Anti-interferon beta antibodies in MS care: A consensus
...tas, which reduce the frequency and severity of MS relapses or attacks, reduce brain lesion development and generally delay future disability. Few options for treating MS existed until these biologic therapies became available. However, some MS patients taking an interferon beta (Avonex, Betaseron or Rebif)...New ovarian cancer hope for women
...anced stage. Even after surgery and chemotherapy, relapses are common." According to the American Cancer Society, the survival statistics are dismal. Three out of four cases of ovarian cancer are diagnosed in late stages. Last year alone, nearly 14,000 women died of the disease. The best currently availabl...Clinical study results published in NEJM show promising data on Antegren (natalizumab)
...izumab) reduced new inflammatory brain lesions and relapses in patients with relapsing forms of multiple sclerosis (MS). The use of natalizumab in the treatment of MS is currently being investigated in Phase III clinical trials. An investigational study was also published in today's NEJM that showed promisi...Antegren (natalizumab) clinical study results published in New England Journal of Medicine
...ducing new inflammatory brain lesions and clinical relapses in patients with relapsing forms of MS were also published in this week's issue of The New England Journal of Medicine. "The data published in these studies are very important in our understanding of immune-mediated diseases like Crohn's and MS. B...Researchers distinguish new type of leukemia
...mosome 11, called a translocation, suffered severe relapses after chemotherapy. Researchers had discovered that the translocation involved a gene that they called the mixed lineage leukemia gene, or MLL . Korsmeyer, Golub and their colleagues theorized that the MLL translocation might cause aberrations in me...Stanford, UCSF researchers home in on key gene in multiple sclerosis progression
... the evolution of the disease, determining whether relapses and remissions develop. "With this finding, a major piece of the puzzle is in place," said Oksenberg, "but there is much more work to be done." Steinman added that in addition to osteopontin, a number of other genes found warrant further exami...Fighting breast cancer at the molecular level
...s to therapy. The tests could also detect patient relapses much earlier. The diagnostic tests the researchers are trying to develop include blood and bone-marrow tests, as well as tests on tissue from lymph-node biopsies. The project is under the supervision of Gus Kousoulas, Ph.D., director of the M...Searching for new medications to treat alcoholism
...ly available medications that help prevent alcohol relapses in alcoholics." "It is also clear that compliance with taking naltrexone is a crucial aspect of its efficacy," added Anton. "One of the benefits of 6 beta-naltrexol as an alternative to the parent compound naltrexone is that it is longer acting (h...MS clinical trials confirm approach, demonstrate need to carefully refine targeted peptide therapy
...nificant difference in the frequency or number of relapses in patients receiving the therapy vs. the placebo, although the volume of new inflammatory brain lesions was reduced in some patients who received the 5-mg dose of the therapy. However, 9 percent of the patients enrolled in the study developed syste...Breast cancer relapse rates appear higher in women who have cancer-causing gene, Yale study finds
...BRCA1 or BRCA2 gene may be at higher risk for late relapses than theircounterparts who do not harbor these mutations. "Previous studies have established that women with BRCA1 or BRCA2 genes have avery high rate of developing breast cancer," said Bruce G. Haffty, M.D.,associate professor of therapeutic radiol...Continued Prophylactic Treatment Of P. Marneffei Can Prevent Relapse
...lapse is highly preferable to treatment since some relapses can notbe treated successfully. Dr. Nelson said, "This regimen should be the standardof care for patients with AIDS and P. Marneffei infection which is very commonin AIDS patients in Thailand." The study was supported by grants from Janssen ......n multiple sclerosis. "We have been able toprevent relapses in the mouse version of multiple sclerosis usingan...heUnited States. Many with the disease suffer from relapses after the initialonset of such symptoms as numbness and paralysis. Trying to remedy theserelapses is...