New gene therapy tool successfully treats mice with hemophilia A
.... Conventional approaches to gene therapy have not proven successful against hemophilia A, partially due to ...ntreated hemophilia A mice. "If the technology is proven effective in humans, it would provide a more permanent treatment for hemophilia A." According to Dr...DuPont to launch soybeans into space
...ULTURETM technologies developed by WCSAR that have proven successful in growing other plants in space.ASTROCULTURETM controls the input of variables and conditions necessary for plant growth such as temperature, water, humidity, light, atmospheric conditions and nutrients. This program also provides an exc...Implant may stabilize schizophrenia patients' treatment
...ay work for up to a full year. The device has been proven effective in initial laboratory studies, and more research is underway (in collaboration with the University of Pittsburgh School of Medicine) to lead to potential clinical trials. Findings from the small-mammal study appear in the current issue of t...Foreign DNA makes TB vaccine better
...hod of vaccine delivery works well in mice, it has proven to be a challenge in both non-human primate and human studies. One of the reasons DNA vaccination has not been effective in humans or in primate models may be due to the low amount of protein produced, or, put another way, the high amounts of DNA nee...Chimpanzee stone tool site excavated
...rd of their tool using activities. Archaeology has proven a reliable, efficient, and feasible method to uncover past chimpanzee activities in the rainforest. This type of archaeological application is useful in reconstructing past primate behavior both human and non-human. The results open a new territory f...New program helps protect Asian elephants through crop-raiding prevention
...waiting in their gardens to fend off elephants has proven unproductive and dangerous," added Arnold Sitompul, co-manager of the WCS Sumatran Elephant Project. "By having a roster of guarding duty, the time a farmer spends guarding his fields will be reduced and he will be part of a co-ordinated effort rathe...Vitamin C transporter gene discovery in mice
...ve implications. We have more work to do. The only proven human requirement for vitamin C, or ascorbic acid, is to prevent scurvy, a disease characterized by bleeding gums, anemia, skin hemorrhages, and death, first discovered in 18th century maritime sailors when their diet was found to be deprived of vita...Gene study determines how humans are related to fruit flies and nematode worms
...ed on the weight of the evidence, rather than as a proven fact. It is always better to keep an open mind about these things, not to become married to one hypothesis or another, and to let the data speak for themselves." This research was supported by the National Aeronautics and Space Administration (NAS...Anticonvulsant drugs found to impact on epileptic childrens ability to recall information
New Orleans -- Epilepsy and its treatment have proven to impair cognitive and behavioral functions. The impact on the former by epilepsy associated seizures, brain damage, and use of anticonvulsant drugs can result in memory deficits, attention problems, and reading and writing difficulties. About tw...Mathematical analysis could aid flu vaccine selection
...ibuted around the country. These predictions have proven to be largely accurate and the resulting vaccines are credited with saving millions of lives. In some years, however, the vaccine has not targeted the strain that turned out to be most active. In a paper published in the April 23 online edition of th...Scientists identify DNA flanking region as trigger for genetic instability
...he DNA triplets to repeat too many times. "We have proven for the first time that there is something in the flanking DNA sequence that is triggering the genetic instability. These flanking regions effectively drive the mutation. Such flanking regions are a possible new therapeutic target for treating, or pr...UMass microbiology team probes bacterium's surprising survival tactics
...an area and removing the soil a process which has proven to be both expensive and inefficient, Lovley said. Geobacters dont actually remove the uranium, explained Lovley, but they do transform the metal from a soluble form to an insoluble form, so that it is no longer able to leach into the groundwater and...Microbiology team probes bacterium's surprising survival tactics
...n area and removing the soil - a process which has proven to be both expensive and inefficient, Lovley said. "Geobacters don't actually remove the uranium," explained Lovley, "but they do transform the metal from a soluble form to an insoluble form, so that it is no longer able to leach into the groundwater...New tool speeds study of mammalian protein function
... and coworkers used, RNA interference, had already proven its general utility in other non-mammalian systems, like the fruit fly, and in plants, fungi, and the worm C. elegans. In these organisms, double-stranded RNA injected into cells inhibits the synthesis of protein made by the gene that matches the inj...New evidence on revolutionary brain pacemaker for Parkinson's Disease patients
... be considered experimental in any way as it has a proven safety and efficacy profile over this period. EU approval in 1998 and FDA approval in the USA in January 2002 were milestones in the development of this therapy that can transform patients lives for the better. This evidence has also helped to identi...Scientists develop markers capable of detecting minute numbers of cancer cells in blood
...rs were able to differentiate between samples with proven metastatic deposits and those that were free from cancer. Our results further indicate that, although individually these genes are capable markers for metastatic disease in breast cancer, their sensitivity and specificity are greatly enhanced when u...Rush opens tissue and cell lab to produce cellular products
...own cells to treat cancer -- is increasing and has proven to be very successful."Equally important, the Rush facility will comply with federal Food and Drug Administration's (FDA) new standards for Good Manufacturing Practice (GMP) and Good Tissue Practices (GTP). Referred to as a "clean room" facility, ul...Researchers identify immune response to tuberculosis infection
...ccine created in 1908 and first used in 1921 has proven successful in protecting children from the disease, but has had varied effectiveness in adults. In the new study, lead author Zheng Chen, M.D., of the BIDMC Tuberculosis Research Unit and colleagues used macaque monkeys to study the nature of the imm...Scientists combine therapeutic cloning, embryonic stem cells, and gene defect in mice
...ned forces to work on a problem that until now has proven difficult to overcome. Scientists have been able to use nuclear transfer to create embryonic stem cells and differentiate them in culture to create many different cell types, including muscle, neurons, and hematopoietic stem cells, which are the prec...Genetic clues for finding and treating cardiovascular disease (CVD)
...anding the human genome. The Zebrafish has already proven its value by pinpointing a variety of heart mutations that may eventually explain congenital human heart disease. The florescent, see-through Zebrafish is comprised of bright-green organs. This colorful workhorse may someday lead researchers to uncov...