Infections may trigger autoimmunity via rare, but normal process
...ells with the capability of attacking the self are readily identified in healthy individuals, and these cells are typically purged from the system. Autoimmune disorders, such as lupus, arthritis, and diabetes, are understood to result from breakdowns in those protections - they are seen as departures from th...New lab-made stem cells may be key to transplants
...ll as on animal spinal injuries. EBDs reproduce readily and are easily maintained, Gearhart said, and thus... produce tumors. The EBDs bypass all this." EBDs readily divide for up to 70 generations, producing millions of cells without any apparent chromosomal abnorm...Physicians present most comprehensive clinical review of St. John's wort for treating depression
...ottle of St. John's wort, that is. Although this readily available and increasingly popular herbal supplement appears promising in treating depression, many questions remain about its safety and effectiveness, researchers say. That is why physicians at Duke University Medical Center have compiled the most ...Want to get rid of trash quickly? Just add water, study suggests
...ese bins, while the two most readily biodegradable products, yard waste and food waste, comprised less than 5 percent of the total mass. "The disproportionate amount of recyclables (paper and plastic) in the bins were un...Normal salt levels in the lung of the cystic fibrosis mouse
... across the delicate pulmonary epithelium could be readily disturbed by any probes introduced to sample the ASL, raising serious doubts about the accuracy of in vivo measurements. Jayraman and colleagues have now provided a set of tools that may resolve this difficulty. Their approach employs fluorescent...UNC-CH study indicates special vaccines could prevent insulin-dependent diabetes
... for type I diabetes but not in ways that would be readily feasible clinically." A report on the research appears in the Feb. 1 issue of the Journal of Immunology. Besides Tisch, authors are Dr. Bo Wang, postdoctoral fellow; Dr. Donald J. Weaver, now a UNC-CH medical student; visiting scholar Dr. Bo Liu,...JAK-STAT signaling keeps leukemia cells alive
... lymphocytes (CTLs). Unlike normal CTLs, which are readily targeted for destruction by Fas ligand (FasL) binding to the Fas receptor, leukemic LGLs resist Fas-mediated apoptosis. Here, Epling-Burnette and co-workers present data on abnormalities underlying LGL leukemia. Because constitutive activation of STA...Preserving Moroccan forests need not endanger Barbary macaques
...stripped hardly any bark in areas where water was readily available, such as Lake Wiwane, which is one of the few permanent water sources in the study area. Moreover, macaques stripped bark intensely in areas where water was scarce or where the monkeys were excluded from previously available water sourc......t. Smaller molecules like Compstatin are also more readily adaptable to use as an oral medication. Lambris and his colleagues have already demonstrated Compstatins abilities in the laboratory, and the NIGMS grant makes further exploration possible. "Compstatin has great potential as a complement inhibitor...Study of poisonous snakes boosts old Batesian principle of mimicry
...about 6 percent," Pfennig said. "Various predators readily attacked our model scarlet king snakes but only where no coral snakes lived." The UNC team also conducted comparable experiments in Arizona with the same results, Pfennig said. Controls were fake "snakes" bearing either stripes rather than rings...Talking device keeps HIV patients on the straight and narrow
...res of CD4 cells, the immune cells the virus most readily targets, increased by 50 cells/milliliter of blood in patients with the device, but by a fifth of that in those without it. DMAS operates like a "cross between a pager and someone's mother," says Andrade. When it's time for medicine, the device beep...Symposium discusses risks, benefits of plant biotechnology
...Why have American farmers adopted biotech crops so readily and how have Mexican farmers reacted to the technology? What does the public really know - and want to know - about biotechnology? These questions and many more will be discussed Monday, April 2, at a daylong symposium in San Diego during the 221st n...In possible boon to sickle cell victims, basic scientists find reason cells stick
...t boost clogging as the two proteins interact more readily because of the damage. "The next step will be to test our results in a mouse model of sickle cell disease and evaluate potential blockers there," Brittain said. "We are still years away from taking this into the clinic, but we are one step closer ...Global warming: Science, economics, politics
...s a handbook on global climate change that will be readily accessible to policy makers. Gerald North, head of the Department of Atmospheric Sciences at Texas A&M, will speak about the likely effects of the most probable CO2 (carbon dioxide) growth path on temperature, sea level and rainfall patterns, am...Chemistry of life in outer space is topic of two-day symposium, April 4-5
...he Netherlands, has found that amino acids degrade readily when exposed to ultraviolet radiation. This places constraints on the number of amino acids that can survive in some regions of space. (The paper on this research, GEOC 146, will be presented at 2:15 p.m., Wednesday, April 4, in the U.S. Grant hotel,......, they claim that drug-resistant cancer cells more readily take in therapeutic drugs encased in a particular type of molecular envelope. (PMSE 540, Thursday, April 5, 9:20 a.m. Embargoed until 9:15 a.m., April 5.)...Lipoprotein lipase: Location, location, location.
... LpL is active as a homodimer, but the mutant form readily dissociates into inactive monomers, suggesting that HSPGs help maintain the quaternary structure of the protein. The mutant LpL also fails to localize properly: Wild-type LpL remains firmly attached to the lumen of capillaries and releases lipoprote...Breast-fed babies less likely to be overweight children, teens
...tion of breastfeeding may also provide a low-cost, readily available strategy to help prevent childhood and adolescent obesity."......large acquire a distinctive microscopic appearance readily diagnosed by pathologists before they become a cancer. Endometrial cancer is the most common gynecological malignancy, usually developing after menopause, and eventually affecting 2.5 per cent of American women. In evaluating PTEN function, the re......harmacology of aspirin. Moreover, exposure to this readily available drug provides a simple, inexpensive and highly effective means to manipulate the immunostimulatory capacity of dendritic cells," wrote the authors. "While these results are very intriguing, it would be premature to advise patients to inge...