New way to lock DNA-slicing enzyme onto chromosomes could lead to novel anti-cancer drugs
...vision. After the cell divides, each daughter cell receives a copy of the entire set of duplicated chromosomes. "We showed that modifying Top 1 so it became locked onto the DNA molecule is enough to cause cell death," said Mary-Ann Bjornsti, Ph.D., associate member of the St. Jude Molecular Pharmacology depa...... of the respondents The National Cancer Institute receives less than one half of one percent of the federal budget, or $4.6 billion. The vast majority of the nation's taxpayers about 80 percent, according to the survey would rather see that figure increase. We are not doing enough to fund cancer rese...Gene essential for development of normal brain connections resulting from sensory input discovered
...anching of dendrites-the part of a nerve cell that receives input from other neurons. Thus, this branching allows neurons to form many different synapses, or connections, with many other neurons, permitting much cross talk between them. Neurons taken from mice lacking the CREST gene are more linear, like a ...Monkey talk, human speech share left-brain processing
... are being processed in the left hemisphere, which receives greater input from the right ear than from the left. Also, a monkey's ability to perceive such calls is impaired if it lacks the left auditory cortex, but not the right. To find out how this works, the researchers used PET (positron emission tomogra...Green Foundation, Trust gives $12.8 million for UT Southwestern comprehensive research center
...e doing a tremendous job of discovering how a cell receives specific signals and sends information from point A to point B to regulate function," said Dr. Gilman. "But the cell has to listen to perhaps 50 or 60 signals simultaneously to do its job, and we don't yet know the design principles for assembly of s...Fuel-cell microbes' double duty: treat water, make energy
...ead of running down unless it'srecharged, the cell receives a constant supply of fuel from whichelectrons can be released. Typical fuel cells run off ofhydrogen. In a microbial fuel cell, bacteria metabolize theirfood-in this case, organic matter in wastewater-to releaseelectrons that yield a steady electrica...Tony Hunter and Raymond N. DuBois awarded Landon-AACR Prizes for Cancer Research
...rofessional society of their peers. Each recipient receives an unrestricted cash award of $200,000 and presents a scientific lecture at the AACR Annual Meeting, held this year from March 27-31 in Orlando, Florida. This year's winners are: Tony Hunter, Ph.D., professor of molecular and cell biology at The Sa...UVa researchers describe method of protecting chromosomes during cell division
...dying a mitotic system that ensures that each cell receives the right number of chromosomes," said article co-author Todd Stukenberg, assistant professor of biochemistry and molecular genetics at U.Va. To function effectively, a human cell must have one copy of 46 different chromosomes, each containin...Pioneering flu researcher wins major Imperial scientific award
...Ernst Chain Prize is chosen by a panel of five and receives a personal award of UKP10,000 together with a commemorative medal. Sir Ernst Chain was jointly awarded the 1945 Nobel Prize in Physiology or Medicine, with Sir Alexander Fleming and Sir Howard Florey, for the discovery of penicillin and its curative...Study suggests possible way to repair damaged nerve cells
...o do so. p75 is a receptor in healthy neurons, it receives signals from outside the cell, translates them, and feeds them to the cell body. For reasons researchers don't fully understand, neuronal damage causes a dramatic change in p75's behavior. Instead of sending information to the cell body, p75 turn...First large-scale trial of genetically personalised treatment for breast cancer to start soon
...ited about this chance to ensure that each patient receives a treatment tailor-made to manage the particularities of her disease."...UNC's Siderovski wins pharmacology award
...ciences by the Burroughs Wellcome Fund. Siderovski receives the newest award, which carries a $2,500 stipend, April 17 at the society's annual meeting in Washington, D.C.note: contact Siderovski at 843-9363 or david_siderovski@med.unc.edu School of Medicine contact, Les Lang, 919-843-9687 or llang@med.unc.e...'Top Houston Women in Technology' honoree at UH
...th a group of her peers at a gala June 12 when she receives one of the "Top Houston Women in Technology" awards for 2004. This year's awards mark the 25th anniversary of the Association for Women in Computing (AWC), a national organization dedicated to helping women advance and achieve leadershi...Damania of UNC receives Elion cancer research award
... the American Association for Cancer Research. She receives the award today (March 30) at the 2004 AACR Annual Meeting in Orlando, Florida. This marks the second year in a row that the award goes to a UNC researcher. Last year's Elion recipient was Dr. Yi Zhang, as was the 1999 winner, Dr. Yue Xiong. Begun I...Better techniques needed to predict earthquake hazards, UC study finds
...ons are funded by a portion of the compensation UC receives from the U.S. Department of Energy for managing Livermore and Los Alamos national labs. Other UC campuses that helped in the research were Berkeley, Davis, Los Angeles, and Santa Cruz. San Diego State University also participated. The study benefite...Is genetic research hyped by the media?
...mportant to know whether he information the public receives is indeed accurate. In a related commentary, Dr. Celeste Condit points out that journalists and scientists alike may contribute to exaggerated claims in newspapers: the journalist in seeking the "hot" story, and the scientist in pursuing academic pro...ORNL's nanobiosensor technology gives new access to living cells molecular processes
...disease to the organism. "When a cell in our body receives insults such as toxins or inflammation and is damaged, it kills itself. This is nature's way to limit and stop propagation of many diseases such as cancer," said Vo-Dinh. "For the first time we've seen apoptosis occur within a single living cell." A...Leslie Ann Schiff wins 2004 Carski Foundation Award
...d undergraduate majors, for which she consistently receives the highest possible student evaluations. Her commitment to excellence in undergraduate education extends to her own laboratory, where 18 undergraduates in recent years have been able to experience the hands-on approach to science Schiff encourages. ...... blocks a receptor on the surface of the cell that receives excess growth signals, interrupting the out-of-control growth that characterizes cancer. Slamon, director of Clinical/Translational Research at UCLA's Jonsson Cancer Center, said the two studies are important because, as Sledge said, they provide an ...