Tag: "required" at biology news

Houston minority graduation rises in sciences, engineering as result of UH-led alliance

...ntribute 50 percent more than the one-to-one match required by NSF nationally. "The excellence workshops integral to the program are designed to develop superior problem-solving skills and are led by upper-level H-LSAMP scholars that also fosters mentoring relationships," Bear said. "Financial suppor...

Researchers determine genetic cause of Timothy syndrome

...l. "Our findings showed that the mutated region is required for inactivation of the channel, which was not previously appreciated," he said. "More broadly, this finding really highlights in a way that I haven't seen before the fundamental importance of calcium metabolism in development and physiology in human...

Newly identified master gene key in baby's first breath

...nes that stabilize surfactant production, which is required for the transition from the womb to breathing air and to protect the lungs from disease, bacterial infection and other disease and injury," Dr. Whitsett said. Foxa2 has an important role in the development of surfactant. It resides in the respi...

Evidence builds for potential new cancer drug target

... cells and in the process discovered that c-myb is required for white blood cell formation," said Reddy. In other research conducted by the team but not yet published, c-myb was deleted from breast tissue. The researchers believe that this gene plays a critical role in breast cancer and want to show the effe...

Florida Tech earns $50,000 grant to create coral database

...of corals and could eventually provide information required to detect shifting patterns of degradation and recovery at both the local and regional levels. The ability to forecast the response of reef corals to environmental conditions, as a function of natural variability and human influence, will be a key e...

A long-necked sea predator from China described in Science

...proposed a second hunting strategy that would have required participation from the pliable ribs that ran along the sides of the neck. Contraction of Dinocephalosaurus' proposed neck muscles could have rapidly straightened the neck and splayed the neck ribs outward. This could have increased throat volume enou...

Study explores gene transfer to modify underlying course of Alzheimer's disease

...CERE-110, is funding the study. Neurosurgery is required to precisely inject the drug into the nucleus basalis of Meynert on both sides of the brain. Dr. Roy Bakay, a Rush neurosurgeon and member of the Chicago Institute of Neurosurgery and Neuroresearch medical group, performs the surgery. Bakay is experi...

New anti-inflammatory strategy for cancer therapy identified by UCSD researchers

... enzyme called I-kappa-B kinase beta (IKKβ) is required for the activation of NF-kB, which acts as a master switch to turn on inflammation in response to bacterial or viral infections. In turn, NF-kB sets off a chain of reactions that lead to cancer. Mice used in the new study were given colon or ...

Chemical genetics identifies SARS inhibitors

...n targeted the helicase, and 18 targeted a protein required for virus entry into cells. The successful identification of novel small-molecule anti-viral inhibitors validates chemical genetics as a rapid and effective approach with which to tackle emerging and existing diseases. Crucially, this study has provi...

Resveratrol synthase uncovered: Cyclization specificity of type III polyketide synthases

...lated to conduct the specific cyclization reaction required to produce stilbenes? For example, stilbene synthase (STS) and chalcone synthase (CHS) share 75%90% amino acid sequence identity and generate the same tetraketide, but STS enzymes cyclize this tetraketide via an intramolecular C2 to C7 aldol condensa...

Hardy buoys: Texas A&M project predicts oil spill movements

...ing within 40 miles of the Flower Garden Banks are required by law to protect it, Guinasso notes, "so our buoys are something they very much need and want." When the nuclear submarine USS Greeneville collided with the Ehime Maru on Feb. 9, 2001, nine Japanese crewmembers were killed and the ship sank in 2,00...

A liking for sweets, combined with novelty seeking, may predict alcoholism

...ppear to be associated with alcoholism is the step required before testing them in a prospective study of individuals at risk for alcoholism to determine if these factors can indeed tell us something about who is at highest risk for alcoholism. Finally, understanding the biological/environmental bases of the...

Images of 'tail' of protein needed for cell multiplication suggest anticancer drug targets

... replication of cancer cells." The extensive study required a variety of techniques to tease apart the structure formed by the bonding of the E2 tail to E1. For example, the St. Jude team showed that deleting the tail from E2 significantly hinders the ability of E2 to transfer NEDD8 to Cul1, and blocks its ab...

The impact of genetic variations on the treatment of early rheumatoid arthritis

...ment," Dr. Criswell concludes. "Additional work is required to confirm these results," Dr. Bridges adds, acknowledging the complexity of genetic involvement in RA, "as well as to extend these observations to patients of other ethnicities, and more precisely define the individual genes and haplotypes responsib...

OutFoxed! New research may redefine late-stage cardiac development

...ls whether fusion of the bilateral heart tubes was required for later stages of development including formation of all four-heart chambers. Now we know it's not necessary". Another aspect of the work that is remarkable is that both of the hearts that form in Foxp4 mutant embryos show the same ability to dis...

Breaking new ground in germ cell guidance

...team found that maternal wun2 activity is actually required to sustain pole cells in a cell-autonomous manner: cells lacking maternal wun2 died in significantly greater numbers during migration. This suggested that wun2 had nearly opposite effects on germ cell survival depending upon whether it was expressed ...

Complex cells likely arose from combination of bacterial and extreme-microbe genomes

...ng to the report, modern eukaryotes obtained genes required to operate the cell from the bacterial side of the family, and the information-carrying genes from the Archaea side. Further, the authors say, the work also sheds light on the "horizontal" transfer of genes--sideways from organism to organism...

Sandia experiments may reduce possibility of future water wars

... after about 10 days of growth. Thus, more seed is required for the production of an equivalent amount of forage (compared to that traditionally grown in open fields), but with far less water use. The hydroponic greenhouse, also known as "protected agriculture" or "controlled-environment agriculture," als...

A new protein is discovered to play a key role in cancer progression

...) also has a key role in cancer development. It is required for the formation of a signaling complex that is an essential factor in activating TGF-b signaling necessary to suppress the growth of cancer cells. When cPML is lost, TGF-b signaling is disrupted. Primary cells from Pml-null mice are resistant to TG...

New fumigant to replace gas that damages ozone layer

...mple of a new science industry partnership that is required for successful commercialisation." The global market for methyl bromide is estimated to be more than $500 million. With the phase out of methyl bromide scheduled in 2006, organisations worldwide are racing to find suitable alternatives. CSIRO Entomo...

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