Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
...ecognize that the connection of our study to human psychosis or schizophrenia is very tenuous," Dr. McKnight said. "It's difficult to draw direct parallels between the simple behavioral abnormalities observed in the mutant mice and the complex, delusional cognitive defects that characterize human schizophrenia...Small amounts of alcohol or anesthetics may damage the developing brain
...reissguth says. "But there also were high rates of psychosis and suicide attempts and almost half suffered from major depression." More basic work from Charles F. Zorumski, M.D., the Samuel B. Guze Professor and head of the Department of Psychiatry at Washington University School of Medicine in St. Louis, ano...Can EPO prevent loss of brain function in schizophrenia?
...ting for the various dysfunctions of schizophrenic psychosis are far from clear. Existing animal models of schizophrenia only reflect certain aspects of the human disease. Therefore, novel concepts to treating schizophrenia should be immediately translated into clinical pilot trials. This is particularly appro...Gene enhances prefrontal function at a price
...icated as a mechanism related to schizophrenia and psychosis in humans. Animal studies modeling possible brain mechanisms in schizophrenia have also observed this pattern. These val-influenced variations "slightly bias humans toward the expression of two biological phenomena associated with schizophrenia: abno...Implant may stabilize schizophrenia patients' treatment
...ve that may relieve many patients of the threat of psychosis and chronic social instability. "Schizophrenia destroys an individual's grasp of reality, robbing him of his identity and devastating his family," said Steven Siegel, MD, PhD, of the Division of Neuropsychiatry in Penn's Department of Psychiatry. ......ecific maternal infections with the development of psychosis in children. "The evidence shows some association...itself, a predictive factor for the development of psychosis in their offspring. Of the two major herpes simplex virus types, HSV-1 is extremely pervasive in th......ases that run in families, including some forms of psychosis and dementia. The scientists employed magnetic resonance imaging technology to scan a group of 20 identical twins, whose genes are identical, and 20 same-sex fraternal twins, who share half their genes. Using a high-speed supercomputer, they create......on, diminished reflexes, dementia, loss of memory, psychosis and mood disturbances. These macrobiotic subjects were somewhat unique because the parents of these Dutch adolescents were generally well-educated and of higher socioeconomic status. Of the macrobiotic adolescents who had tested B12 deficient the ye......deafness, solid tumors, a form of manic depressive psychosis for instance. A focus of interest are the 14 kno...r instance, two loci for deafness, a form of manic psychosis and several forms of cancer. In the context of Down syndrome, the scientists are hoping that the seq......rs investigatedwhether 5-HTTLPR is associated with psychosis by genotyping 50 schizophrenicor schizoaffective p... genotype had significantlyhigher BPRS ratings for psychosis than patients with the ls or ss genotypes.Examination of individual items revealed a specific signif...