Tag: "recombinant" at biology news
University of Florida researchers test drug from 'transgenic sheep' in study at Shands at UF teaching hospital
... in thedevelopment of Dolly the cloned sheep, uses recombinant
DNA technology -- inwhich a gene from one organism...e, human plasmaproteins should be produced through recombinant
DNA technology to prevent thetransmission of human blood-borne diseases. The sheep that produce AAT ...
Fred Hutchinson Cancer Research Center researcher one of five awarded $1 million distinguished young scholars grant
...y and a noted expert inprotein crystallography and recombinant
DNA expression biochemistry. Theoverarching aim of his research is to understand how pathogens gain entry tomammalian cell targets during disease processes. Dr. Ghosh's current researchon the mechanisms of host cell invasion by various pathogens pr...
Malaria called failure, puzzle and challenge
...der development, the PAHO magazinenoted. One is a recombinant
protein vaccine developed by SmithKline Biologicalsthat would prevent the malaria parasite in its infectious stage from entering ordeveloping within liver cells of human beings, thus blocking the severe andlife-threatening consequences of malaria in ...
Scientific team identifies gene critical in embryonic development
...functions of genes by deleting them frommice using recombinant
DNA methods. She then monitors the mice closely todetermine the effects of the deletions. The mice are called "knock-out" mice,because specific genes have been knocked out. In this research project,conducted while she was a researcher at the National...
Report in Science on x-ray crystal structure of matrix Metalloproteinase-2 (MMP-2)
...ny hasalso developed methods for the production of recombinant
basal lamina proteinsfor use in wound repair and advanced tissue regeneration protocols....
UCSF Scientists Report On A Transcription Factor That Could Stimulate Heart Cells To Repair Damage Caused By Heart Attacks Or Birth Defects
...op the uncontrolled cell division in cancer. Using recombinant
DNA techniques, Bernstein cloned hCdc5 in 1997 and showed thatit is a novel human protein involved in the division of human cells. Since then,he and his research team have shown that it binds to DNA and acts as atranscription factor -- it regulates g...
Nobel Laureate David Baltimore To Speak To NYU Undergrads
... national policy-making on issues such as AIDS and recombinant
DNAresearch. The Jurow Lecture was endowed by NYU alumnus Irving H. Jurow to bring a leadingintellectual or cultural leader to NYU's undergraduate community. The inaugurallecture was given by Stephen Jay Gould. Last year's lecture was given by Davi...
Researcher Awarded Patent For System To Fight Multiple Diseases
...oli. One purpose of these studies was to developa recombinant
vaccine that would induce anti-streptococcal immun... The technology currently is being used to develop recombinant
vaccinesto prevent or therapeutically treat infections due to Heliobacter pylori, whichcauses ulcers...
Engineered Bacteria Scavenge Heavy Metals
...ts that other processes do not offer: -- Cornell's recombinant
bacteria take over where other processes, such asion-exchange resins or bioabsorbents, leave off by removing heavy metals fromvery dilute solutions and reducing the contamination to the lowest detectablelevel -- less than 10 parts per trillion. -- T...
Researchers Discover Genetic Mutation For Rare Form Of Dwarfism
...have been treating a subset of the population with recombinant
humangrowth hormone. Each patient showed a brisk increase in speed of growth. Levine and his colleagues are continuing their search for the cause ofgigantism. The work was supported in part by the National Institutes of Health andthe...
Oregon Scientists Discover A Second Blood-Brain Barrier; Important Finding For Patients With Brain Cancers And Neurological Disorders
...ivate the dangerous parts of the virus andthen use recombinant
techniques to load genes onto the virus. These recombinantviral vectors can then safely ferry therapeutic genes to their target tissues.)Using iron particles the same size as viruses, the Oregon researchers noticedthat some agents crossed the endothe...
Multicomponent Malaria Vaccine Shows Promise in Laboratory Tests
...1 different P. falciparum proteins to forma single recombinant
protein, which they used to immunize rabbits. Each of the21 segments, or peptides, was selected because it was recognized by the immunesystems of people with malaria, as shown in earlier studies. Furthermore, thepeptides targeted different branches...
UCSF/Gladstone Finding May Explain HIV'S Ability To Infect Cells Lacking The Key Target Of HIV: The CD4 Receptor
.... The answer was yes, determined bysubstituting a recombinant
protein containing solely this extra-cellular portionof CD4 (provided by collaborators at SmithKline Beecham) for the CD4-positivecells. When the CCR5-bearing cell was mixed with the soluble CD4 (sCD4) protein, theresearchers found clear evidence of...
Gene Therapy Incorporates Molecular Rheostat For Controlled, Long-Term Drug Delivery
...ctively with the gene forerythropoietin, or Epo, a recombinant
protein that stimulates red blood cellproduction and is used to treat anemias, and the genes for a transcriptionfactor complex able to regulate Epo. ARIAD investigators had previously shown that this particulartranscription factor could be sw...
Biotech Creates New Solutions And New Problems
DNA techniques were first developed by University ...found shift in the ownership of life forms and the recombinant
DNA toolsneeded to manipulate them. These changes present problems both for growers ofmajor crops, w...
Allelix drug increases bone density and content in women with osteoporosis
...ical trial demonstrating that its compoundALX1-11, recombinant
human parathyroid hormone significantly increases ...s 98 percent. Allelix's ALX1-11 is a proprietary recombinant
version of human PTH and isidentical to the naturally occurring protein produced by the parathyroid ...
Researchers Externally Regulate Gene Implanted In Brain
...s, suggests that gene-transfertechnology using the recombinant
defective virus known as AAV (adeno-associatedvirus) may eventually prove feasible for gene therapy in human brain disorderssuch as Parkinson's disease and epilepsy. A report of the new study appears Dec. 2 in the journal Gene Therapy. The successf...
University Of Chicago Professor Wins $50,000 Bristol-Myers Squibb Award For Distinguished Achievement In Infectious Disease Research
...sion inmaternity wards. With the advent of recombinant
DNA technology in the early 1970s.researchers gained the ability to insert or delete specific genes in manyorganisms and thus learn the gene's function. But the genome of HSV was too bigfor manipulation in the laboratory, so Dr. Roizman's group indu...
Chiron Discovers Significant Hepatitis C Binding Mechanism; Data Indicates CD81 Protein May Be A Virus Receptor
... conducts research and development in thefields of recombinant
technology, gene therapy, vaccines, small moleculediscovery, and genomics....
Reengineered Poliovirus Proves Effective As Vector For Prompting Key Immune
Response In A Study With Mice
...t and destroy pathogen-infested cells. Previously, recombinant
poliovirus vectors had only been demonstrated to i...ived, it may well be possible, he said,to create a recombinant
poliovirus with an antigen that would prompt a CD8T-cell response to cancers that actually affect hu...
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