Tag: "progestin" at biology news
Ligand Scientists Discover Tissue-Selective Female Hormone Mimics
...red in thejournal describe two novel non-steroidal progestin
compounds, (S)-LG120746 and(S)-LG120747 that were ...nical advantagesover currently available steroidal progestin
therapies," said Dr. AndrésNegro-Vilar, Ligand Senior Vice President and Chief Scientific Offic...
Test For Genetic Trait May Indicate Heart Benefits Of Hormone Replacement
...age 58 years. Half of thewomen took estrogen plus progestin
and the other half took a placebo. Afterfour months, the researchers reversed the two groups' medications."We wanted to test if the reduction would be greatest in the pattern B women,which we believed it would be based on clinical experience," Super...
Penn Researchers Awarded $10 Million Grant To Study Link Between Genes And
... and todetermine whether the anti-estrogen steroid progestin
can helpoffset the increased risk of uterine cancers when added totraditional hormone replacement therapy, which consists ofestrogen alone," explains Brian L. Strom, MD, MPH, principalinvestigator of the study and Chair of the Department ofBiostatist...
FDA clears Berlex Laboratories Mirena (R), new form of long-acting contraception meets need for U.S. women
...t contain estrogen. It delivers a low dose of the progestin
levonorgestrel directly to the lining of the uteru...rch at the University of Pittsburgh. "Because the progestin
in MIRENA is released just within the uterus, it provides very effective contraception with very few...
A pill for reversible suppression of periods - a new option
...sants are novel in that they use very low doses of progestin
antagonists administered for as long as a woman desires to suppress menstruation, and that once the treatment is stopped normal cycles begin again in a very short time. The fact that we have an animal model with a cycle identical to that of a woman h...
New study shows oral contraceptive may be effective in treating severe form of premenstrual syndrome
...er-Based Medicine show that the combination of the progestin
drospirenone with the estrogen ethinyl estradiol contained in the oral contraceptive Yasmin may be beneficial in treating premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome (PMS) that affects more than 3 million U.S. women...
Selected estrogen compounds modify risks of vein clotting, a response to hormone replacement theraphy
... reasons. After menopause or partial hysterectomy, progestin
is administered at the same time to offset an increased risk of endometrial cancer. In some amenorrheas, estrogen is given to restore menstrual cycle, and if therapy is unsuccessful, this may indicate the presence of pathology, for instance, pituitar...
Estrogen doesnt prevent second strokes: protective effects of hormone replacement therapy challenged
...ing these women with a combination of estrogen and progestin
did not reduce heart attacks or death from heart disease. That study also found no reduction in strokes among women who received the study drug. Additional information about the benefits and risks of hormone replacement therapy is expected from th...
Alternative to hormone replacement therapy shows promising results
...e, estrogen (Premarin), and estrogen combined with progestin
(PremPro). A fifth group of monkeys received no drug treatment. The monkeys received drug doses designed to approximate the levels women are normally prescribed. They were fed a moderately high-fat diet (42 percent of calories from fat) designed to s...
National study halted since health risks exceed benefits in postmenopausal women on estrogen
...domized, placebo-controlled trial of estrogen plus progestin
in more than 16,000 women with a uterus," said Dr....l Hill School of Public Health. "The estrogen plus progestin
trial was stopped early -- after 5.2 years -- because of a 26 percent increased risk for breast canc...
Oral contraceptives increase C-reactive protein, an infIammatory biomarker
...he 1960s. Among women using the then "low dosage" progestin
oral contraceptives, the study found no difference in the prevalence of positive serum CRP between this class of OC users versus nonusers. Given the current availability of the high sensitivity CRP test, it is possible to assess the effects of curre...
New national studies show combined hormone replacement therapy boosts stroke, dementia
... taking a combination of the hormones estrogen and progestin
did not improve the quality of life for women who ...f such symptoms, saying the risks of estrogen plus progestin
outweighed the benefits. The latest findings from Women's Health Initiative studies provide new evid...
Genetic differences revealed by SNPS play a role in risk, prevention and outcome for cancer
...for breast cancer -- when undergoing estrogen and progestin
therapy (EPT). Mammograms used in the study were obtained from 233 postmenopausal women aged 45-75 years who had participated in randomized trials with EPT, estrogen alone or a placebo. individuals who might respond better to compounds naturally...
Genetic clues may show which women face breast cancer risk from HRT
...oped denser breast tissue after using estrogen and progestin
therapy than women without the variant. Mammograp... use hormone replacement therapy with estrogen and progestin
go on to develop breast cancer," says Giske Ursin, M.D., Ph.D., associate professor of preventive me...
New advances in thrombosis help further understanding of disease prevention
... that the associated health risks of estrogen plus progestin
(E+P) outweighed the potential benefits of the tre.... "While our results showed that estrogen plus progestin
did not increase the risk of thrombosis to a larger degree among older or obese women, age and body ...
Applying results of women's health initiative study to individual patients
...udied the effects of a combination of estrogen and progestin
on the prevention of chronic diseases, was ended in July 2002, after researchers found that combined HRT was putting women at risk for heart attacks, breast cancer, strokes and blood clots. "There are many women for whom HRT continues to be an excell...