Tag: "renal" at biology news
JCI table of contents September 15, 2004
....pdf A Niche for Kidney Stem Cells TITLE: The renal
papilla is a niche for adult kidney stem cells AUTHOR CONTACT: Juan A. Oliver Columbia University, 630 West 168th St, New York, NY 10032, USA Phone: 212-305-6938; Fax: 212-305-3475; E-mail: email@example.com View the PDF of this article at: https:...
Other highlights in the September 1 JNCI
...used to treat patients with metastatic melanoma or renal
cell carcinoma, but efforts to improve the treatment's efficacy are hampered by the lack of knowledge of its molecular targets. In a new study, William E. Carson III, M.D., of the Ohio State University in Columbus, and colleagues describe the use of ...
JCI table of contents, 16 August, 2004
...ved ET-1 in regulating systemic blood pressure and renal
Na excretion. TITLE: Collecting ductspecific knockout of endothelin-1 causes hypertension and sodium retention AUTHOR CONTACT: Donald E. Kohan University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA Phone: (801) 581-6709; Fax: (...
Iron can have negative side effects on people with kidney disease
... effective therapies to help people with end-stage renal
disease (ESRD), which occurs when kidney disease h... patients, iron therapy may exacerbate progressive renal
damage. Yet iron therapy remains essential in the treatment of patients with chronic kidney disease....
FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
...ated with cyclosporine and in patients with severe renal
insufficiency. VYTORIN to be available in various doses VYTORIN has been approved for use in patients at the following doses: 10/10 mg, 10/20 mg, 10/40 mg and 10/80 mg. Across the dosing range, the ezetimibe component of VYTORIN is held consta...
Drug prevents chemotherapy-induced hearing loss, study finds
...cts of cisplatin use, such as gastrointestinal and renal
toxicity. In fact, rats given NAC 15 minutes before chemotherapy exhibited less overall toxicity, shown as weight loss, seven days after treatment. "They all lose weight, but it's significantly less" following NAC treatment, Dickey said. Researchers ...
Was Atkins right?
...rements did not produce any adverse effects on the renal
and hepatic functions, on oxidative stress or on the calcium balance. On the contrary, exchanging carbohydrates for proteins was beneficial regarding body composition, basal triglycerides, glucose, leptin, and insulin plasma concentrations. The resul...
Newly grown kidneys can sustain life in rats
...aron Rogers, research instructor in medicine, gave renal
primordia transplants to 5- and 6-week-old rats. P...the newly grown kidneys can perform many essential renal
functions. "For example, we've shown that they can excrete inulin, an inert sugar that we inject int...
Lupus Research Institute awards $3 million in novel research grants to further new science in lupus
...cance of either of two different patterns of lupus renal
glomerular injury and inflammation recently identified in work by Dr. Karin Peterson and colleagues. One patient subset had a milder form of proliferative nephritis with interferon-induced genes suggesting the entrance of activated NK cells. A cont...
A protein's role in progressive renal disease
...ough it's not clear what causes FSGS, this form of renal
pathology is becoming more common. By using the g...ach to figure out how the defective protein wreaks renal
havoc and how these physiological changes lead to FSGS. Using biochemical analysis, cell-based stud...
Sex-specific differences in gene expression related to drug metabolism and hypertension
...cific propensities (e.g. anemia, hypertension, and renal
dysfunction)." Significant differences in gene expression were observed in the mouse liver, kidney, and reproductive tissues. Many of the differentially expressed genes were involved in drug and steroid metabolism and regulation of fluid balan...
Obesity and hypertension: Two epidemics or one?
...a role. Two of the most common causes of chronic renal
(kidney) failure, diabetes and hypertension, are c...t gain and the accompanying cardiac, vascular, and renal
dysfunction. This comprehensive review reveals that there is much we do know about the association ...
JCI table of contents, 1 June 2004
...It -- the Kidney's Differentiated TITLE: Distal renal
tubular acidosis in mice that lack the forkhead transcription factor Foxi1 AUTHOR CONTACT: Sven Enerback Goteborg University Goteborg, Sweden Phone: 46-31-773-3334; Fax: 46-31-416-108 E-mail: firstname.lastname@example.org View the PDF of this article ...
Inflammation, hypertension are focus of major new MCG research program
...istry core leader on the grant. Dr. John D. Imig, renal
vascular biologist, and Dr. Edward W. Inscho, physiologist, who are both project leaders, are looking at signaling mechanisms that effect kidney response. "We think the elevation of cytokines that occurs in cardiovascular disease is actually decreasi...
APS announces four 2004 Young Investigators awards
...outstanding promise in the field of epithelial and renal
physiology and will be given on Dr. Schultz's behalf to Kansas State University. Dr. Schultz' research focuses on developing treatments to circumvent or cure cystic fibrosis. He is also studying cells that line the distal portion of the male reprod...
JCI table of contents, 2 April 2004
...e kidney that results from urine collection in the renal
pelvis or calcyses. This can lead to obstructive nephropathy, the most common form of renal
failure in infants and children. Obstructive nephropathy is often caused by structural blockage, d...
Survey reports fall in stem cell transplants for breast cancer
...e last three years of the period, primarily due to renal
cell carcinoma where there were 80 transplants in 2002. There has also been an increase in breast and lung cancers although numbers remain small. Transplant rates overall differed markedly between European countries, varying from zero in several coun...
JCI table of contents, 15 March 2004
...ely. Both diseases affect the kidney and result in renal
cystogenesis. In the March 15 issue of the Journal... in the kidneys of transgenic mice. Examination of renal
histology revealed renal
cysts in these mice. Finding a commonality in the mechanism of these diseas...
Just how much water do we really need? The answer may depend on our age
...ecreased total body water (TBW) with age, impaired renal
fluid conservation, and physiological hypodipsia or insensible thirst. Despite the physiological importance of water to life, little is known about water intake and excretion patterns in free-living individuals, because fluid intake, particularly fr...
Hopkins researchers identify transplantation antigens among Sioux Indians
...ause of a high incidence of diabetes and end-stage renal
disease, yet many are reluctant to donate a kidney... States, Leffell says. "The rate of end-stage renal
disease among Native American tribes is from 3.5 to 20 times that of Caucasian or other populations,...
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