New Gene Therapy Technique Results In 60 Percent Tumor Regression Rate
...ncer cells in animals, achieving a 60percent tumor regression rate without the potential dangers associated with...we had such positive results of total andpermanent regression of the tumors we studied," Wagner says. "While most cancercells are dividing, oncologists tell us th...Rapid Progress Reported On New Class Of Anti-Cancer Drugs
...en amazingly successful," he said. "Completetumor regression is observed, with no sign of toxicity in many animal models."Also, Casey said, in vitro studies had revealed that FTase inhibitors worked ona far broader range of human cancer cells -- about 40 percent of those tested --than was expected. Such broad ...Dietary Determinants Of Iron Stores In A Free-Living Elderly Population: The Framingham Heart Study
...d various dietary factors was assessed by multiple regression analysis. Subjects whose ferritin concentrations might be pathologically elevated because of infection, inflammation, liver disease, or genetic hemochromatosis were excluded from the analysis. After we controlled for sex, age, body mass index, total ...Atlantic Salmon Cancer Virus Identified
..., but ratherseem to disappear spontaneously. Such regression of tumors is of interest toCasey, Bowser and other cancer researchers because an explanation for thephenomenon could lead to better treatment or prevention of human cancers. SSSV is classified as a retrovirus, Casey says, because it contains hall...Scientists Study Protein's Role In Tumor Development In Fish
...tudies of the role cyclin plays in tumor onset and regression isa relatively new focus for Holzschu and his collaborators at Cornell University.Lorie LaPierre, a former doctoral student at Cornell who now is a postdoctoralresearcher in biomedical sciences at Ohio University, was studying walleyeretroviruses whe...Scientists uncover how a colon-cancer prevention drug works
...al Chemistry. Sulindac has been shown to cause the regression of benign colon polyps, therebyhelping to prevent development of colon cancer. The drug inhibits the growth oflaboratory-grown cancer cells that do not express cyclooxygenase, whichsynthesizes inflammatory mediators known as prostaglandins. Gaynor an...Novel anti-cancer agent shows minimal side effects with preliminary evidence of tumor shrinkage
... patients with renal cell cancer experienced tumor regression after other treatments had failed. At the doses used so far, the main adverse effects were mild skin reactions and inflammation of the mucous membranes, which occurred at all dose levels studied, but did not increase in intensity with higher doses o...Introgen Therapeutics reports progress in gene therapy studies at annual ASCO meeting
...ed local tumor control defined as greater than 50% regression of their total disease, and had a negative biopsy ... or 9 of 17 patients, experienced greater than 50% regression of their primary tumor, and had a biopsy at the conclusion of treatment which confirmed no active ca......were also observed: one patient exhibited complete regression of an abdominal mass as evidenced by a CT scan and a concomitant normalization of the CA-125 level, a protein found in the blood, which is useful for detecting and evaluating ovarian cancer. In 3 other patients, there was a transient (1-3 months dur...New robotic microarray technology finds novel genes involved in cardiac hypertrophy and recovery
... the identification of genes expressed only in the regression phase. "Hypertrophy has been studied to death," Br...ant to investigate is possible leads for modifying regression therapeutically."...UNC opens first clinical trial of vaccine treatment for advanced breast cancer
...or long as you want." "We're looking for clinical regression of established tumors. By definition, this means at least a 25 percent shrinkage of established tumors," Dr. Serody said. Serody acknowledges that the engineered protein may prove no more effective than treatment with the standard protein. This is t......provement was at times impressive. Unfortunately, regression usually occurred, often to the pre-treatment status. "Additional research should address whether there are better drugs for this treatment, how long therapy should be continued, and what can be done to prevent relapse once treatment is stopp...Hopkins researchers develop method to predict response to chemotherapy
...cantly better responses to chemotherapy, including regression of the tumor and increased long-term survival. This is compared with one patient of 28 with unaltered MGMT genes who responded to the chemotherapy. Patients with altered MGMT genes lived an average of 13 months longer than the other patients. Th...Long-term data on Dendreons Mylovenge vaccine presented at American Society of Hematology
...d with amyloidosis, indicate that Mylovenge causes regression or stabilization in more than 30 percent of patien...with Mylovenge. Seven had disease stabilization or regression lasting in four cases for 18 months or longer. "Responses such as these are impressive especially......da, fetal vitamin A deficiency syndrome and caudal regression syndrome....Betting on climate change: Alaskan gambling contest yields treasure trove of scientific data
...e," he adds. Sagarin says he might use his linear regression analysis to predict when the breakup will occur next spring. His advice for those contemplating purchasing a ticket for the 2002 Ice Classic: "I wouldn`t enter a date that`s too late in the year."...Highly specific biological agents attack mechanisms of treatment resistance
...a complete response rate of 25%-30% and mean tumor regression of more than 90%, compared with 4% complete response and mean tumor regression of approximately 30% with paclitaxel alone. A weekly schedule of 50 mg/kg of 17-AAG on three consecu...Influence of gender on upper airway structure and function during obstructive sleep apnea
... resistance at peak airflow (Rpk). Multiple linear regression was utilized to determine whether gender, age, BMI...lues to the natural logarithm. Multiple logistic regression analysis was used to determine whether gender, age, BMI, NC, or RL predicted whether a subject had &...The body's production of melatonin may be the reason why the elderly can't get a good night's sleep
...h the older and young groups of subjects. A linear regression fitted to both data sets indicates that the nature of this relationship is different between the two groups, with an earlier wake time associated with an even earlier circadian phase in the older subjects. Other key findings included: A comparison ...