New NIST procedure seeks improved diagnosis of Fragile X syndrome
A robust protocol for measuring a specific class of genetic elements...expansion of these trinucleotide repeats. The NIST protocol responds to the guidelines recently issued by the American College of Medical Genetics, which recogn...Gender differences in fatigue explained by the use of the body's aerobic pathways
...ared the fatigue produced by an identical exercise protocol in men and women under two different conditions: a control condition and an ischemic condition, where blood flow (and thus oxygen) to the muscle is cut off by mechanical compression. If gender differences in fatigue exist and are due to an "oxidativ...ORNL technology gets nod from EPA
...fies testing and lowers the cost. And the new test protocol eliminates the problems associated with drawing samples, shipping them, and logging those samples and results. "When you have to move samples off site, there are just that many more opportunities to make mistakes," Jenkins said. In addition to enviro...Hypoglycemia may affect newborn's brain cell function, says Hopkins researcher
...ptor activity in neurological experiments. Using a protocol approved by the Institutional Animal Care and Use Committee at MCP Hahnemann University, the research team sustained hypoglycemia in piglets (3 to 6 days old) for two hours with insulin injections. Researchers then extracted brain tissue from six hyp...Other highlights in the Feb. 6 issue of JNCI
...ood reason to deny fit, elderly patients access to protocol therapy. They add that these results highlight the need for more elderly-specific clinical trials to examine the unique physiologic needs of the elderly population. This research appears in the Feb. 6 issue of the Journal of the National Cancer Inst...Respiratory activation in patients with obstructive sleep apnea syndrome (OSA)
...e second night (N2) study, which followed the same protocol as the first night study. Sham study. Seven patients had a third study during which the CPAP was reiterated to suboptimal pressure (mean = 5 1.4 cmH2O). The pressure was maintained throughout the study night without any hypoxic periods. Wakefulnes...Nuclear medicine aids early diagnosis of pulmonary anthrax
... Food and Drug Administration (FDA) has approved a protocol for a clinical trial to assess the efficacy of a 99mTc-labeled monoclonal antibody in imaging early-stage inhalation anthrax infection. According to the representatives of the company that has developed the monoclonal antibody, the technique offers ......nd several subsequent surgeries following the same protocol have shown that the laser is a superior instrument for such an operation. Another center development with significant medical potential comes from the X-ray portion of the spectrum. Experiments with the FEL beam have shown that it is possible to pr...Kyoto's global warming controls could harm forests
..., in the June issue of Conservation Biology. "The protocol could easily do more harm than good unless accompanied by strong incentives to protect biodiversity." While the U.S. commitment is now in doubt under the Bush administration, the government had planned to meet half its annual commitment throug...Georgetown researchers achieve increased cancer patient survival
...ed in a combination regimen known as a prime-boost protocol in late-stage cancer patients. Five of nine patients treated with sequential vaccinations of vaccinia-CEA and ALVAC-CEA (VAAA) not only showed increased immune responses, but also remained alive two years out compared to zero long-term survivors in ...New finding accelerates discovery of disease genes and human population history
...rged from a large-scale experiment using a uniform protocol looking at 19 randomly selected regions of SNPs all along the human genome," says David Reich, first author on the paper. The results suggest that at least in northern European populations, the blocks are as much as 8 times larger than previously th...Pooling worldwide data about childhood tumors helps researchers gauge aggressiveness of treatment
...ting high-risk neuroblastoma. The tandem treatment protocol achieved survival rates (after three years) of 60 ...ll conduct a larger study of the tandem transplant protocol for high-risk neuroblastoma, with Dr. Grupp as the principal investigator. Pooling the Expertise of ...Researchers discover the ultimate adult stem cell
...the bone marrow were isolated and purified using a protocol developed by Dr. Sharkis. Bone marrow cells from male mice were spun in a centrifuge, partitioning cells according to their weight in a process called elutriation. Then the cells belonging to one of the partitions were exposed to a panel of antibodi...New study locates genes that may predict alcoholism, depression
...d States in which investigators have used a common protocol to gather clinical and biological data from several hundred families with more than one case of alcoholism. "With this new data we can now take a better look at patterns of diagnoses such as alcoholism and depression that run in families," said John...Three genetic steps convert normal mammary cells into breast cancer cells
...en converted into breast cancer cells by a defined protocol of genetic changes. In the January 1 issue of Gen...t cancer. Therefore, this in vitro transformation protocol did not only produce malignant mammary cells, but did also initiate a process of additional events w...Genes reveal new clues about the first flower
...eel they have developed a more powerful analytical protocol for getting more accurate estimates of any given piece of evolutionary history. "The strongest conclusions can be drawn from congruent results based on clean data from different sources of genetic material analyzed with different analysis methods," ...Simpler HIV drug regimen may improve results, Science study on monkeys suggests
...his is the first structured treatment interruption protocol that gives a potential recipe for how to treat patients. Every clinical center could follow this protocol," said Lisziewicz. Twenty-one weeks later, both groups of monkeys on treatment were controlling the virus successfully. The animals had similarl...Searching for the secrets of drug-free transplants
...nder the supervision of physicians. "Our weaning protocol involves a very conservative and closely monitored step-wise process. Under most other circumstances, discontinuing anti-rejection therapies could have devastating effects for the patient," explained Dr. Mazariegos, assistant professor of surgery at......n response, Cornell lab scientists developed a new protocol to help FeederWatchers collect information about the mysterious new disease. From this evolved the House Finch Disease Survey. "Fortunately, we were in position to act quickly and therefore had an unprecedented opportunity to monitor a wildlife d...... putting these concepts into practice to develop a protocol for optimizing stocking densities for reservoir sportfishes. As a dedicated angler, he looks forward to the time when he can devote his full energies to personally reaping the benefits of enlightened fisheries management. Ney's colleagues know him as...