Tag: "rats" at biology news

Chemicals used to protect soldiers in 1991 Gulf War can damage testes, animal studies show

...ame conditions, Abou Donia and his colleagues gave rats equivalent doses to what the soldiers received. Wh...s, he found. The damage was even more severe among rats that were exposed to moderately stressful situations in addition to the chemicals. Results of the st...

A new study sheds light on how the tongue restores its ability to taste following surgery

...subsequent to unilateral CT section occur if adult rats are placed on a sodium-deficient diet. However, t...nd intact CT nerves by systematically varying when rats were placed on the low-sodium diet. Responses were recorded from both CT nerves starting at 50 days...

Without water, the body will shut down its need to ingest food

...ecessary for normal food intake, the team deprived rats of drinking water overnight while slowly infusing the water these rats normally drank into the stomach. Methodology In freely feeding Long-Evans rats, meals were separat...

Psychiatry receives grant establishing Conte Center to study molecular and cellular mood mechanisms

...ed at developing new genetically modified mice and rats that will be used to study molecular mechanisms of...f behavioral tests for depression-like symptoms in rats and mice. Dr. Luis Parada, director of the Center for Developmental Biology and the Kent Waldrep Cen...

The biology of induced memory

...us memories, the hippocampus. "Whether we speak of rats or human beings, we store memories in analogous ar...memories, called the hippocampus. They conditioned rats to fear the environment in which they were (i.e. a small box) by inducing a light electric shock on...

A new approach holds promise for reducing cocaine craving

...aving and relapse in humans. In this animal model, rats are trained to self-administer cocaine injections ...the lever in hopes of getting more cocaine. If the rats are given a single injection of cocaine, they begin the lever-pressing behavior again. Similarly, ex...

Environmental enrichment reverses learning impairments caused by lead poisoning

...ved groups of leadtreated or non-treated (control) rats that were raised in an enriched environment. Enric... and housed multiple animals. Littermates to these rats were raised in standard-sized laboratory cages that the researchers designated as "isolated environm...

Little yellow molecule comes up big

...reductase, human cancer cells and brain cells from rats experienced much more damage and cell death in response to small amounts of hydrogen peroxide, an oxidant, than cells with the enzyme intact. Amazingly, the damage from knocking out the enzyme, and hence bilirubin, was even greater than knocking o...

Beyond patches and pills: the remarkable future of drug delivery

... mimics the spinal cord. They "created" paraplegic rats by placing a defect in their spinal cord that hind...and implanted them in the rats. After a while, the rats with the implants could actually support their own weight. It isn't a total cure, Langer says, but i...

Miniature implantable sensor likely lifesaver for patients

...ue circulation. Preliminary tests using laboratory rats have provided encouraging results. "Although we have more work to do, we are extremely optimistic that this technology will dramatically improve the ability of physicians to care for critically ill patients," Wilson said. While Wilson provides the p...

Moderate alcohol consumption during pregnancy is risky too

...nctional. For this study, three groups of pregnant rats consumed a two-percent, three-percent or five-perc...ut gestation. Three additional groups of pregnant rats were pair-fed zero-percent alcohol liquid diets that were caloric equivalents of the three alcohol d...

Jefferson scientists show neural stem cells can become dopamine-making brain cells in laboratory

...kers showed that mouse neural stem cells placed in rats with Parkinson's disease could develop into brain cells that produced tyrosine hydroxylase (TH), the enzyme needed to make dopamine. Dr. Iacovitti, who also is associate director of the Farber Institute for Neurosciences at Jefferson, wanted to see ...

McLean Hospital and Repligen announce results of brain imaging study of secretin

...en previously reported a finding that treatment of rats with secretin specifically activates the neurons in the amygdala. Repligen is currently developing secretin for autism in a Phase 3 clinical trial program. "These studies show that secretin is active in a part of the human brain involved in social i...

New findings reconfirm toxicity of Pfiesteria cultures

... Pfiesteria with profound learning disabilities in rats and humans....

New studies advance scientific knowledge of drinking water disinfection byproducts

... were absorbed from the drinking water provided to rats and rabbits and whether there were detectable leve... of Toxicology, 20:225-237. Two studies, one using rats and one using rabbits, evaluated pregnant animals exposed to BDCM concentrations of 0, 15(rats), 50 ...

Estrogen may protect against breast cancer

...ne microgram of estradiol per day for three weeks, rats that had not previously borne offspring had no mam...ment of breast cancer. The study was conducted in rats that had never borne babies, to test the duration and level of estradiol needed to induce protection...

Maternal alcohol use during pregnancy may increase offsprings breast cancer risk

...the study. This study involved feeding pregnant rats moderate and high amounts of alcohol during pregnancy. The exposures increased pregnancy estrogen levels, but did not have any adverse effect on normal fetal development. When the female offspring reached adulthood, they were given a carcinogen to ...

The role of obesity and calories in cancer prevention

...n (fish) oil or corn oil, respectively, in nursing rats and their female offspring. Both the low and high fat fish oil diets increased circulating estrogen levels, but only the low fat diet reduced breast cancer risk. Exercise May Maximize Benefits and Minimize Side Effects of Cancer Prevention Regime...

UMBI licenses HIV rat to Harlan

... two genes that make the virus non-infectious. The rats cannot transmit the disease to humans. The HIV tr...y five to nine months of age, the HIV-1 transgenic rats develop clinical signs similar to those of AIDS in humans, including weight loss, skeletal muscle at...

OSU studies breast cancer risk and beef consumption

...ined the impact of zeranol on the breast tissue of rats and on human breast cancer cells, as well," says Lin. "Our research shows that even in very small amounts levels 30 times lower than FDA approved limits, zeranol seems to enhance the effects of estrogen." Still, he says it is too soon to call be...

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(Date:7/21/2014)... kill cancer cells could boost the effectiveness of chemotherapy ... a new study reports. , Scientists at The Institute ... genetically engineered version of the virus used to vaccinate ... alongside isolated limb perfusion chemotherapy given directly to ... an alternative to amputation was more effective in ...
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