Yale researchers shed light on B cells involvement in autoimmune diseases like lupus
...d. The researchers used a strain of mice that were prone to autoimmune diseases to visualize autoreactive B cells. They found that the autoantibody reaction does not take place in the germinal center as previously thought, but in an unusual area of the spleen. The team also demonstrated that somatic hyper...University of California, Riverside study dates our ancestors
... which resulted in relatively firm substrates less prone to resuspension. Close inspection of these fossils could help determine exactly when bilaterian animals emerged, a topic of much controversy. "There have been reports of trace fossils as old as 1 billion years old," said Droser. "But these records ar...Researchers discover new risk factor for colon cancer
...ed the BLM mice with another type of mouse that is prone to developing intestinal cancer. When they counted the number of intestinal tumors in the offspring, they found that mice carrying one Blm gene mutation developed twice as many tumors as mice without the mutation. In another experiment, the resear...Personal body part grown in a dish
... devices are often implanted. These are expensive, prone to mechanical failure and can cause infections, says Wessells. "Plus it's not natural by any means."...Targeting enzymes that immortalize cancer cells: if you can't turn them off, round them up
...hose with DKC develop skin lesions and anemia, are prone to life-threatening infections, and frequently die from bone marrow failure. Those who survive into their twenties or thirties often die of cancer. Telomeres were recognized as chromosome end caps in the early 20th century, but it wasn't until 1982 t...Hope for nano-scale delivery of medicine using a light beam to move liquid through tiny tubes
...hallenge. Also, any real-life application would be prone to operational problems, such as clogging of the pump or valve by tiny molecules." Garcia, and colleagues Devens Gust and Mark Hayes, professors in the ASU Department of Chemistry & Biochemistry, have combined their bioengineering and chemistry skill...Tomorrow's super robots may owe their mobility to a cockroachs legs today
...levision model, would always be stiff, clumsy, and prone to breakdown. This was before the advent of "Biomimetics," a research aimed at developing a new class of biologically inspired robots that exhibit much greater robustness in performance in unstructured environments than today's robots. This new cla...Transplant patients from 40 years ago cause Pittsburgh doctors to take an about-face
...recipients of the small bowel, an organ especially prone to rejection, are taking a single anti-rejection drug and only once or twice a week, University of Pittsburgh researchers reported today. Many kidney, liver and pancreas transplant patients being treated under the new philosophy, introduced last year...Other highlights in the August 21 issue of JNCI
...llin have increased angiogenic potential, are less prone to cell death, and have elevated levels of proteins involved in cancer signaling pathways than cells that do not overexpress the protein. The researchers conclude that "adrenomedullin may make an excellent biologic target for developing intervention ...New signaling pathway found, may be linked to movement disorders
...nts such as cocaine and amphetamines and were more prone to drug-induced seizures. The investigators also examined the animals' brains. When they disabled the gene for FGF14, the team had ensured that a fraction of the protein remained intact and replaced the rest with a protein that appears blue when expo...Monkeys that drink heavily develop signs of liver disease, Wake Forest study shows
...e are heavy drinkers, who become intoxicated, most prone to changes in the liver. "In some respects, this group of monkeys mimic the human situation," he said, except "we don't have any monkeys that don't drink any (alcohol) -- they all drink something." First, Cunningham and his colleagues in the Cente...Findings show exceptional longevity runs in families
...d 70-year-old children of centenarians may be less prone to cardiovascular disease because they have high levels of HDL ("good") cholesterol and low levels of LDL ("bad") cholesterol. Identifying and characterizing these and other familial patterns are key steps in understanding the role of genetic, enviro...Drug breaks for HIV-infected individuals may put certain immune cells at risk
..., HIV-specific CD4 cells appear to be particularly prone to infection by the virus during treatment interruption. Infections of CD4 cells hasten their destruction and help spread the disease to other cells in the body. In time, as the patients immune system is progressively weakened, this can give rise to ...Stanford researchers shine light on new genes involved in multiple sclerosis
...se model. In one, he created a mouse line that was prone to developing MS but lacked a gene that was overexpressed in chronic MS. These mice had fewer signs of the disease during the chronic phase than the MS-prone mice that still had the overexpressed gene. He also injected MS-prone mice with a protein fo...Control of intestinal inflammation by PGE2 and its receptor
...hn disease, conditions where the gastric mucosa is prone to inflammation and tissue damage....New material to patch injured knee ligaments
...rt to surgery. But afterwards it can be weaker and prone to further injury. So Volker Musahl and his postdoc Savio L-Y Woo at the University of Pittsburgh in Pennsylvania tried patching up MCL injuries in rabbits with the material derived from pig gut. The patched ligaments were stronger than those left t...Adhesive interactions in contact dermatitis
...rry mutations in the corresponding human gene, are prone to bacterial infection. Grabbe et al. now report that in a mouse knockout model lacking CD18 entirely, animals are unable to mount the usual inflammatory responses to allergens. At the cellular level, the defect is specific for the extravasation of T...New research findings offers possible clues for avoiding sudden infant death syndrome (SIDS)
...espite the established increased risk of SIDS with prone sleep, the cause of death is still under debate. O...1 were born at term. At home, 4 (19 percent) slept prone or face down, 4 (19 percent) slept supine (face up) or on the side, and 13 (62 percent) slept supin......stellar cluster with many large, short-lived stars prone to producing supernovae had passed near Earths solar system several million years ago. That discovery, made by co-author and Space Telescope Science Institute astronomer Jess Maz-Apellniz, led Bentez to check the scientific record for potential eff...... humans. In dogs, several larger breeds are most prone to arthritis: golden retrievers, Labrador retrievers, German shepherds, Newfoundlands and St. Bernards. Conversely, certain breeds that have long been bred for speed or athletic prowess, such as performance borzois and racing greyhounds, almost neve...