Doublecortin : A Novel Gene Involved In Cortical Development
... team from College de France. Technicalsupport was provided by the Genethon and financial supports by the FondationJerome Lejeune and by Association Francaise contre les Myopathies thanks toTelethon. A patent application was submitted by INSERM on 21 November, 1997. For more information : " Identification...Fruit Flies May Shed Light On Cocaine Addiction
...ugs. Extensive studieson rodents and monkeys have provided little information about the molecularprocesses that underlie cocaine's behavioral and addictive effects. Using fruitflies in such studies offers several advantages. The genetics of the flies havebeen intensively studied for 80 years, providing res...Genes May Affect The Response To Drugs That Treat Mental Illness
...rs. Further evidence supporting this hypothesis is provided by newfindings of association between polymorphisms in the promoter and codingregions of the 5-HT2A receptor and clozapine response. These results suggestthat 5-HT receptors are important for the therapeutic action of thoseantipsychotic drugs targe...Cellular 'Short Circuit' Causes Insulin Resistance
...ournal ofBiological Chemistry, Zick and colleagues provided a new insight intothe molecular basis of insulin resistance, a condition that can leadto diabetes. In insulin resistance, cells no longer respond toordinary levels of insulin. The scientists discovered that this mayoccur because some of the proteins ...Maillinckrodt Medical Licenses Invention For Concentration Of Rhenium Radioisotopes
...henium is needed for this type of procedure and is provided by a special ion exchange system developed at ORNL. Theconcentration method, developed by researchers at the laboratory, usesrhenium-188 for the radiation of the coronary arteries after angioplasty. Rhenium treatment following balloon angioplasty c...Scientists Work To Restore Native Fish And Habitat To Great Lakes
...for our programs" said John Christian. "The funds provided by Congress under the Great Lakes Initiative will help move us in that direction." As the nation's largest water, earth, and biological science and civilian mapping agency, the USGS works in cooperation with more than 2000 organizations across the co...Experimental Trial Combines DNA Vaccine With Triple-Drug Therapy To Stop HIV
...nation. Support for the clinical trial is provided by the National Institutes ofHealth, and the experimental vaccine for the trial is manufactured by ApollonInc., a biotechnology firm located in Malvern, Pennsylvania. The University of Pennsylvania Medical Center's sponsored research ranksfi...Gene Therapy Enables Transplantation Without Immunosuppressive Drugs
...r. Primary grant funding for this work was provided by the NationalInstitutes of Health. Additional support came from the Thomas B. McCabe Fund andthe American Heart Association. The University of Pennsylvania Medical Center's sponsored research ranksfifth in the United States, based on grant ......rtment of Entomology. Funding for the research was provided by American Museum of Natural HistoryTrustee Henry G. Walter and by Henry and Meryl Silverstein....Columbia Researchers Identify Gene For Inherited Baldness
...regrowth of hair, yetnone of these approaches have provided any relief without significant sideeffects. But, says Christiano, "Hair follicles, like all cells, have cycles.This finding is the first indication that we may be able to regulate that cycle,triggering the growth of new hair. It may be possible, for ...Good Ergonomics Is Good Economics
...cidents. Four very different kinds of products are provided here as illustrations of each of these beneficial ...e extensive ergonomic workstation improvements and provided proper lifting training for all employees. In the first year following the changes, workers compensa...... efforts in the mid-90s to map the ratgenome. This provided enough markers on the rat genome to begin to map theBelgrade rat and conduct the DNA analysis to find the gene that encoded thecritical protein. "The publication in 1995 of the rat genome inspired us to get togetherwith the Harvard gr...Low Cholesterol? Reduced Sodium? What Do These Terms Really Mean?
...(from USFDA, 1995). Procedure Participants were provided with a booklet and answer sheet. The first page of...present in one serving of the soup. The units were provided forthe subject on the booklet and on the answer sheet. At the conclusion of thesurvey, subjects were...Microsurgery Made More Accurate With Virtual Measuring Tool
...epth perception through retinal disparity cues not provided by monoscopic display systems. In spite of this, however, the problem of measuring absolute distances and dimensions remains. When combined with stereo-computer graphics, on the other hand, a unique measuring tool, the virtual tape measure, has been ...Technique Gives Researchers New Look At Genetic Activity In Living Cells
...ts to see entire chromosomearms. The results have provided pictures and proof of theorized chromosomalfibers 100 nanometers in diameter in live cells as folding and unfoldingoccurs. Belmont's group has seen specific bending and motion of chromosomal fibers. UCSF biologists have seen motion during mitosis in...... bloodvessels." Funding for the study was provided by the National Cancer Institute andNational Eye Institute of National Institutes of Health (which accounted forapproximately 50% of the funding) and Merck KGaA, Darmstadt, Germany....Washington University Licenses Its New Antibacterial Technology
... structure andfunction of microbial attachment has provided a blueprint for the development ofnovel antimicrobial therapeutics and strategies," Hultgren says. E. coli is covered with hair-like structures called pili. The tips ofthe pili carry proteins that fit into receptors in the kidney or bladder l...Plants Thrive With Insect-Induced Immune Responses
...nals totrigger an immune response -- those signals provided by the caged caterpillars. As the growing season proceeded, all of the plants were colonized by the normalinsect pests, primarily earwigs, green peach aphids and flea beetles. Agrawal observed the following effects of these pests: Plants ini...Induced Mutant Mouse Models Of Lipoprotein Disorders And Atherosclerosis
...have been produced in the mouse. This has provided insights into the genes possibly responsible for thesedisorders in humans and has allowed more invasive studies of the pathophysiologyof these disorders. The mouse as a species is highly resistant toatherosclerosis. However, several of the dislipidem......nd agricultural industry. The past two years have provided dramatic evidence of a lake in trouble: massivedie-offs of millions of diseased fish and hundreds of thousands of birds. Humanhealth warnings have been issued on several occasions as a result. Most expertsbelieve these problems are caused or exacerba...