Tag: "proves" at biology news

MS clinical trials confirm approach, demonstrate need to carefully refine targeted peptide therapy

...ng, the increase in brain lesions in some patients proves that MPB can induce an immune response in MS and is therefore a good target for MS immunotherapy, the researchers say. "There is no longer any doubt in my mind that MBP is one target autoantigen (a protein that triggers an immune response) in MS," s...

Gene found to contribute to deadly form of breast cancer

...y help explain why it grows, spreads and sometimes proves deadly so quickly. The finding, published in the Oct. 15 issue of the journal Cancer Research, confirms the team's earlier suspicions that a gene called RhoC GTPase is a key factor in inflammatory breast cancer. Just over a year ago, they publishe...

UCSF team reveals how the most selective of all cell gatekeepers works -- a 'three-faced' channel vital to most human organs

...ed in the October 20 issue of Science. The finding proves that when it comes to controlling access into the cell, size isn't everything. Chemistry is. The researchers were able to determine the chemical interactions that enable the channel to allow some simple carbohydrates free passage, yet block access to...

Finding could lead to new approach for treating severe heart disease

...eceptors, through which VEGF proteins act. If this proves to be the case, the reverse would also be true - the higher levels of oxygen in healthy tissue would induce fewer VEGF receptors, thus diminishing the activity of VEGF proteins and the induction of angiogenesis. The levels of VEGF gene expression in ...

Livermore research team wins distinguished Department of Energy award for development of miniature glucose sensor for diabetes patients

...y director for Science and Technology. "This award proves the Laboratory continues to make significant contributions that benefit the quality of life." The Bright Light Award is part of DOEs Energy 100 list, which honors 23 years of the best scientific and technological accomplishments the Department of E...

Cancer's penchant for developing drug resistance is a result of chromosome reassortment, UC Berkeley scientist proposes

...y, when a cancer becomes resistant to one drug, it proves to be resistant to others that are structurally different. Scientists have had a hard time explaining this as the result of genetic mutation and have suggested various hypothetical scenarios, including mutator genes and multidrug resistance (MDR) gen...

Enzyme is key to hallmark of Alzheimer's-- moves to block it underway

..., which would squelch plaque production. "If that proves therapeutic," he says, "physicians might ultimately give AD patients a "cocktail" of various enzyme-blockers or blockers along with vaccines. "Both approaches may prove useful in treating Alzheimer's," Wong explains. Beta-secretase works by trimming...

University of Florida researchers identify a protein that may induce drug resistance in lung cancer cells

...ssociation between the protein and drug resistance proves to be a widespread phenomenon, it could be the focus of wider research and clinical applications....

UCLA geneticists identify cause of malformed genitalia, finding will improve sex assignments in ambiguous newborns

...T-4 duplication prenatally," Vilain said. "If this proves true, in the future we may be able to correct the defect in the womb and restore the embryo to its original male status. This may repair the genital malformations before the child is born."...

Proteins in African HIV strains interact differently with drugs

...ent along their entire genome, and this new report proves that variation can affect interactions between drugs and HIV proteins at a very basic biochemical level. We need to broaden drug development efforts to include these subtypes." For the research, Freire's group created recombinant forms of the proteas...

Secret channel holds key to metabolic mysteries

...s another surprising characteristic -- removing it proves 100-percent lethal to cells." This is a further indication that the researchers are onto something important, because lethality shows that the gene is somehow essential to every cell's life. The Nature paper is important in part because it will sti...

Aspirin targets key cell that triggers organ rejection and other immune responses, report University of Pittsburgh researchers in journal article

...esent antigens. Among other things, this finding proves that aspirin does not have a toxic effect on dendritic cells, the authors note....

UCSF scientists halt tumor growth by manipulating telomerase enzyme

...extracted directly from patients.) If the strategy proves viable, one possible therapeutic approach, says Blackburn, would be conducting gene "anti-therapy," as was done in the current study. Another would be using an as yet-to-be-identified "small molecule" drug that could warp telomerase and mimic the mut...

UCSD biologists identify genetic mechanism conferring resistance to 'Bt toxins'

... gut. But this, at a molecular level, conclusively proves it." The UCSD teams discovery also sheds light on the puzzling and sometimes contradictory findings of previous attempts to pinpoint a mechanism for the development of Bt resistance in insects. "For a couple of decades now," says Griffitt...

Russian, PNNL scientists advance US seed production, oil remediation

...nproliferation product lines. If either technology proves effective, Dye Seed could patent the product in the United States, and the Russians would control patents in Russia and the Newly Independent States. Business inquiries on this or other PNNL technologies should be directed to 1-888-375-PNNL or e-mail...

UCLA neurobiologists identify brain cells that control breathing

...people with breathing disorders. If his hypothesis proves correct, Feldman may find fewer or dysfunctional neurons in the brains of people with breathing disorders....

Mothers transmit DNA through daughters only

...eds or thousands of generations. In practice, this proves impossible. A new idea posits to compare the inheritance of mitochondria with some other genetic material that is transmitted through females only. If the pattern of inheritance is identical, this evidence stable maternal inheritance of the mitochond...

Initiative considers changing face of biology

...99.9 percent of their DNA, and they have said that proves that race has no meaning. Yet, the genome has produced new fields such as pharmacogenomics, which is working to produce ethnically and racially targeted pharmaceuticals....

African bone tool discovery has important implications for evolution of human behavior

... than 70,000 years old. The discovery conclusively proves that human use of formal bone tool technology is more than twice as old as the previously accepted dates. The advent of bone tools was a major development in human tool technology and is considered by many archaeologists to be a key indicator of "beh...

Paradox of groundwater age has implications for hydrology

...ive isotopes to age-date groundwater. If a sample proves to be very old, we might conclude that it has been migrating very slowly through the aquifer, Johnson said. However, the water may have migrated quickly, and only appears very old because of the effect of the surrounding aquitards. Such a situation ...

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