St. Jude researchers decipher structure, activity of enzyme key to biochemical pathways of life
...he cell uses E1 activating enzymes to keep a tight rein on all of the various biochemical pathways it must activate," Schulman said. "Otherwise the cell would be chaotic and wouldn't be able to perform the tasks it is supposed to do in the body." Each type of E1 activating enzyme coordinates a specific f...UV Radiation Induces Vitamin A Deficiency In Skin
...d by UV radiation, the destructivepathway has free rein to inflict a great deal of damage," Voorhees said. Understanding how these two biochemical pathways work in human skin may lead tonew medications or treatments that could block the harmful effects of UVradiation. "Our findings suggest that applying ......enes known as tumor suppressors, whosejob it is to rein in cell growth. The work, by AssociateProfessor John Ludlow, graduate student Deidre Nelson, and post-doctoral researcher Nancy Krucher, appears in the Feb. 14 issueof the Journal of Biological Chemistry . Cancer is a tale of cells growing out ...