Tag: "progression" at biology news
Beyond the French paradox
...of atherosclerotic lesions as well as inhibit the progression
of existing lesions. In some cases, alcohol appears to have protective properties against heart disease. "Even though the French eat a lot more cholesterol than we do," said Eugene E. Emeson, professor of pathology at the University of Illinoi...
Cellular membrane changes associated with acclimation to cold
...used on cellular changes seen during the step-wise progression
into hibernation, brought on by seasonal changes. This is one of the first studies to observe the cellular effects that accompany the rapid changes in body temperature occurring during deep hibernation. "This study shows a physical membrane change t...
New data suggest anakinra may accelerate reduction in joint destruction and improve quality of life for rheumatoid arthritis patients
...stration, may accelerate reduction in joint damage progression
and improvement in the health-related quality of life for RA patients, according to results of several studies presented this week at the American College of Rheumatology (ACR) annual meeting. Bone and Joint Data In a double-blind, multicenter st...
AIDS vaccine study harnesses 'killer' immune cells to control virus, prevent disease in animals
...is study suggest that a vaccine might slow disease progression
after an infection has occurred and decrease the likelihood of an infected individual transmitting the virus. This could have important ramifications for the AIDS epidemic," says Letvin, also a professor of medicine at Harvard Medical School. "Th...
UCSF-led study offers insight into cancer development, resistance to therapy: finding focuses on Ras oncogene
...tions in the Ras oncogene occur quite early in the progression
towards colon cancer, while p53 is degraded quite late. "Given the circumstances we've described, there could be large number of tumors in which mutant Ras plays a role in keeping p53 turned down," he says. Phase I (toxicity) trials of drugs that inh...
Gene therapy shown to protect and reverse the debilitating effects of Parkinson's disease in pre-clinical studies
...study suggests a new approach to forestall disease progression
in newly diagnosed Parkinson's disease patients by delivering potent trophic factors with effects that are long-term and non-toxic," Kordower noted. He anticipates that clinical testing in humans of the lentiviral delivery system for GDNF will beg...
Amgen introduces new rheumatoid arthritis book and first online resource for access to interleukin-1 (IL-1) research
... that IL-1 plays a fundamental role in the disease progression
of rheumatoid arthritis," said Keith Leonard, vice...inical information on the role of cytokines in the progression
of rheumatoid arthritis and the potential for novel, anticytokine-based therapies. Other Web site h...
UCSF-Harvard team publishes major HIV therapy study over objections of sponsor; compound shows no effect on slowing disease progression
...s have provided, the risk for eventual HIV disease progression
remains high. Mild viral immunizations, with prod...ed the major characteristics associated with HIV's progression
to AIDS, including low counts of CD4+ T-cells, and potentially lethal opportunistic infections, such...
Evidence links protein damage to Parkinson's
...ss may be a primary event leading to the onset and progression
of neurodegenerative synucleinopathies, particular...the oxidative damage, and thus slow or reverse the progression
of these diseases." In the United States, Parkinson's disease affects over a million people, and Al...
SFVAMC/UCSF researchers develop lead for a new Alzheimer's disease drug - a fragment of a brain growth protein
...ating drugs that prevent the onset and/or slow the progression
of Alzheimer's disease," he said. Most of the results presented by Longo were also published in the September 22 issue of the Journal of Biological Chemistry. Co-authors on the study were Youmei Xie, MD, UCSF/SFVAMC postdoctoral researcher in neuro...
Research sheds light on heart valve disease caused by fen-phen
...ve disease. "Since serotonin may also affect the progression
of valve disease, the effects of tryptophan in ones diet may turn out to be important," said Dr. Levy. One next step, he added, is to design clinical studies to further explore possible links between serotonin levels, tryptophan levels and valve ...
Manganese exposure may speed the emergence of Parkinson's disease symptoms, according to new findings in animals
...mimicking the early neurodegenerative state in the progression
of Parkinson's disease. Treated and untreated rats were then given low doses of manganese. The manganese had no effect on dopamine levels in the substantia nigra, but caused significant impairment of neurologic functions. Furthermore, some of the neu...
'Translocation' surgery yields unprecedented results
...e. PDT can't restore vision, but it can halt the progression
of the disease. De Juan says the fix is temporary, and some patients who receive PDT need surgery later. De Juan stresses the importance of early management of AMD: "Macular translocation is effective only for people just diagnosed. Once they'v...
Team identifies first drug therapy for rare, precancerous stomach illness
...ten required for symptom relief and to prevent the progression
to cancer. The 48-year-old Texas man was referred to Coffey from the University of Texas-Southwestern Medical Center in Dallas with endless vomiting - before treatment, he was vomiting an average of 70 times a week. "He was miserable," Coffey said. ...
Scientists suspect new genetic risk factor for late onset Alzheimer's disease
...lopment of AD, treatments can be developed and the progression
of the disease can be slowed or stopped. It is estimated that up to 4 million Americans currently suffer from AD. The researchers studied a number of populations of people with AD. In part of their research, both the Tanzi and the Goate groups stud...
Novel protein is both ion channel and enzyme
...TRP is melastatin, whose action seems to block the progression
of the skin cancer melanoma." A possible involvement in cell proliferation, along with the fact that the PLIK kinase interacts with phospholipase C, leads Clapham and his colleagues to believe that they might have found a promising metabolic control...
UNC-CH study indicates special vaccines could prevent insulin-dependent diabetes
... importantly, the scientists say, they also halted progression
of the illness in animals already affected. " This work is very encouraging because it has the potential to be useful in clinical settings," said Dr. Roland Tisch, assistant professor of microbiology and immunology at the UNC-CH School of Medicin...
How sensitive is your brain to alcohol-induced damage?
...hol-induced brain injury may be the medium for the progression
of alcoholism. The summary, published in the Febr... from alcohol consumption is sum and parcel of the progression
of the illness," said Peter R. Martin, professor of psychiatry and pharmacology, and director of the...
Humans at work and play in high altitude environments
...ltitude studies into the genetic cause and medical progression
of hypoxia may provide answers for people at sea-level who experience hypoxia as a major consequence of lung and heart disease or sleep disorders, as well as for individuals who play or work at high altitudes. On Feb. 18, during the annual meeting o...
Tips from the Journals of the American Society for Microbiology: March 2001
... This model of AIDS is supported by evidence that progression
to AIDS in humans is measured by a decline in CD4 ... virus in the blood, stops and most often reverses progression
of the disease. Scientists have known for years that African green monkeys can be infected wi...
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