UI Researchers Find Possible Genetic Link Between The X Chromosome And Ovarian Cancer
...rnal of the National Cancer Institute. The study's principal investigator, Richard E. Buller, M.D., Ph.D., UI professorof obstetrics and gynecology, and pharmacology, said the research suggests thata gene on the X chromosome that is involved with invasive ovarian cancer mayalso influence the effects of BRCA1, ...... archipelago. According to NCAR's Jeffrey Kiehl, a principal investigator for INDOEX,"In the future, pollution in the tropics will increase, so we'd betterunderstand it now. The chemistry in the tropics is severelyundersampled." The Indian subcontinent and surrounding nations are richsources for many kinds of ...UI Laboratory Develops Procedure To Study DNA Replication
...ociate professor of biochemistry and the project's principal investigator."Our procedure will allow us to examine these reactions in more detail." DNA is the genetic material that encodes all components in human cells. Eachcell contains more than two meters of DNA. Every time a cell divides, it isnecessary to ......an work for both skeletaland cardiac muscle," says principal author Hansell Stedman, MD, assistantprofessor of surgery at Penn's Institute for Human Gene Therapy, "so the nextstep will be to establish its safety and effectiveness in patients with thisform of muscular dystrophy." Stedman cautions that clinica......ent offisheries and oceans. Peterman, the principal investigator, says the team will use the moneyto develop methods for estimating productivity of salmon stocks and improvingpre-season forecasting of the abundance of Pacific salmon. "The abundance of Pacific salmon stocks fluctuates consider...Botanical Products Act Like Estrogen In Animals, Finds University Of Pittsburgh Team
...sor of medicine at the University of Pittsburghand principal investigator on the study. "These findings confirm reports thatthese plants relieve menopausal symptoms, especially hot flashes. However, westill need to conduct further pre-clinical tests with these substances to studytheir long-term effects and t......d for a ligand. "Phosphorylation might well be the principal method of modulation of this orphanreceptor," said Ingraham, "though we still cannot exclude the possibility thatSF-1 activity depends on a ubiquitous ligand present in most cell types." Other co-authors of the study were Irina Krylova, of the Depart...Researchers Discover A Common Protein's Deadly Role In Breast Cancer
...But the researchersfound that in breast tumors the principal form of the insulin receptor appearsinstead to be the growth-stimulating "fetal" form. "We have found that in these cancers, the insulin receptor largely reverts toits fetal stage, where its prime mission is to spur rapid cell division," saidIra D. G...Successful 'Green' Solvent Found For Problematic Chemicals
...cal engineering atthe University of Notre Dame and principal investigator of the study. Becausethe solvents evaporate easily into the air, factory workers may inhale them. Additionally, the solvents add to damage of the earth's atmosphere, becauseorganic solvents eventually will oxidize and create carbon diox...Researchers Discover Fast Efficient, Controllable Way To Study Molecular Interactions
...for studying protein interactions,"said Kodadek, a principal investigator for the Center for Biomedical Inventionsat UT Southwestern. "The technological spinoff will be when we can use thiscross-linking technique to determine a drug target within a cell." The other researcher on this study was Dr. Davi...Researchers Find Protein Abnormality Associated With Alzheimer's Disease
...explained and no cure is known. The study's principal authors are John Donahue, M.D., a neuropathology fellow; Tyler Berzin, a senior undergraduate; and Michael Rafii, anM.D.-Ph.D. student. The study was performed in Stopa's lab at Rhode Island Hospitaland the lab of Justin Fallon, ass...Report in Science on x-ray crystal structure of matrix Metalloproteinase-2 (MMP-2)
...tissue. MMP-2 acts directly on type IV collagen, a principal component of the basallamina, a specialized form o...increasing the degradation oftype IV collagen, the principal substrate of MMP-2 and the main structuralcomponent of the basal lamina, thus providing the means fo...Stakeholders improve global change assessment
...scientist and professor,agricultural economics and principal investigator; Robert O'Connor, associateprofessor of political science; Richard Bord, associate professor of sociology;James Shortle, professor of agricultural economics and rural sociology; DavidDeWalle, professor of forest hydrology; and Brent Yarn......y of California-LosAngeles (UCLA), Dr. Melmed is a principal investigator funded by the NationalInstitutes of Health. He has served as editor in chief for a number of scholarlypublications, including Pituitary, Endocrine Updates and Endocrinology, and iswidely published in scientific journals. He is also the p...U-M and Israel launch major international cancer study
...rt ofthe story," says Stephen Gruber, M.D., Ph.D., principal investigator of thestudy, and assistant professor of internal medicine and epidemiology in the U-MHealth System. "Many people with a genetic susceptibility to colon cancer neverdevelop the disease, and we need to figure out why. If we can recognize...... enormous," said Dr. Robert E. Schwerzel, a principal research scientist at the Georgia Tech Research Institute (GTRI). "These coatings could, in principle, replace many of the solvent-based paints, enamels and varnishes that are currently used to coat everything from stoves ...Scientists grow blood-producing stem cells outside the body
...hool ofPublic Health and Community Medicine, and a principal investigator at theSeattle Biomedical Research Ins...tside of an animal," he said. Bartelmez is principal author of the study, which will be published July6 in the Proceedings of the National Academy of Sci......se before a T cell can respond. Dustin was principal investigator of the study. The lead author, ArashGrakoui, Ph.D., performed many of the experiments while he was a graduatestudent in the laboratory of co-author Paul M. Allen, Ph.D., the Robert L. KrocProfessor of Pathology. Other researcher...CU-Boulder to send experiments ranging from ladybugs to water quality on NASA shuttle
...," said BioServe Associate Director LouisStodieck, principal investigator on the STARS program. Since space stationastronauts will grow plants for food, the Chilean students proposed a testinvolving the behavior of ladybugs and their primary prey, aphids, in lowgravity. The objective will be to document the mo...Drug users, Native Americans susceptible to infectious diseases
... the consequences of its infection." Murphyis the principal investigator of the study. Study participants were recruited between November, 1990 and February, 1993 fromfive major blood donation centers across the United States and six smaller bloodbanks in San Francisco and Los Angeles. The study cohort was m...