A paradox helps explain how aspirin works
...including causing contraction of smooth muscle and promoting inflammation. Specifically, aspirin inhibits an enzyme, cyclo-oxygenase (COX), that catalyzes the generation of prostaglandin from cell membrane fatty acid precursors. But the suppression of prostaglandin production could not fully account for aspiri...UCSF studies illuminate possible new landscape for targeting cancer
...veness, and such characteristics as what factor is promoting angiogenesis. And this is occurring in tumors cont... that another protease, MMP-2, is also involved in promoting tumor growth. The absence of MMP-2 did not affect angiogenic switching, but it did reduce tumor size...Sequencing the human genome: unraveling the mysteries of health and disease
...c discrimination in different settings as a way of promoting the sharing of information and public dialogue on this important set of issues. Announcing the first in a series of breakfast seminars on concerns related to genetic discrimination. WHO: Dr. Francis S. Collins, Director, National Huma...DFG set up 19 new Graduiertenkollegs
...h co-operation partners world-wide in the field of promoting junior scientists. And in future, it will be possible for Graduiertenkollegs to submit additional applications supplementing the international funding programme "Promotion an Hochschulen in Deutschland" (PHD), which is run jointly by the DFG and the ...Laser treatment reduces scarring after heart attack
...rocesses improves the cellular response to wounds, promoting healing and muscle regeneration after injury. Mitochondria are rod-like structures in the cytoplasm, the substance of the body of the cell in which most cell activities occur. Mitochondria serve as the center of cellular enzyme activity. In the st...Progenitor cells can have protective effect against brain trauma
...e nave cells.According to McIntosh, in addition to promoting nerve growth, NGF also induces brain cells to produce more antioxidant enzymes, which remove the free radicals that may trigger apoptosis. "The NGF-producing cells provide cells with an added resistance against the dangerous environment of an injured...Science board honors the Bronx Zoo's Education Division for public service
...ffective conservation organization, protecting and promoting a world rich in wildlife and wilderness," said Annette Berkovits, Senior Vice President of the WCS Education Division. "WCS manages more than 300 field projects in 53 countries in addition to the award-winning environmental education programs for sc...New U. of Colorado research may reduce renewable fuel costs
...enewable fuels from plant biomass, said Danna. "By promoting the development of renewable fuels, our work should have significant economic and environmental impact," she said. "An established biofuels industry will strengthen U.S. agriculture and reduce our countrys dependence on foreign oil." Ethanol, also k...Understanding tuberous sclerosis
...such a way as to decrease the effect of insulin on promoting cell growth. Drs. Gao and Pan found that fly cells deficient in TSC1 display increased cell size, as is also sometimes true in tumors derived from human TSC patients. Further delineation of the role of TSC1 and TSC2 in cell growth regulation will pr...UCSD biologists identify 548 genes in the fruit fly likely to play a role in human genetic diseases
...at the Homophila database is an important link for promoting collaboration between human and fruit-fly geneticists. "You can't easily use mice to perform a genetic screen for new genes that may play a role in disease. The fly offers a compelling advantage that doesn't exist in the mouse."...Both smells and pheromones may arouse instinctive behaviors in mammals
...nes can have a significant effect on pest control, promoting endangered species, and, perhaps above all, for understanding our own sense of smell and associated behaviors." Signals from a mammal's nose caused by normal smells called odorants go to various places in the cortex, in the upper part of the brain, w...BioMed Central to deposit e-journals with the British Library
...All these initiatives, combined with the policy of promoting self-archiving by authors, means that all research articles published on BioMed Central will be permanently accessible and searchable in multiple archives.......reatment activates glucose uptake to the muscle by promoting the cell surface delivery of cytoplasmic storage vesicles that contain the glucose transporter GLUT4. Like other examples of regulated membrane dynamics, this process involves the local rearrangement of the cortical actin cytoskeleton. Tong et al. h...Integrins and signaling in psoriasis
...high MAP kinase activity in suprabasal cells, thus promoting keratinocyte growth. Analysis of these cells maintained in organ culture suggests that this transgene delays terminal differentiation by transit cells and generates a thickened basal layer much like that seen in psoriasis. Because an inhibitory form......errant reactions with proteins and enzymes, and by promoting the formation of destructive active oxygen species. Phytochelatins have been known in plants as a means of detoxifying heavy metals for some 15 years. Phytochelatin synthase works by polymerizing glutathione, a sulfur-rich peptide with a high affini...USF Alzheimer's vaccine research boosted by $1.1-million NIH grant
...l role that cellular immunity plays in fighting or promoting the devastating neurodegenerative disease. "We want a more well-rounded, extensive understanding of the immunological responses to the Alzheimer's vaccine, particularly potential cellular immunity, to determine whether the responses are beneficial or...Europe and United States assess international support of science in Russia and Ukraine
...tml . The Royal Society is an independent academy promoting the natural and applied sciences. Founded in 1660, the Society has three roles, as the UK academy of science, as a learned Society, and as a funding agency. It responds to individual demand with selection by merit, not by field. The Societys objectiv...Scientists at UCLAs Jonsson Cancer Center discover gene's role in regulating stem cells in the brain
...TEN, the brain stem cells receive too many signals promoting their development through two kinases, or proteins, called PI3 and Akt, which are part of the cell-signaling pathways. The stem cells become over-stimulated and rapidly mature into brain cells whose growth and functions cannot be controlled. The unch......the nuclear area, where genetic expression occurs, promoting infection. Such insights--illustrated in real-time movies created by scientists of the Ludwig-Maximilians-Universitt Mnchen--may set the stage for better anti-viral drugs, or for delivering gene-therapy medicines directly to the cell nucleus. "For th...Enzyme mimetic reduces tissue damage in colitis animal study
...istence of inflammatory bowel disease in humans by promoting infiltration of inflammatory cells (neutrophils) into the intestine wall. Inflammatory bowel disease includes two specific disorders: Ulcerative colitis, which affects the inner lining of the lower colon, and Crohns disease, which extends into the de...