New method is first to mimic subtle genetic changes
A new research technique has proven to be a potent tool for predictably altering gene expression in mice without disrupting the regulatory elements that are essential for normal gene function. The research, published in the April Developmental Cell, may prove to be invaluable for futur...'Knock out' rose receives Texas superstar and earthkind designation
...pesticides of any kind were ever applied. "It has proven to be almost resistant to black spot, the fungal disease that is the scourge of roses across much of the United States," said George. "It is also resistant to powdery mildew and aphids. It is cold-hardy throughout the state and will grow in a wide ra...Germany starts clinical development of a new tuberculosis vaccine
...TB pathogen, Mycobacterium tuberculosis. BCG has a proven safety record for many decades, but unfortunately it lacks effectiveness," notes Kaufmann, adding that children can be protected against certain forms of TB only. There is no protection at all against pneumotuberculosis, by far the most common form o...Device detects, traps and deactivates airborne viruses and bacteria
...ft x-rays with a conventional corona that has been proven to be very effective at charging and trapping particles in a range of sizes. On the walls of the device, Biswas has coated nanoparticles that catalyze the oxidation. These nanoparticles are "smart" objects that are turned "on" and "off" by irradiati...Schering-Plough scientists identify protein essential for cholesterol absorption from intestine
...and exercise has been inadequate. ZETIA has been proven to significantly improve LDL cholesterol levels. The effects of ZETIA, either alone or in addition to a statin, on the risk of cardiovascular morbidity and mortality have not been established. ZETIA is a prescription medicine and should not be take...Risk and food are on the same plate: World food safety experts offer new methods to assess risk
...ystems of testing and release of products have not proven very effective in reducing foodborne illness." Risk assessments are the gathering of quantitative data on the prevalence (whether it occurs) and concentration (how much is present) of foodborne illness for specific foods. Modules from farm to fork he...National ocean commissioners & scientists call for overhaul of ocean policies & management
...may sound logical and obvious, implementing it has proven elusive. In the Pacific Northwest, salmon have suffered because of piecemeal management. Conservation of salmon species requires an understanding of the ecosystems and resources they share with many other living things, including humans. Historicall...Researchers-again-pinpoint why stress kills
... string of scientific reasoning for matrimony is a proven fact: the prevalence of depression in patients with coronary artery disease (e.g., myocardial infarction and heart failure) is approximately five times that of the general population. Background Major depression is a significant predictor of mortal...New evidence points to pollution as main cause of much coral reef destruction
...ining the main cause or causes of this decline has proven a much more contentious issue. In the current edition of the Journal of Experimental Marine Biology and Ecology (JEMBE), Harbor Branch marine scientist Dr.Brian Lapointe and colleagues present new evidence they hope will help settle one major debat...Researchers discover that a virus can naturally target and kill tumors
...hat makes a protein called IL-12. This protein has proven to be a good cancer killer but is also toxic to normal tissues. By putting the IL-12 gene into Sindbis, the gene was only activated after it had been carried into cancerous tissues by the virus. The combination was even more effective than Sindbis al...New mode of action discovered for tamoxifen
... treatment protocols." Although tamoxifen has been proven clinically effective at treating and, in some cases, preventing breast cancer, this drug has two significant problems. Long-term use of tamoxifen, like many other cancer drugs, can lead to drug resistance and tamoxifen often causes unpleasant side ef...Sex in the brain: How do male monkeys evaluate mates?
...- A pint-sized, tree-dwelling Brazilian monkey has proven to be strikingly similar to humans when it comes to sexual responses, a national research team has discovered. Through functional magnetic resonance imaging, or fMRI, scientists from the University of Wisconsin-Madison and collaborating institutions ...A killer microbe as a living antibiotic
...to identify the targets in the prey cell that have proven to be successful points of attack in this million-year-old prey-predator relationship. The lytic enzymes acting on cellular systems that are not targeted by conventional chemical antibiotics are thereby especially interesting. Far reaching anti-mi...Space technology in new technique to fight breast cancer
...challenges have already been overcome. "HIFU is a proven intervention technique for the ablation of cancer cells in the human body," explains Brunsveld van Hulten. "This technique combined with the recent advances in MRI capabilities that can provide a proper real-time view of the area during treatment, wi...Asthma could be several diseases masquerading as one
...r genes associated with asthma, which has, so far, proven difficult. Different phenotypes could be influenced by different genes, said Wenzel. If so, then searches focusing on specific patient subsets might uncover stronger genetic influences in asthma. ...AGU journal highlights - 6 January 2004
...ants absorb atmospheric nitrogen Researchers have proven for the first time that vegetation candirectly absorb atmospheric organic nitrogen. Sparks et al. reportthat plant leaves can remove organic forms of nitrogen, which couldhave a significant effect on atmospheric carbon and nitrogen cycles.The authors...Regenerative chemical turns muscle cells into stem cells
...ction of foreign cells. However, in general it has proven very difficult to isolate and propagate stem cells from adults. Embryonic stem cells (ESCs) offer an alternative, but face both practical and ethical hurdles associated with the source of cells as well as methods for controlling the differentiation o...DFG to establish seven new Clinical Research Units
..., the programme centres on supporting particularly proven groups of researchers by appointing a new leader for this group. On the other, it aims to promote innovative research projects at medical faculties. The funding is scheduled to run for six years. It particularly supports young researchers and makes a...Mouse embryonic germ cells and male gametes created in the lab
...c stem cells. However, these eggs so far have not proven capable of being fertilized by sperm. Daley's team worked on the other side of the reproductive equation, creating male gametes, or primitive male sperm. The researchers used the same embryoid bodies that generated the embryonic germ cells, but th......e rigorous high-fat, low-carbohydrate diet already proven to reduce or eliminate difficult-to-control seizures in some patients. The common elements in both diets are high fat and low carbohydrate foods that alter the body's glucose chemistry. The ketogenic diet mimics some of the effects of starvation, in...