa unnecessary. Thesedata further support previous findings that both of these two genes are requiredfor L-dopa synthesis in the brain and suggest a potential treatment strategy forpatients with Parkinson's disease. The mouse model used in this study was created in Dr. Palmiter's laboratoryusing gene...Experimental Drug Derived From Snake Venom Shows Promise In Reversing Effects Of Stroke
...ving an inert substance, orplacebo, regained their previous faculties. However, stroke patients whoreceived ANCROD were also at a higher risk of bleeding in the brain (5 percentof patients) when compared to those who received the placebo (2 percent). ANCROD is not yet approved by the Food and Drug Ad...Arctic indigenous leaders, scientists to study reindeer and caribou systems
...dongoing studies by the science community. Unlike previous meetings, this workshop will be an open forum in which debateand consensus is encouraged during the formulation of a strategy for futurescientific research. Representatives of the press are invited to attend andobserve the workshop according to the e...Duke Scientists Engineer 'Stealth Virus' To Deliver Genes
...denovirus to evade thefirst hit altogether. As in previous attempts to use the adenovirus as avector, they first deleted from the virus the "E1" gene -- which is the first ina series of genes the virus needs to copy itself. However, Amalfitano alsodeleted a second, similar gene farther down the same pathway...Deaths of Zoo Elephants Explained -- New Virus Identified
...suffered.After analyzing tissue samples from these previous deaths, the researchersconfirmed the elephants had died from herpesvirus, leading them to watch out forother cases. Other elephants were subsequently diagnosed with the virus, one inCalifornia in 1996, the second in Missouri in 1997, and the ...Brief Exposure To High Temperature Has Lasting Effect On Nervous System
...d into the desert can flynormally. We thought that previous heat exposure might have changed theproperties of the neurons somehow," says Ramirez. To test the idea that heat shock induces lasting modifications ofneuronal properties, Ramirez and Robertson exposed 50 locusts to 45 degreeCelsius temperatu...Chelation Therapy May Alter Immune System
... in humans as was observed in rats. "Our studyand previous studies prove that DMSA can do what it's supposed to. Itchemically binds with lead in the recipient and gets that poison out of thebody," says Rodney R. Dietert, the Cornell professor of immunotoxicology who ledthe study. "We knew that lead harms ......signaling system that inhibits cell division. (See previous news release,"PLANT-BASED FAT INHIBITS CANCER-CELL GROWTH BY ENHANCING CELL'S SIGNALINGSYSTEM, UB RESEARCHERS SHOW," at http://www.buffalo.edu/news/Latest/AwadPhyto .) The objective of the current study was to examine the influence ofvegetab...Substance Abuse May Curb Body's Stress Reactions
...thenoise. The findings are consistent with previous research suggesting thatalcohol and substance abuse develop, in part, from defects in individuals'"inhibitory control system," leaving them prone to impulsive behavior. Goodmodulators in the experiment were able to take advantage of the signal preced...In The Genes: Extra Belly Fat, Insulin Resistance Linked
...red toresult from genes. These findings agree with previous studies. But what about susceptibility to abdominal fat and diabetes? To determine thislikelihood, the investigators looked at how often a parent with insulinresistance had a child with extra belly fat and vice versa. If the same geneticfactors favor...Amphibian Revival: Build It And They Will Come
...oods. The researchers had historicalevidence from previous studies that both species were present in the area,although the last documentation of wood frogs dates back to 1911. Sexton counts the tally at the end of the spring breeding season. In 1974, thefirst year of the salamander census, 428 were counted,...Protein Adultery Revealed!: Mechanism Of Protein Folding Captured In Computer Simulation
...iscoveredproperties of folding that were absent in previous simulations." The problem was lessened by advanced algorithms and computer power available atSandia. To fold well or not to fold well: that is the question Says Istrail, "Jonathan [King], a laboratory biologist, proposed the problem. Hesaid that co...L.A.Times Book Prize Finalist: Book On Evolution Of Bird Flight
... since 1980. Theyrecognize books published in the previous calendar year that exemplifyexcellence in eight ca...lasStarr, published by Alfred A. Knopf. Among the previous winners in the categoryof science and technology are "How the Mind Works" by Steven Pinker, publishe...Antiviral From Advanced Viral Research Corp. Inhibits CCR5 Cell Receptor For HIV
...ed by Advanced ViralResearch Corp. which, based on previous history, has been show to be effectiveagainst a number of viral diseases. For further information, contact MarkAmster at 954-458-7636.......e allthe way to the actin cytoskeleton. In previous research, cytoskeleton researchers have worked from thebottom up, tracing their way backward from actin. They have found a bewilderingnumber of partial connections but have not yet made the leap to the membranereceptor. Working from the top down, neu...Dartmouth Medical School Researchers Discover Heavy Metal Contamination In Northern Mexico
...argely been ignored." Based on data from previous studies, Sargent estimates the average bloodlead levels in children living within 1 mile of the Torren smelter would beapproximately 40 mcg/dL. "Anything over 20 mcg/dL is harmful to children," hesaid. For infants and young children, lead exposure ......of both prostate and primary brain cancers.Several previous epidemiological studies also have shown an increased risk ofbrain and central-nervous-system tumors in families with clusters of prostatecancer. These observations led the Seattle researchers to evaluate the possiblelink between prostate and brain ca...Harbor Branch Scientists Discover Bioluminescent Octopus
...such as these that retain some indication of their previous function therefore offer valuableinsight into evolutionary history. Widder believes that the change from sucker to light organ may haveoccurred during colonization of the deep open-ocean by a creature that wasoriginally a shallow-water bottom-dwelle...New Genetic Findings In Attention Deficit Hyperactivity
...D5). The DAT1 results re-confirm and extend their previous findingsfor this polymorphism. Transmission of the 'associated' alleles at DAT1 and DBH is stronger in familial cases, but for DRD5, transmission isstronger in non-familial cases. Attributable fractions for DAT1, DBH and DRD5are calculated at .08, .1...Chemical Contaminants May Inhibit Cancer-Fighting White Blood Cells
...ntlyandeliminates them in 24 - 48 hours. However, previous studies in rats have shownbutyltins to have various toxic effects, including disruption of the immunesystem. Loganathan says his current study, using blood cells from adult male and femalevolunteers, was the first to demonstrate the effect of butylti...