Neurogenetics Lab Scan Suggests Genetic Linkage On Chromosomes 4 And 11
...me 81, Number 3) highly suggestive evidence in one region of chromosome 11 and good evidence in one region of chromosome 4 for linkage to alcohol dependence (commonly termed alcoholism) risk. Consistent with...COGA Genome Scan Suggests Linkage On Chromosomes 1,2,4, And 7
...ng pair groups, strongly suggesting a gene in this region that is important in alcoholism susceptibility," s...sibling pairs suggests a protective locus near the region that contains the alcohol dehydrogenase ( ADH ) gene cluster. ADH2 and ADH3 in that cluster are know...Scientists Discover Proteins Which Help Set The Body's Clock
... CRY 1 and 2, which respond to the blue-white region of the sunlightspectrum, are only the second set of light-reactive proteins found in humans inmore than 120 years. The other protein, rhodopsin, which is found in the rodsand cones of the eye and controls vision, was discovered in 1877....40% Of Developing World Infants Stunted
...he period. Of the 25 countries in the sub-Saharan region with data available, however, 13 made substantial progress, but in 12 countries, the rate of stunting got worse. "We now understand that the prevalence of stunting remains high in part because it takes more than one generation for growth potential ...USGS Responds to Amphibian Declines With Program In Great Smokey Mountains National Park
...ears in the Great Smoky Mountains National Park, a region that has the greatest diversity of amphibians in North America. The USGS survey is in response to the worldwide reports of sharp declines in the numbers of amphibians; researchers believe that by monitoring the status and trends of amphibians in...Mouse Model Of Down Syndrome Offers Glimpse Into Role Of Specific Genes In TheDisorder
...segment of mousechromosome 16, the equivalent of a region on chromosome 21 in humans that isassociated with ...represent just a particularly small portion of the region ofchromosome 16 that has strong parallels to some of the neurological disorders ofthe disease in hum...Rockefeller University Researchers Continue Search For Genetic Ties To Hearing Loss
...ical distribution of these loci, refine thegenetic region for known NSHL loci, and isolate NSHL genes. Since its inception in February 1997, the study has grown to encompass 73families from the U.S., representing about 1,000 individuals. Families fromEurope and the Middle East are also participating in the......udden, it wasoften fatal, and it was confined to a region where military research takesplace. To some, it lo...ease,"Zelicoff says. Also, both New Mexico and the region surrounding Chelyabinsk-70have unusually high incidences of hepatitis C. Info gathering began Monda......ntification process was to localize thechromosomal region where the gene responsible for the genetic disorder islocated. This process was conducted at Boys Town National Research Hospitalunder the direction of William Kimberling, Ph.D., director of genetic studies,with the help of research associates Michae......s, the company that is developing theprotein. "The region of the brain that's damaged dies, but the protein rewiresthe circuitry around the damage, through tissue surviving the stroke," he says. The experiment, reported in NeuroReport (vol 9, p 1441), used rats inwhich the researchers had induced s......in by activating silent synapses, however. A brain region called therostroventral medulla (RVM) sends a chemical signal to cells in the dorsal hornof the spinal cord, they discovered. The neurotransmitter serotonin activatessilent synapses in dorsal horn neurons. Inefficient, or silent synapses wer...Scientists Develop New Computer Program To Speed Determination Of Gene Function
...ubiquitous simple sequences) to a 750,000 basepair region on human chromosome 3P. Minna used this section of DNA to studysmall-cell lung carcinoma, one of the deadliest forms of cancer. "We ran the code on this region, identified about 40 markers and testedthem," said Garner, co-director of the Bio...China And USGS--Working Together On Environmental Issues
...yzing samples of coal obtained from this high-risk region and comparing themto coal samples from the low-risk region of Geiju, China, to determine whichcharacteristics of the coal, if any, are associated with increase......olved all families. But the association betweenthe region on chromosome 4 was stronger for families that have both CD and UC,especially for those of Ashkenazi Jewish heritage. "Although we now have some great clues, we are years away from isolating theindividual genes that contribute to this disease," said ...A Synthetic Peptide Destroys Brain Plaque Implicated in Alzheimer's Disease
...custom-designing a rogue peptide that mimicked the region of the amyloidprotein that regulates folding but contained certain amino acids unable to adoptthe pleated form. They call the rogue a "beta-sheet breaker." "We believe that in order for amyloid to be formed, the protein has toadopt this beta-she...Alstrom Syndrome Genetics Studied At Jackson Laboratory
...fy the gene'slocation by looking for a chromosomal region that was identical among all five,and always present in two copies. Testing performed by Senior Research Assistant Gayle Collin, a FrenchAcadian herself, on DNA samples from the interrelated children resulted in 1996in the successful mapping ...Cultured Neural Stem Cells Reduce Symptoms In Model Of Parkinsons Disease
...s of rats that were missing the dopamine-producing region on one side oftheir brains, the rats' Parkinsonian symptoms gradually diminished. Most showedabout a 75 percent improvement in motor function 80 days after they received thetransplants. At present, the cells can be multiplied only 10 to 100 ...USGS Measures Coral Reef Recovery In Culebra, Puerto Rico
...he Caribbean have shown that corals throughout the region are being stressed.Nevertheless, the reefs in Culebra are in very good condition as compared toreefs in other parts of Puerto Rico, Florida, and the U.S. Virgin Islands. As the nation's largest water, earth and biological science and civilian mappin......rmal patterningof neural tissue growth in the back region of the embryo and other tissue typesin the abdominal region. "In the swirl mutant, all abdominal tissue is absent, but the surprisecame when we started to look at the dorsal neural tissue and found that most ofit expanded and took over the ...New Long-Term Ecological Research Site Funded For Plum Island Sound Ecosystems Study
...uch as long-term sea level rise. In thiscase, the region is the U.S. East Coast." Scientists working on the projectalso hope to discover how the biota of different biogeographic provinces areaffected by similar nutrient inputs, freshwater supply, and availability oforganic matter. "Despite an awar...