Tag: "recruits" at biology news
Researchers discover new insight into a common signaling pathway
... called SARA (Smad Anchor for Receptor Activation) recruits
Smad3 to the transmembrane receptor, where Smad3 is converted from an inactive monomeric form into an active trimeric form. Trimeric Smad3 promptly dissociates from SARA and enters the nucleus, where it interacts with cofactors to regulate gene expre...
UCR entomologists report bee-dancing brings more food to honeybee colonies
...nformation in the dance is actually decoded by the recruits
which follow the dances, or whether recruitment is based on the recruits
learning only the odor food source from the dancer, and subsequently searching out the food based on...
Cell division required, twice before fat cells mature
...t cells make and store more fat. But the body also recruits
some primitive fat cells -- preadipocytes to mature, which increases the capacity to store fat in general, explains postdoctoral fellow Tamara Otto, Ph.D. If preadipocytes can't or don't mature, the scientists hypothesize, the body might not be able...
Designer molecules correct RNA splicing defects: New strategy for treating many diseases
...attaches to the pre-mRNA transcript. The other end recruits
enzymes that carry out the actual cutting and pasting. Krainer and Cartegni attached the recruiting portion of the guide protein to a synthetic molecule that can be programmed to bind to any piece of RNA according to its sequence. The researchers de...
Puzzle solved on how influenza builds its infectious seeds
... in the infection process. This signal selectively recruits
the necessary set of eight viral RNA strands to make a complete influenza genome within the infectious particles for the influenza A strain, the most virulent and potentially dangerous flu virus. "What's unique about this virus is that its genome is ...
Researcher explores tumors' survival strategy
...umen through which blood will eventually flow, and recruits
supporting cell types and matrix components to form a new, functional vascular bed that is believed to accelerate wound healing. The fact that many tumors also activate angiogenesis to survive has helped make it a hot topic in science. Dr. Motamed, w...
Rb2 gene may play role in determining effectiveness of drug therapies against breat cancer
...s, pRb2/p130's signal is damaged or mutated and it recruits
a different sequence of molecules which cause Rb2 ...cells. By understanding this mechanism of how Rb2 recruits
molecules, he says, researchers will be able to eventually design drugs that are very precise in the...
Chlamydia infection prevalent among female army recruits
Nearly 10 percent of female Army recruits
tested positive for the bacteria that causes the s...my. The researchers also found that the number of recruits
testing positive for chlamydia increased over the four-year duration of the study, from 1996 to 1999...
White House awards National Medal of Science to Rockefeller University's James Darnell
... laboratory at the university. Ten of the first 12 recruits
in the program became full professors at Rockefeller, and more than 20 such young scientists have become tenured Rockefeller University professors through this effort. Darnell received the Howard Taylor Ricketts Award of the University of Chicago Med...
Herpes research uncovers possible clue to Alzheimer's disease
...teracting with APP, a putative motor receptor that recruits
a microtubular motor, kinesin, for transport through neurons. This was the first time scientists had observed any physical interaction between the herpes virus and APP. Without the APP, the virus moves backward up an axon (a long extension of a neur...
Study suggests new view of gene activation as a dynamic process
...val of the ubiquitin group, in this case, actively recruits
crucial molecules into the gene-activation process and then releases them at specific times and locations within the gene. "The histones and the intricate pattern and sequence of modifications that plays upon them are fundamental to this process," B...
Hopkins scientists overcome main obstacle to making tons of short, drug-like proteins
...me "reads" three-bit sections of messenger RNA and recruits
a complementary three-bit-containing piece of transfer RNA, which is attached to its corresponding amino acid. The ribosome's machinery then chops off the amino acid and adds it to the growing peptide string. To harness this natural process to do the...
Protein key to trafficking in nerve terminals
...esicle off the cell membrane. Others think that it recruits
other proteins to help pinching off the vesicle. When Dap160, which binds dynamin, is removed from the vesicle retrieval process, the pinching-off either does not occur properly, or occurs too late. As a result, the vesicle keeps growing and sub...
Study reveals surprising 'remodeling' property of gene regulation process
... that when a gene needs to be turned off, the cell recruits
the nucleosomes back to a particular location in the genome, thus helping to ensure that expression of the gene is stopped. Nucleosomes are complexes of proteins that were thought to simply bind to genomic DNA and condense it into structures called c...
Researchers identify protein promoting vascular tumor growth
...State University Medical Center. When MCP-1 recruits
macrophages to the tumor site, it stimulates new blood vessel development, or angiogenesis, in endothelial cells that make up the lining of blood vessels. That proliferation can cause the tumors to grow because new vessels develop and allow blood to ...