Researchers find gene for rare disorder that paralyzes children's legs
...chromosome 14 where SPG3A was already suspected to reside - samples taken from living members of the HSP-prone families, and from people with no family history of HSP. By sequencing the gene, they made a map of the DNA "letters", or nucleotides, in the specific order found in each affected and normal person...University of Pittsburgh researchers define precursors to cells that control the immune response
...rs of epidermal Langerhans cells (LCs), cells that reside in the skin and play a key role in the initiation and regulation of the immune response throughout the body. Researchers may now be able to use these cells to manipulate and control the immune response, according to the groundbreaking study to be pub...Bacteria's natural foe fights drug-resistant infections
...itional antibiotics primarily attack bacteria that reside inside cells, while the recently discovered "bacteriophage" enzymes only kill disease bacteria that lie on the surface of cells. In this study, Fischetti and his colleagues used these enzymes to eliminate Streptococcus pneumoniae present in the nasop...Hypoglycemia may affect newborn's brain cell function, says Hopkins researcher
...in cell membrane --- where the glutamate receptors reside --- the team performed assays to determine the ability of the NMDA and kainate receptors to bind glutamate labeled with tritium (3H). The researchers found that NMDA receptors from brain cells bathed in low blood sugar bound more glutamate than gluta...Sea Grant News: Caulerpa, DNA water quality detectives, Kayaking in Maine
...erested in where pathogens and indicator organisms reside in the watershed that brings the harmful creatures in contact with humans. The pathogens, such as fecal material and E.coli, travel in the watershed from one body of water to the next as they search for another host. Some pathogens do not survive t...Stem cells help brain repair, make new neurons and blood vessels after stroke
...ess. We tried to determine whether cells that reside in your bone marrow and circulate throughout the blood could turn into any of the major brain cells types, said Dr. David Hess, neurologist, stroke specialist, chairman of the MCG Department of Neurology and lead author on the study. They found in th......emories, but can access older ones that presumably reside in the cortex. Johnston and researchers in his laboratory have measured the electrical activity mediated by the NMDA receptor in the hippocampus of mutant and normal mice to help their colleagues from other institutions demonstrate that a lack of NM...Frozen 'lake' beneath Antarctica ideal to test sterile drilling techniques
...t to high-altitude clouds, and he thinks they also reside deep inside glacial ice. In fact, he will present a poster on life in solid ice at the Bioastronomy 2002 meeting in Australia during the week of July 8. Such creatures would not live in ice crystals, but in interconnected liquid veins at the boundari...Vessel reporting a weak link in national strategy to stem the flow of alien organisms to the U.S.
...res to hundreds of non-native species are known to reside in individual bays and estuaries - like Chesapeake Bay and San Francisco Bay - which are focal points for global commerce and shipping. SERC scientists have shown that the number of documented invasions continues to increase in U.S. coastal waters. ...Ulcer-causing bacteria use stomach inflammation to their advantage
...ed person's stomach, the researchers believe some reside for a time close to stomach cells, while others reside a short distance away in the film of mucus that protects stomach cells from the secreted acids in th...Subtract a gene and feasting mice add no fat
...ed for the body to make the major fatty acids that reside in fat tissue. Ntambi, who collaborated in the study with Alan Attie a professor of biochemistry at UW-Madison and Jeffrey M. Friedman, a Howard Hughes Medical Institute investigator at Rockefeller University, says the mice lacking the SCD-1 gene def...Natural-born killers enlisted to fight anthrax
...ns caused by Group A streptococcus, which normally reside in people's throats. Using a spray containing a phage enzyme specific for this bacteria, they wiped out reservoirs of this infectious bug in the throats of mice ( http://www.rockefeller.edu/pubinfo/pneumo121101.nr.php ). In December of the same year...Mayo Clinic develops blood vessel cells from adult progenitor cells
...e outgrowth cells (SOCs). SPCs produced presumably reside in the bone marrow and are stem cells that have started down the path of cell differentiation. Scientists had suspected the existence of circulating SPCs because animal studies had shown that many smooth muscle cells found in atherosclerotic plaques ...Big-bottomed sheep have a rare genetic mutation that builds muscle, not fat
...s big-bottom stature. Yet the mutation appeared to reside in a "gene desert," where no known gene had previously been mapped, said Freking. Interestingly, when they compared this sequence in the sheep to the same region of humans and mice, they found that the DNA sequences surrounding the callipyge mutation...Tiny, magnetic spheres may help overcome gene therapy hurdle
...he microspheres both could be targeted and made to reside longer in their target than the free virus. In the cell cultures, meanwhile, the researchers achieved more than 100 times the expression of the marker protein in the magnetized areas of the culture versus the others. "If you think about it in terms ...New guide helps researchers mine genome data
...or "genomic empowerment." "Interested people who reside outside the centers for studying genomes need to be told where to best view the information in a form suitable for their purposes and how to take advantage of the software that has been provided for retrieval and analysis," Dr. Varmus writes. "The ma...Sertoli cell transfer restores sperm production in infertile mice
...nerate blood cells, even though these cells, which reside in bone marrow, are relatively inaccessible to researchers. "I believe Dr. Brinster's new results have catapulted the spermatogenic stem cell system into a position of maximum experimental flexibility among all other stem cell systems in the body," s...Structure of pain-modulating enzyme described by scientists at the Scripps Research Institute
...breaks down certain fatty signaling molecules that reside in the lipid membranes of CNS cells. The TSRI group reports that FAAH modulates the action of these fatty signaling molecules through an unusual mechanism of action whereby it scoops them out of the cell membranes and chews them up. "I envision that ...Chemicals used to protect soldiers in 1991 Gulf War can damage testes, animal studies show
...s of disease. "The brain deficits we found in rats reside in specific areas of the brain that we can't measure in living humans," said Abou Donia. "This is why the deficits are so difficult to assess clinically and why animal studies are so critical to understanding the cellular damage." Complicating the d......ility to reconstitute theblood and immune systems, reside primarily in the bone marrow. However, theycan be mobilized into the circulation by cytokines, and peripheralblood-derived progenitor cells are used for the majority of hematopoieticrescue transplants. Studying the mechanism of progenitor cell mobili...