Bacterial Toxin Surprises Scientists
...'s lead scientist, Dr. Alan Finkelstein, a professor in the Department of Physiology and Biophysics and the Department of Neuroscience. "Why do we care about that? Because it is relevant to all the proteins that end up inserted in the cell's membrane [such as hormone rec......icit drugs. Marc Caron, a Hughes investigator and professor of cell biology at Duke,said initial studies with the mice already have yielded surprising insightsthat challenge conventional theories about drug addiction and Parkinson'sdisease and may provide the first realistic model for testing new treatmentsfo...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...normal cells. Reporting the findings are assistant professor of pharmacology Ann Marie Pendergast, and graduate students David Cortez and Lisa Kadlec. In a third paper in the Nov. 21 Proceedings of the National Academy of Sciences, Mikhail Gishizky of SUGEN Inc. along with Pendergast and Cortez reported succes...Researchers Pinpoint Site For Petit Mal Seizures In Brain
...er side effects, said Dr. David Hosford, assistant professor of neurology at Duke and the Durham Veterans Affairs Medical Center. Petit mal or "absence" seizures affect 100,000 children in the United States and account for one-fifth of all childhood epilepsies. About 20 percent of children with petit mal seiz...Tumor Suppressor Gene Located In Liver Cancer Cells
... association with viral hepatitis," said Jirtle, a professor of radiation oncology and cancer center member. The lack of effective treatments also makes it a particularly deadly disease, he said. "As a consequence, knowing something about liver tumor formation or having a handle on how one could detect these ...New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
...journal Science, are Christian Raetz, chairman and professor in the DukeUniversity Medical Center department of biochemistry, and Steven Roderick,assistant professor at the Albert Einstein College of Medicine departmentof biochemistry. Their research is sponsored by...Second Breast Cancer Gene Located
... chairman of the National Cancer AdvisoryBoard and professor of community and family medicine at Duke. "Butit m...reastcancers," said Futreal, an assistant research professor of surgeryand assistant professor of genetics. "Our findings strongly suggestthat BRCA2 accounts for...Duke Geologists Explore Alternative Way To Measure Ice Age Sea Bottom Temperatures
...culation drives climate change," said Duke geology professor Paul Baker, another author of the Science paper and a supervising geochemist. "The temperature of the deep water through time is very poorly understood because there hasn't been any unambiguous paleothermometer developed." The researchers cautioned t......omically distinct from Homo sapiens. Working with professor Guanjun Shen of the University of Guizhou in China...n the 200,000- to 300,000-year-old range. Ku - a professor in the Department of Earth Sciences who was recently elected to fellowship in the American Geophysic...Computer Program For Quicker, More Detailed Mapping
...r availablewhole genome maps," said Dr. David Cox, professor of genetics and co-directorof the Stanford Human G...about how tomake a human body, said Richard Myers, professor of genetics and directorof the Stanford Human Genome Center. "Previously, it would take months for ...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...he lead authors of the paper. Blackshear also is a professor ofbiochemistry and medicine at Duke medical center. To date, doctors have not identified any specific genes for autoimmunediseases such as rheumatoid arthritis, although many researchers believethere may be several genes that, when defective, predi...Heat-loving Microbe Repairs Its DNA With Light
...pair the damage. However, Dennis Grogan, assistant professor ofbiological sciences at the University of Cincinnati, found thatthe repair process requires assistance from the environment, inthe form of visible light. This light-driven repair of DNA, knownto microbial geneticists as "photoreactivation," is the f...Children Become Gorillas In VR Zoo
...asrealistic as possible, said Hodges, an associate professor in GeorgiaTech's College of Computing andan asso...researchers --led by Hodges and Wineman, associate professor and director of thedoctoral program in the College ofArchitecture -- used photographs, videos, conto...From Corn Rootworms To Art, Cornell's Reactor Is At The Core
...source to study, along with Paula Davis, assistant professor of entomology, the behavior of this major corn pes...ornell faculty in a variety of areas. W. S. Taft, professor of art, has used neutron induced autoradiography to peer beneath layers of pigments on a painting to...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...nformation,according to Bruce Sullenger, assistant professor of experimental surgeryand genetics. The Duke team already has begun exploring use of these newtherapeutic approaches for sickle cell anemia and even to "sabotage"the AIDS virus. "This research proves that we can use nature's ownprocesses to rewrite...Freshwater Sponges May Pose Threat To Zebra Mussels
... in the late 1980s, said David Kelch, an associate professor with OhioState's Extension Sea Grant program. W...e paper, along with Fred Snyder, also an associate professor with Ohio> Sea Grant, and Anthony Ricciardi and Henry Reiswig, with McGill University in Montrea...Transgenic Rice Plants Resist Insects, Drought And Salt Damage
... to insect pests or drought," said Ray Wu, Cornell professor of biochemistry, molecular and cell biology, and leader of the international team that spliced other plant species' genes into rice. "Hundreds of millions of hungry people need this rice now, and the crop losses to insects, drought and increasing sa...Race Plus Roaches: A Breathtaking Link
...ependent of poverty," says Peyton Eggleston, M.D., professor of pediatrics and co-author of the study. Eggleston speculates that racially based genetic differences, important in the regulation of immune responses, hold a clue. Low socioeconomic status forces families to live in substandard housing, whether urb...Mutate Or Die: New Polymerase Gives Desperate Yeast An Option
...not replicate and die," says Christopher Lawrence, professor of biophysics. Working with Lawrence on theproject...partment ofBiophysics, and David Hinkle, associate professor of biology. There have been hints of a previously unknownpolymerase in yeast, but only with re......st-doctoral researcher in CIRCE; Daniel K. Youngs, professor of entomology at the University of Wisconsin, Madison; Maria Eisner, research support specialist at CIRCE; Braden Roach, a Cornell postdoctoral researcher at the time of the studies and now a staff scientist at the Ithaca-based pharmaceutical-devel...