Enzyme activation appears key in helping internal clock tell night from day
...m." The clock is literally forced back in time to repeat the necessary sequence of protein communications before it can advance. "These findings suggest that 'check-point' regulatory processes like those in the cell-division cycle, which generates two cells from one, are similar in the brain clock," said M...Brain's reward circuitry revealed in procrastinating primates
...y; even when they get rewarded they feel they must repeat the task. In mania, people will work feverishly for rewards that aren't worth the trouble to most of us."...Study by Tufts biologist provides window into progression of some degenerative diseases
...the type of unstable element called "trinucleotide repeat sequences," whose expansion causes numerous human ...pe of muscular dystrophy). There are more than 15 repeat expansion diseases, all of which are of special interest because they are caused by a highly unusual...Scientists discover new intricacies in how ulcer bugs stick to stomach
...poor sanitation significantly increase the risk of repeat infections. In addition, resistance to standard drug therapies is a major problem in these countries. H. pylori can survive in human stomachs for decades, employing many tricks to do so. To avoid being flushed out by digestive processes, the bact...Natural, man-made mix promises biggest landscape plant growth
...ppy consumer," he said, "and a happy consumer is a repeat customer." Carpio, who conducted the research for her doctoral degree, agreed on the value of doing studies that are beneficial for the public and industry. "We were expecting an improvement but somehow thought the organic fertilizer would be bette...Alzheimer's may leave some forms of memory intact
... The researchers next asked the subjects to repeat the classification task as their brains were scanned using functional magnetic resonance imaging. "What was surprising and novel in this study is that the brain region with the greatest activity during the task was the high-level region of the fronta......ts inside out, upside down and back to front, then repeat our experiments," Miller says. So what do they have to show for this effort? The researchers collected samples of calcified aneurysms (bulging blood vessels), arterial plaques and heart valves. They pulped the tissue, then filtered it to remove anyth...Moderate alcohol consumption increases plasma levels of a protective hormone
...lated to obesity. I think it would be valuable to repeat this study in a much larger population, and look at other factors which can help differentiate how alcohol impacts hormones." Rimm also suggested looking at the effects of different kinds of alcoholic beverages, such as wine and spirits. Hendriks sa...Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
...ing new approach for combating cancer. "We want to repeat the Gleevec example over and over again," says DFCI's William Sellers, MD, who with Matthew Meyerson, MD, PhD, spearheads the collaboration among investigators at Dana-Farber and the Whitehead Institute/MIT Center for Genome Research. Based at the Ma...ESA consults European science community on candidate Earth Explorer missions
...ments and a number of smaller satellites to give a repeat observation cycle of approximately three hours. One of these satellites will be EGPM flying in a Sun-synchronous near-polar orbit at 510 km altitude with two instruments on board, a microwave radiometer and a precipitation radar. Swarm a constellat...Survey reports fall in stem cell transplants for breast cancer
...t may have potential, it is critical that we don't repeat the mistake that has occurred with autologous transplants in breast cancer a premature rush to conduct large numbers of transplants based on an overly optimistic assumption of efficacy fuelled by limited clinical data. It is important to temper enth...Faulty DNA replication linked to neurological diseases
...essor in his lab, studied the sequence of a simple repeat of three nucleotides responsible for Friedreich's ...he replication of different lengths of the triplet repeat sequence, using a simple unicellular organism, yeast, as a convenient model. While yeast is far more...Aquatic scientists divided on role of sea lice from salmon farms in decline of native salmon in B.C.
...cent of the fish infected, and the farmers can not repeat this measure this year." Scott McKinley, Professor and Senior Canada Research Chair of Animal Sciences at the University of British Columbia and Executive Scientific Director of AquaNET, a National Network of Centres of Excellence in aquaculture and ...Nature and nurture in temperament
...in discipline), participants carrying any 2- or 5- repeat alleles of the DRD4 gene had a significantly greater risk of exhibiting NS scores that were above the 10th percentile on a population distribution of 2,149 adult Finnish women and men, relative to participants who were not carrying the 2- or 5-repeat...Breakthroughs lead to better understanding in prevention of transfusion-transmitted infection
...ctive individual donation samples are confirmed by repeat WNV TMA on an index or alternative sample, as well as a supplemental PCR assay and donor follow-up. A total of 296 donations (0.043%) tested WNV reactive; 212 of these donors were confirmed as WNV infected (0.031%, 1:3,215) based on det...HPV testing could be future strategy for primary screening for cervical cancer
...d examination of the cervix) or to surveillance by repeat HPV testing, cytology, and colposcopy at 12 months...y (about 6% of screened women) could be managed by repeat testing after 12 months. This approach could potentially improve detection rates of CIN2/CIN3 withou...A sweet tooth may be a 'marker' for the genetic risk for developing alcoholism
...e individuals for a period of five or 10 years and repeat the assessments," he said. "If the liking of sweets is predictive of the later development of alcoholism, then sweet likers with a positive family history of alcoholism will exhibit more drinks and/or problems related to alcohol drinking. Another a...Genetic aberration helps explain variation in cystic fibrosis
...in combinations that affect disease status. The TG repeat is typically 9 to 13 sets long, followed by a set ...n is scheduled to report that the presence of a TG repeat in CFTR that is 12 or 13 sets long is much more common in people who have 5T and a CF-causing mutati...Nerac again named one of Connecticuts fastest growing technology companies
... 56+ percent from 1998 to 2002 assisted in Nerac's repeat appearance in the Connecticut Fast 50. This year's winners averaged 172 percent growth, representing a total of $3.1 billion in revenues, over the five-year period 1998 to 2002, to the Connecticut economy. "In today's economy, double-digit percentage...New findings in yeast may reveal why growing older is the greatest carcinogen in humans
...ough the whole process," said McMurray, who had to repeat the experiment multiple times on various strains of yeast to collect enough data for analysis, resulting in many near-sleepless days and nights. "It takes a lot of practice to be able to do this kind of work under sleep-deprivation conditions," he sa...