Stanford Synchrotron Radiation Lab receives $6 million grant to decipher protein structures
... with heretofore unprecedented speed. "Synchrotron radiation research provides major opportunities for understanding the structure and functional relationships of genes," says Jonathan Dorfan, director of the Stanford Linear Accelerator Center that oversees SSRL. "SSRL has a well-established and growing progra...Major new initiative to resolve structure of protein families
...s, days, or even hours. "The use of a synchrotron radiation source such as the ALS can dramatically decrease the time required to solve novel protein structures," Kim has said. "It makes a clear and compelling case that protein crystallography can provide a foundation for structural genomics." As a major pa...Treatment protects mouse ovaries from radiation therapy
... the destruction of ovarian egg cells (oocytes) by radiation therapy. The report in the October issue of Natur...n known that treatment with chemotherapy drugs and radiation therapy can accellerate the death of oocytes, resulting in premature menopause and infertility among...UCSF Comprehensive Cancer Center program triumphs
...ay, PhD, UCSF professor of laboratory medicine and radiation oncology, leads a breast cancer SPORE, now in its eighth year of funding. The UCSF prostate SPORE supports six programs, which include an investigation of why some prostate cancers resist therapies aimed at reducing the growth-promoting effects of t...Studies at UNC plumb tumor resistance to treatment
... oxygen are relatively resistant to the effects of radiation treatment," said Mahesh Varia, MD, professor of radiation oncology at UNC-CH. "More recently we have learned that some hypoxic tumors are resistant to chemot...... explanation for why some cancers are resistant to radiation therapy. The finding is published in the current i...McCormick's lab, why some cancers are resistant to radiation therapy. Irradiation damages a cancer cell's DNA, and the theory behind its use is that, in the face...Tumor cells made more sensitive to radiation by blocking a key cellular molecule
...aking tumor cells more sensitive to destruction by radiation therapy. This was accomplished in colorectal tumo...py or radiation," said Joel E. Tepper, MD, head of radiation oncology at UNC-CH School of Medicine and a member of UNC Lineberger Comprehensive Cancer Center. "B...Fugu fish sequencing project potential boon to gene hunters
...mandate to study the genetic and health effects of radiation and chemical by-products of energy production. Said Trevor Hawkins, deputy director of the JGI, "This project will represent our single largest genome sequencing project to date and be the centerpiece of our new Genome Portal." Based in Walnu...... basis due to environmental factors, such as solar radiation and exposure to certain hazardous materials, as well as natural cell processes. This damage can leave chaos in its wake, scrambling or deleting the genetic letters encoding an organisms traits. If left unchecked, the mutated DNA will continue to repl...... protection, since nowhere on Earth is ultraviolet radiation strong enough to damage DNA so badly. However, severe desiccation can harm DNA just as much as UV radiation does-and the Antarctic is very dry, because all the water is frozen. "At the South Pole, the repair ...Unprecedented fire season in southern Africa aids air quality, climate change research
...o offset that warming by scattering incoming solar radiation back into space." The thick haze also contained high levels of ozone, a component of smog, that frequently reached levels similar to those found during air pollution alerts in major U.S. cities. Making the first balloon-borne measurements of ozo...Long-term data on Dendreons Mylovenge vaccine presented at American Society of Hematology
...e side effects associated with the chemotherapy or radiation treatments they have received for their disease. The therapeutic vaccine Mylovenge is designed to trigger the body's immune system to recognize and destroy cancer cells. It involves isolating dendritic cells from a patient's blood and activating t......n of drug therapies, but some patients may receive radiation therapy, bone marrow transplants or surgery. Proteasome Inhibition In normal cells, the ubiquitin-proteasome pathway is responsible for the orderly breakdown of multiple proteins and thereby helps to define protein turnover rates. Proteasomes......he "known" category. Broad spectrum ultraviolet radiation whether from the sun or from lamps and sunbeds is...tion about the separate wavelengths of ultraviolet radiation so each is separately proposed for listing as "reasonably anticipated to be a human carcinogen." ...... of Rituxan (250 mg/m2) and ZEVALIN (at a standard radiation dose of 0.4 mCi/kg of patient body weight) on day ...100,000 and 149,000/mm3) with ZEVALIN at a reduced radiation dose (0.3 mCi/kg). The overall response rate in 30 patients was 67 percent with 10 patients (33 perc...Something's fishy with Columbia chinook: females carry male's genetic signature
...is among the healthiest. The researchers ruled out radiation as a possible cause of the apparent sex reversal but suggested environmental contaminants that mimic hormones or water temperature changes could be the culprits. The research by University of Idaho and Washington State University scientists in cooper...Advisory panel on federal report on carcinogens makes recommendations to NIEHS/NTP for new listings
...in their jobs. -- Broad spectrum ultraviolet (UV) radiation from sunlight or artificial sources. However, the individual classes UVA, UVB and UVC were recommended for listing in the different category of "reasonably anticipated to be human carcinogens" because of difficulties in separating overlaps between c...NASA space technology shines light on healing
...ul mouth ulcers caused by cancer therapies such as radiation and chemotherapy. The treatment is quick and painl...possible cell damage caused by exposure to harmful radiation and weightlessness during long space missions.......t preserved specimen of a fossil from close to the radiation of all living birds discovered in over 100 years." The finding is the most significant from this part of the avian tree since the discovery of specimens of the closest relative to living birds, Ichthyornis, first discovered more than 100 years ago in......s finding indicates that a previously unrecognized radiation of small-bodied predatory dinosaurs spread across much of the southern hemisphere toward the end of dinosaur times, paralleling the Late Cretaceous radiation's of small-bodied theropods (such as dromaeosaurids and ornithomimids) in the northern hemis...