Fat cells could provide the key to a longer life
...cted diets are far less likely to get diabetes and related disorders, this suggests that genes involved in glucose metabolism might be linked to the genes involved in ageing." Previous studies have shown reducing DAF-2 function during development affects only fertility, but in adulthood reducing function aff...Damaged genes in aging human brain provide clues to cognitive decline
...ents may be occurring in the aging brain, possibly related to gene damage. The researchers then went on to show that many of the genes with altered expression in the brain were badly damaged and could not function properly. They showed that these genes also could be selectively damaged in brain cell...Utah scientist helps discover new mouse species -- and maybe a new genus
... the other co-leader of the team, said it was "not related to any of the other rodents" found in the northern...mon." Rickart and Heaney said the animal is not related to any of the other rodents known on the main Philippines island of Luzon and they are not clear yet...Parting genomes: UA biologists discover seeds of speciation
... cacti in western deserts. Whether the two closely related fruitfly populations, designated Drosophila mojave... inability of fruitflies to hybridize with closely related species, but in all cases those genes were discovered long after the two species diverged. Those gen...Common worm provides insights into salmonella virulence
...nella infections. The researchers found four genes related to the Salmonella's "molecular syringe" that are r...s hosts, Aballay explained. "In this study we have related several genes located in pathogenicity islands to S. enterica pathogenesis in worms," Aballay said. ...Choice of food helps hungry caterpillar
... Thinking the absence of elicitor was related to the caterpillar's food, the researchers fed H. subflexa on a different food source and fed a different caterpillar on Physalis angulata. The Physalis-fed caterpillar did not produce the elicitor either, but H. subflexa, fed on a different food, d...Susceptibility of mice to mousepox offers promise of smallpox protection
...ction for humans against the threat of smallpox, a related virus, as a weapon of bioterrorism. HHMI international research scholar Gunasegaran Karupiah, a scientist at the John Curtin School of Medical Research at the Australian National University, and colleagues have identified proteins that determine whic...Obesity and hypertension: Two epidemics or one?
...th an increased BP. The increase in BP is closely related to the magnitude of weight gain, and even moderate weight gain is associated with an increased risk of developing hypertension. However, there is considerable inter-individual variability in the BP response to weight gain and not all obese individual...CSIRO research in greatest biotech show on earth
...peed drugs to their targets Gene Silencing and related techniques powerful new gene technologies to enhance therapies and control plant and animal breeding Diagnostics new approaches to infectious disease identification Biomaterials and Tissue Engineering novel materials for cartilage repair, ...U. Iowa muscular dystrophy discovery may lead to new treatment approaches
...protein expression in cells from patients with the related muscular dystrophies, Fukuyama Congenital Muscular Dystrophy, Walker-Warburg Syndrome and Muscle-Eye-Brain disease, restored the normal functions of alpha-dystroglycan without adversely affecting the cells. Even though each of these distinct muscula...When combining new oral anti-cancer agents with standard chemotherapy, timing may be crucial
...cularly targeted agents, not just erlotinib. In a related presentation at the ASCO meeting, Gumerlock reported that in laboratory testing of tumors in mice, a selective proteasome inhibitor, PS-341, significantly inhibited non-small cell lung cancer growth when administered sequentially with docetaxel. But ...Avastin-Tarceva combo provides 'one-two' punch against lung cancer
...has suggested that activities of EGFr and VEGF are related EGFr appears to play a role in angiogenesis, while blocking VEGF appears to interrupt EGFr signaling. As a result, the researchers suspect that a dual blockade of these targets may be synergistic.Interim results from this research were presented at ...Gene expression ratio identifies risk of recurrence in breast cancer patients receiving tamoxifen
...released online today (www.cancercell.org) because related material is being presented at the June 5-8 American Society for Clinical Oncology meeting. The study was supported by grants from the Avon Foundation, the U.S. Department of Defense, and the National Cancer Institute. Tamoxifen, which blocks the in...Researchers report major advance in gene therapy technique
...one artery feeds a whole limb," notes Wolff. In a related procedure, they experienced excellent results with high-pressure injection of genes into the tail veins of rodents, a technique that yielded extensive gene expression in the animals' livers. "We think the genes traveled from the capillaries through...Albany high school student adds to understanding of breast cancer gene
...chool to learn all I could about how this gene was related to breast cancer." Figge learned that normally, the BRCA-1 protein acts to suppress breast and ovarian tumors in women. But when the genetic code for BRCA-1 is errantly altered, the gene may lose its ability to suppress tumors. ...$5.5 million awarded to tree-ring research and climate studies
...ts of the Asian monsoon system, and its impacts on related environments," said Ed Cook, Doherty Senior Scholar, Lamont-Doherty Earth Observatory, and Principle Investigator for this study. Analysis of tree ring data throughout 'Monsoon Asia' will enable scientists to reconstruct and analyze regional climate ...RNAi delivery system crosses blood-brain barrier to target brain cancer
...R is set into action when it binds a growth factor related to epidermal growth factor, a hormone growth factor that travels outside of cells in the blood. Activated EGFR normally induces a flow of calcium across tumor cell membranes. That calcium mobilization was minimized in the brain cancer cells treated w...Umbilical cord blood transplants, bone marrow transplants save lives
...nly for a Hospice program (because no matches with related or unrelated living donors could be found) to go back to work or school full-time. "Without the cord blood transplantation, they would not have survived," said Stiff....Clue found on breast tumors distinguishes patients with better survival odds
...ated whether the tumor levels of active Stat5 were related to how well the patients did over the next 5-10 years after initial treatment. After analysis of over 1,000 patients' tumor samples, the team found that loss of Stat5 activity correlated with higher risk of death. This increased risk was especially ......e Utah Museum of Natural History, said it was "not related to any of the other rodents" found in the northern..." Heaney and Rickart said the animal is not related to any of the other rodents known on the main Philippines island of Luzon and they are not clear yet...