Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...ng gap, then reseals the original DNA. The question is, how? Two theories prevail. According to the "one-gate" theory, DNA enters and exits the enzyme's active site through the same "gate." According to the "two-gate" theory, DNA enters by one "gate" and exits, after th...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...tion of TNF_ and then move forward to our original question ofhow TTP is involved in insulin's actions. This may turn out to be a genewith many different functions." David Lee, Wi Lai, and Michael Thompson of Duke and Hal Broxmeyer of IndianaUniversity School of Medicine also contributed to the research....New Discovery About Genes Has Implications For Genetic Therapy
...ion years ago. "We were interested in the basic question of how these introns insert themselves into different genes," Lambowitz explained. "We wanted to know where introns came from and how they move. "This class of introns appears very primitive, as if they were the ancestors of introns found in high......Spain). The medical literature, while skirting the question of Spanish fly's efficacy as an aphrodisiac, does chronicle an unfortunate side effect for human males: "erections douloureuses et prolongues," in the words of a French Foreign Legion physician who observed soldiers suffering painful, prolonged erec...DNA Techniques Allow Scientists To Become Pollution Detectives.
...he bayto oyster harvesting. "There's always been a question as to whether the bacteria wasnatural or manmade," Edmiston said. "There was never a way todifferentiate that before this research." Initial testing pointed the finger in both directions, the UFscientists found. "Both entities, human and animals were...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
... whichare designed to disable and devour them. The question is of increasing importancein acute health care. When bacteria invade the body, the immune system floods the bacterialcell with noxious oxygen and nitrogen-free radicals. The researchers found that when NO enters a bacterium, the N...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
... whichare designed to disable and devour them. The question is of increasing importancein acute health care. When bacteria invade the body, the immune system floods the bacterialcell with noxious oxygen and nitrogen-free radicals. The researchers found that when NO enters a bacterium, the N...NCAR Scientists Trek To Africa For Biosphere-Atmosphere Chemistry Study
...s may be affected by the perennial fires. "One big question we're asking," says NCAR/EXPRESSO field project leader Alex Guenther, "is whether the tropics serve as a net source or a net sink for carbon. Right now, we don't really know. One study won't answer the question, of course, but it will provide a start...Scientists Identify Retrovirus-Like Components In Corn Genome
...percent of the genetic material in a cell, but the question remained, "What are all those other things?" A Pur...niversity study of the corn plant is fielding this question and producing some surprising kernels of knowledge about the organization and makeup of genetic mate...BUFFALO, N.Y. -- The answer to the question of whether smoking increases a women's risk of developing breast cancer may lie in her genes, researchers at the University at Buffalo and the National Cancer Institute have found. Results of their study, the first to consider genetic variabili...Duke's Russian Laser Making Ultraviolet Light And Gamma Rays
...in protons andneutrons -- another major unanswered question in nuclear physics, Welleradded. Boosting gamma energies that high would require a major upgrade of the FELLaboratory's electron ring system. TUNL officials have already approachedthe Department of Energy about possible funding for what could then b...Siblicide In Nature: Study Of Galapagos Seabird Finds Death Can Ensure Species Survival
...n death from heat or patrolling mockingbirds. The question for Anderson, who first began examining siblicide ...ther," Anderson said. "Getting back to Darwin, the question is how could you maximize long-term reproductive success this way?" He found part of the answer in ...Scientists Identify Gene For Sexual Behavior In Male Flies
...st becontrolled in part by genes," Hall said. "The question is not whetherbut how do the actions of a given gene influence some interesting aspectof behavior." However, he said, "Even if a gene of this sort could be identified inhumans, that does not mean it would solely 'determine' behavior. Bydefinition, th...Molecular Imposter Rebuts Long
...nzymes that copy it. This finding brings into question decades of dogma on DNAreplication, says researcher Eric Kool of the Universityof Rochester. Kool adds that the new information may helpresearchers develop new drugs that are better able to sneak inand kill sickly cells -- including deadly cancer cel...Enzymes Targeted As Key To Understanding Drug Interactions
...ghlighted the problem of pharmacists who failed to question prescriptions for dangerous drug combinations, and pharmacists complain of computer programs that fail to give them adequate warning of possible interactions. A notorious example of a potentially deadly drug duo was Seldane, a popular antihistamine,...New understanding of crab populations may not bring fishermen's delight
...ying to figure out what drives the big swings is a question thathas taunted researchers for years. In fact, one of the most important andfiercest debates in population biology swirls around whether populationsgo through boom and bust cycles primarily because of internal ways of regulatingtheir numbers by chan...Ozone 'Chat Room' Provides Real-Time Air-Quality Research
...ns. But where is it coming from? Answering that question is a major quest of the OTAG air quality workgroup, and through this new approach to environmental research, Husar and Schichtel have been able to reach some tentative conclusions that implicate their own region, the Midwest. Also, they are seeing n...Merging Physics And Neuroscience: First Evidence Of Self-Organized Criticality In Brain Networks
...pears to bethe natural state of brain tissue. The question is what happens ifthere is something wrong with the tissue." Phenomena May Provide Clues to Disease Processes Preliminary study of brain tissue removed from epilepticpatients suggests that diseased tissue may in fact produce wavepatterns that are ...Summer Science: Firefly Babies Advertise Their Bitter Taste, UD Researchers Say
...n times in a row. "Our study answers a fundamental question that entomologists have been ponderingfor some time," Tallamy says. It also suggests an interesting topic fordiscussion between parents and children, he adds.......cellsthroughout the body, including the brain, one question scientists would like tobe able to answer is why the aggregations occur only in selected populations ofneurons. How and why do the proteins accumulate in the nucleus, instead ofpassing back and forth into the cytoplasm across the nuclear membrane? Ho...