Tag: "profiling" at biology news

Rosetta Inpharmatics approach enables identification of gene functions

..."The compendium approach to global gene expression profiling described and demonstrated by Rosetta Inpharmatics...npharmatics provides a proprietary gene expression profiling platform, consisting of hardware and software products, that uses gene expression profiles to provid...

University of Georgia geneticist among the first to study genetic mating systems of fishes and turtles

...ssist with the job." Among these tools are new DNA profiling methods based on molecular markers called microsatellites that can, along with a technique called the polymerase chain reaction, identify parents and their offspring using only tiny bits of tissue. The researchers have continued to document numerous ...

Millennium's LDP(PS)-341 inhibits growth and induces death of cancer cells, appears to overcome chemotherapy resistance

...atform, including state-of-the-art transcriptional profiling and proteomics expertise. Millennium, a leading biopharmaceutical company, applies its comprehensive and integrated science and technology platform for the discovery and development of breakthrough therapeutic and predictive medicine products, wit...

Researchers identify 170 genes involved in Crohn's disease and ulcerative colitis

...ts over the course of the diseases and use genetic profiling to track disease progression, identify early and late changes, and ultimately help to develop better predictors of severity as well as target therapies for each IBD type." Crohn's disease and ulcerative colitis primarily affect the intestines, result...

Cancer-detecting microchip - a micromachined cantilever - is sensitive assay for prostate cancer and potentially other diseases, researchers report

.... "This could lead to fast screening and molecular profiling for many diseases and a possible cancer chip for detecting cancer." "A big advantage of this technology is that one could look at multiple markers in a single reaction, whereas currently available assays require a separate reaction for each analyte,"...

New study could cut overtreatment

...ast cancer samples to be able to apply micro array profiling to young breast cancer patients in general. "Cancer patients younger than 55 whose cancer has not spread to the lymph nodes are not only treated by surgery and radiotherapy but also generally receive adjuvant treatment (chemotherapy and/or hormone th...

Other highlights in the April 3 issue of JNCI

...er, detecting such changes through gene expression profiling alone is an extremely complex task. Deepak Agrawal, Timothy J. Yeatman, M.D., of the H. Lee Moffitt Cancer Center, Tampa, and colleagues investigated the feasibility of sample pooling in combination with a novel analysis algorithm to identify marker...

U-M scientists find new genetic marker for prostate cancer

...he U-M Medical School. Since genetic and molecular profiling compares genes and proteins from normal cells to those from malignant cells in various stages, the U-M is developing other comprehensive tissue banks, so the technology can be applied to more types of cancer including lung, ovarian, breast and color...

Ten new candidate genes associated with salt sensitivity and hypertension are identified in rats

...thodology A powerful new approach, transcriptional profiling using DNA microarrays, was used to probe the genetics of hypertension in general and salt-sensitivity in particular. This is the same methodology that is being used to study other complex diseases such as cancer and schizophrenia. This approach perm...

Genetic factor underlies weight gain after use of antipsychotic drugs

...common in the surgery of the future, where genetic profiling would be used to indicate the most effective and least harmful treatment, individualised for the patient." (quote by e-mail; does not appear in published paper)....

Researchers identify genes associated with aging of the retina

...icroarray technology is an important tool for gene profiling because it allows rapid comparison of thousands of genes, something that was unheard of even few years ago. Shigeo Yoshida, M.D., Ph.D., a post-doctoral research fellow in Swaroop's laboratory, examined microarray slides containing DNA from 2,400 hum...

Gene profiles predict survival

...ct cured by standard chemotherapy. Gene expression profiling successfully identified each of these. To identi...o treat breast cancer and leukemia. Hurt said gene profiling will make it possible to obtain more information from clinical trials in the future....

Breakthrough in profiling of yeast genome

...he results of the first-ever comprehensive genetic profiling of any organism, in this case yeast, which has pro...l Nature includes an article entitled, "Functional profiling of the Saccharomyces cerevisiae genome." Canadian authors include a team led by McGill University Bi...

ASPB Annual Meeting, August 3-7, media tip sheet

...radigm Genetics, Inc. -- speaks on gene expression profiling in an era of high-throughput biology.John Yates, Torrey Mesa Research Institute -- addresses proteomics in the postgenomic era.Richard Threthewey, Metanomics GmbH & Co. KGaA -- speaks on functional genomics with small molecules: the industrialization...

Would 'race' disappear if the United States officially stopped measuring it?

...pt and apply it in different circumstances. Racial profiling in law enforcement activities, "redlining" of predominantly minority neighborhoods in the home mortgage and insurance industries, differential medical treatment, and tracking in schools, all exemplify social practices that sociologists study and want...

Cloning pigs and drug discovery among 'hot' topics

...olerance Network, said small-scale gene expression profiling has led to the identification of genes that appear...plication of global gene and/or protein expression profiling in transplantation offers the opportunity to identify new surrogate markers for monitoring the effec...

Researchers identify first genomic blueprint of cancer preventive compound found in broccoli

...the journal Cancer Research, and is the first gene profiling analysis of a cancer-preventing agent using this approach. The researchers believe the findings provide a better understanding of the body's defense mechanisms and could lead to the identification of other cancer-preventing food compounds and strateg...

UT Southwestern researchers find protein that both instigates, inhibits heart growth in mice

...lls in mutant compared to wild-type mice, and gene profiling showed that 179 genes had elevated expression and 90 genes had reduced expression. The researchers believe that HOP works by controlling levels of serum response factor (SRF), a gene-activating protein, during heart development. SRF and three sibling...

Database lets researchers worldwide access genome of malarial parasite

...an and from the liver to the blood. Transcription profiling allows scientists to examine how and when all the genes in the genome are turned on, such as during exposure to drugs used for chemotherapy. While Plasmodium falciparum causes the most devastating form of human malaria, several other species also c...

Smart materials expand within global marketplace

...Ps, electrochromic materials and fullerenes, while profiling R&D efforts at more than two-dozen organizations and reviewing companies that have smart material-based products on the market or in development. Smart Materials also cites research activities at universities and government organizations worldwide. T...

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