Tag: "rats" at biology news

Unnatural light-dark cycles expose duelling circadian clocks

...ies are in synchrony with one another. By exposing rats to a very short day/night schedule a regimen that effectively pushes the limits of the SCN's ability to set the clock to day length researchers have discovered within the SCN two sub-clocks that normally oscillate in unison, but can become disconne...

Animal studies show promise treating severe chronic pain

... Karai et al. performed a series of experiments in rats that showed a single injection into the trigeminal...t to the tail and hind legs. In both experiments, rats maintained their normal motor function as well as their ability to respond to other sensory stimuli,...

Brace therapy for osteoarthrisis, legal issues in TBI research, prosthetic fitting

...aling in rats. One hundred and twenty-four healthy rats received ES and laser treatment to heal an induced wound. While both treatment options were beneficial in all phases of wound healing, ES was more effective than laser treatment in reducing inflammation. Combined with conventional therapies such as d...

NASA-inspired technology may help preserve women's future fertility after cancer treatment

...toward successfully preserving ovarian tissue from rats and mice in culture, including immature egg follic..." In the most recent study using ovarian tissue in rats and mice, University of Pittsburgh scientists focused their efforts on ovarian tissue structures, in...

Prenatal nicotine primes adolescent brain for addiction

...st take up the habit, the team found. The study in rats might provide a biological explanation for the hig...od nicotine concentrations typical of smokers. The rats exposed to nicotine before birth suffered loss of brain cells and a decline in brain activity that p...

How do animals exposed to 24-hour light retain their wake-sleep habits?

...ythm of sleep and wakefulness. Control laboratory rats (N=4) were exposed to artificial continuous light and demonstrated the Aschoff effect, where the circadian activity pattern changes quantitatively with the intensity of the light. This group took on a 26-hour day. This was not the case when the exper...

New research explores 'early bird' and 'night owl' sleep patterns

...olved three different strains of inbred laboratory rats and measurements of their movement and continuous ...p and activity patterns in three inbred strains of rats previously used in sequencing the rat genome. If a difference in the pattern of slow wave sleep and ...

Researchers probe link between nanotechnology and health

...hat nano-sized particles depositing in the nose of rats traveled into the olfactory bulb. At this point the team is not entirely opposed to nanotechnology, Oberdrster explains. In fact, researchers hope to work with the industry, as well as with the American and Canadian governments, to seek solutions if ...

Bim notes in the neuronal executioner's song

...ression in both experimentally induced seizures in rats and in patients with temporal lobe epilepsy. In instances of experimentally-produced prolonged seizures that damaged the hippocampus in rats, Bim expression increased. Blocking upstream activators of Bim or using Bim antisense to block Bim expressio...

JCI table of contents, 2 April 2004

...ression in both experimentally induced seizures in rats and in patients with temporal lobe epilepsy. In instances of experimentally-produced prolonged seizures that damaged the hippocampus in rats, Bim expression increased. Blocking upstream activators of Bim or using Bim antisense to block Bim expressio...

Creating polymers that act like biomolecules

...rporated gene. A preliminary invivo study in rats is now underway in conjunction with the John Stoddard Cancer Center at Iowa Methodist Medical Center in Des Moines. The basic research on polymer synthesis and characterization is funded by the DOE's Office of Basic Energy Sciences. The gene therapy...

UC San Diego bioinformatics experts help reconstruct the genomic makeup of our ancestors

...ourse of evolution for the X chromosome in humans, rats and mice from a common ancestor over 80 million years ago and, for the first time, reconstructs the genomic architecture of mammalian ancestors. "It contributes to the solution of the so-called original synteny problem in biology," said Pevzner, the ...

Scientists compare rat genome with human, mouse

...the crucial areas of biological difference between rats and humans. "This is an era of extraordinary bio...rs ago. Humans have 23 pairs of chromosomes, while rats have 21 and mice have 20. However, the new analysis found chromosomes from all three organisms to be...

Laboratory rat gene sequencing completed

...one-fourth of the human genome is shared with both rats and mice. That's approximately 825 shared, non-repetitive DNA of DNA shared by all three animals. "It's surprising that the amount of shared DNA is so small," Brent said. Relative to their last common ancestor, the rodent lineage has mutated more...

Pre-term labor drug sensitizes brain to pesticide injury

...Center pharmacologists. Their new study found that rats exposed to the pre-term labor drug terbutaline suf...cts on the brain, the team reported. The brains of rats exposed to both chemicals also showed reduced nerve cell activity that the researchers did not obser...

Soy consumption could help prevent prostate cancer and male pattern baldness

...ts demonstrated that injections of equol into male rats reduced the size of the prostate. In one study, the testes of male rats were removed, thereby eliminating all DHT production. When investigators injected DHT into rats, th...

Activity of calcium-handling gene appears to prevent cardiac arrhythmias

...expression of the protein SERCA2a in the hearts of rats reduced the incidence of arrhythmia after heart mu...earts of normal rats. As controls, other groups of rats received gene therapy vectors that induce the production of two other genes, one of which codes for ...

Scientists discover why not enough choline results in fewer brain cells, poorer memory

...s conducted at Duke University, both young and old rats performed significantly better on memory tasks if ...enough choline before birth compared with same-age rats whose mothers were fed choline-deficient diets. The latter showed deficits in the hippocampus and se...

JCI table of contents, 15 March 2004

... CD25 DNA, and show that such vaccination protects rats from adjuvant arthritis (AA), an autoimmune disord...sorders. TITLE: DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response AUTHOR CONTACT: Irum R. Cohen The Wei...

Study suggests possible way to repair damaged nerve cells

...s Alzheimer's and Parkinson's. But new evidence in rats and mice suggests that these neurons could be save...examined brain and spinal cord tissue from healthy rats and mice and compared them to tissue from injured animals. They looked for signs of proNGF and p7...

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