NIH awards $18.2m to The Burnham Institute to develop Center on Proteolytic Pathways
... Director Elias A. Zerhouni, M.D. "As the centers refine the technologies, these valuable resources will be made available to hundreds of investigators across the country who are working in every disease area."...Gene clusters predict atherosclerosis severity, susceptibility
...critical study in demonstrating that we can indeed refine genomic techniques to address the risk for complex... animal mouse models of atherosclerosis to further refine their techniques. Since it is not practical to test samples of aortas in living patients, the also r...Hardy buoys: Texas A&M project predicts oil spill movements
...rsity researchers has developed - and continues to refine - a system of buoys in the Gulf of Mexico that can accurately predict the movement of oil spills. Such spills can present Texas-sized problems, both environmentally and economically, to the state's coastline. The buoys can even be used to locate shi...Peering inside the body, with a new spinliterally
... organs or parts of tissues. Wind will continue to refine the technology, for which he recentlyreceived two patents, and PNNL will make it available for licensing. Asa precursor to studies in humans, Wind said, safety trails in animalswould be necessary to see how strong a field and fast a spin they couldst...Protein vaccine fully protects mice from lethal aerosol challenge with ricin toxin
...uman primates. He said the team also is working to refine a scaled-up production method that is robust and reproducible. This involves optimizing the fermentation process, developing a process for purification, and refining the analytical methods for characterizing both the manufacturing process and the fin...U of T research answers key question in biochemistry
...es for small, fairly simple proteins. They hope to refine their methods and apply them to other systems with intermediate states. If scientists can understand the pathway a protein takes from one state to another, they may be able to predict protein structure, something that can't be done very reliably......mechanics and control mechanisms, we can help them refine their movements and avoid injury to the body," McNitt-Gray said. "This goes for dental technicians, athletes, children who play sports and people who are trying to recover from crippling injuries, such as damage to the spinal cord or losing a limb."...Calcium supplements associated with decreased risk of large bowel polyps
...trient interactions with calcium will help further refine optimum cancer protective strategies and may clarify the mechanisms by which calcium has its effects in the large bowel," the authors write. In an editorial, Arthur Schatzkin, M.D., Dr.P.H., and Ulrike Peters, Ph.D., of the National Cancer Institute...First ever standards linking climate change, biodiversity and poverty seek global peer review
...elangi, and SC Johnson. Other institutions helping refine the standards and ensure broad input include the World Agroforestry Center (formerly ICRAF) in Kenya, the Centro Agronomico Tropical de Investigacion y Ensanansa (CATIE) based in Costa Rica, and the Center for International Forestry Research based in...BioCDS could hit No. 1 on doctors' charts
...eveloped, significant work will need to be done to refine these techniques sufficiently," he said. "It will be at least 10 years before doctors have Bio-CDs at their disposal, and that assumes everything goes smoothly in the interim."...Scientists identify six genes associated with survival in diffuse large B cell lymphoma
...use they propose that molecular profiling may help refine prognoses in this difficult-to-treat blood cancer," said Ronald Levy, MD, Professor of Medicine and lead author, Stanford University Medical Center. "Currently, physicians rely on the International Prognostic Index (IPI) to evaluate patients with DLB...Biosensor-regulated gene therapy reduces heart attack damage in mice
...uture attacks. While much work remains to test and refine such a therapy, Dr. Phillips said, this new concept might eventually be an alternative to stents and bypass surgery. People who suffer one heart attack are at higher risk for subsequent attacks. Often lack of blood flow to the heart muscle, known as ...Faster carbon turnover in basal food-chain levels in aquatic than terrestrial ecosystems
...s of higher CO 2 availability. These results help refine current and future estimates of global carbon cycling and implications on climate change....Double mastectomies significantly lower risk of breast cancer in women who are genetically at risk
...t cancer. "The goal of future research is to refine these estimates for women in specific situations: according to the type of BRCA mutation; type of mastectomy different procedures remove varying amounts of breast tissue; and the age and timing of surgery many women past their child-bearing years a...UC San Diego faculty receive funding from von Liebig Center to commercialize academic research
...thetic Bone" $50,000 The aim of this project is to refine a new method for creating synthetic bone for biomedical applications such as dental implants and biocompatible prosthetic interfaces. Vecchio recently developed a new method to convert marine skeletal structures into new materials with a composition ...Out-of-balance ecosystems play role in demise of amphibian populations
...appear as a book chapter this year -- dramatically refine the data on parasitic activity and argue that physically and chemically induced changes of aquatic habitats are taking a toll. "We have to be asking what human activities are contributing to imbalances in these ecosystems to set the stage for more se...'Elves' makes protein crystallography easier
...rsion, build a model, and just process the data or refine the model. No human intervention is needed as Elves tries different parameters. "Computers are faster today and people are automating many steps in the process of analyzing X-ray diffraction data, and Elves combines all these techniques together,"...Bacteriophage genomics approach to antimicrobial drug discovery published in Nature Biotechnology
...raries and applying medicinal chemistry to further refine and evaluate those inhibitors. PhageTech has also continued to expand its phage genomics platform from Staphylococcus aureus to other bacterial pathogens including Streptococcus pneumoniae and Pseudomonas aeruginosa....Abandoned penguin colonies may help refine Antarctic climate studies
...old. Those techniques, they say, can also help to refine our understanding of climatic change on the southe...scales. "The evidence from these colonies can help refine those other records," said Emslie. "They are adding a higher resolution to the climatic record in An......eup of the two species, C. elegans researchers can refine their knowledge of this tiny human stand-in, fill in gaps about gene identity and function, as well as illuminate those functional elements that are harder to find, and study the nature and path of genome evolution....