Clemson researcher receives Komen grant
...reast cancer." Scientists have learned that human prolactin (PRL), a hormone normally produced in the brain and mainly responsible for mammary gland development and milk production, may be involved in breast cancer development. "The involvement of PRL in breast cancer is likely due to, in some cases, the fact...With flu season coming, don't forgetexercise?
...mmunostimulatory factors (such as growth hormones, prolactin and cytokines), which in turn activate various immune cell populations. Exercise bouts of moderate duration (<60 min) and lower intensity (<60 %VO2 max) have been associated with enhanced activity of immune parameters, including macrophage c...Age-related decrease in physical ability may be in the genes
... times higher in the young mouse cerebellum, while prolactin gene expression was nearly 15 times higher in youn... see if caloric restriction prevents a drop-off in prolactin and growth hormone," Rotter said. "If it does, that would imply that the genetic pathways for making...Adult alcoholism and attention-deficit hyperactivity disorder are connected
...tructures responsible for the fenfluramine-induced prolactin release are the 5-HTT and the 5-HT2c receptors. Therefore, both seemed plausible as overlapping sources of genetic liability of ADHD and alcoholism." Neither of them, however, appear to be genetic risk factors in the sample examined. "Our data demo...Hormonal changes in satisfied and dissatisfied shift workers across a shift cycle
...egulation of several hormones including cortisol, prolactin and growth hormone in both shift/night workers as well as other populations. Workplace studies have shown that working nights and being on-call are not only related to increased adrenalin release, but also to reduced levels of testosterone. A Ne...Researchers discover effective method for killing prostate cancer cells
... by Dr. Nevalainen and colleagues established that prolactin serves as a local growth factor for prostate cells...nd that Stat5 is the specific signaling device for prolactin in prostate cells. In other words, Stat5 acts as an internal signaling device within the cell, rece...Discovery of how prolactin travels to gene's machinery helps explain its role in breast cancer
...of prolactin's role in cancer, has discovered that prolactin functions directly inside the cell, not merely by ...de hormones. Dr. Clevenger also has discovered how prolactin is able to travel across the cell membrane and directly into the DNA machinery of the cell. These f...JCI table of contents, January 15 2003
... addition to playing a critical role in lactation, prolactin is thought toaffect cells of the immune system and augment autoimmunity. Both B and Tcells express prolactin receptors, and the hormone has been shown toinfluence T cell development and proliferation. Focusing...JCI table of contents: October 1, 2002
...***************************************** Lack of prolactin receptor signaling in mice results in lactotroph p...negative feedback loop that involves the action of prolactin on dopaminergic neurons in the hypothalamus. Subsequent neuronal dopamine release and binding to lac......follicle-stimulating hormone, luteinising hormone, prolactin and several different prostaglandins. Some of these have been detected in a women's blood within hours of exposure to semen. The question many people will ask is whether oral sex could have the same mood-enhancing effects. "Since the steroids in birt...New depression studies reveal persistent serotonin system abnormality in patients
...ects -- the UNC team measured changes in levels of prolactin and several other hormones released by the pituitary gland at the base of the brain in response to the serotonin challenge test. Their goal was to learn whether the abnormality was always present or detectable only when patients were depressed and di...Dairy scientist advances field of transgenics and knowledge of growth hormones
... He reports that Akers was the first to prove that prolactin is essential for normal onset of lactation in rumi...w that iodinated human GH could be used to measure prolactin receptors in cattle. His expertise in applying cell culture techniques is unsurpassed, Sejrsen says,...Breast cancer cells shown to migrate toward hormone source - novel mechanism for metastasis seen
Acting as a chemical attractant, the hormone prolactin stimulates thecoordinated movement of breast cance...to show that breastcancer cells will move toward a prolactin source in cell culture and even crossa membranous barrier to reach the source. Also revealed...