Trojan Horse Virus Controls Hiv Infection
...ets andmultiples in HIV-infected cells. Moreover, resistance to the novel VSV wouldnot be expected to develop, because that "would require loss of HIV's ability tobind CD4 or [the] coreceptor and would therefore not be selected," the authorswrite. Nava Sarver, Ph.D., chief of the targeted interventions branch ...Report Notes Difficulties In Eliminating E. Coli O157:H7 From Food Supply
...tedthat acid tolerance may increase the pathogen's resistance to other stressessuch as heat, radiation, and antimicrobials. "[E. coli O157:H7's] low infectious dose in combination with the diseaseseverity means that successful prevention strategies must focus on reducing oreliminating the presence of the microo...Bowman Gray Scientists Find Novel Way To Block AIDS Virus
...en and his colleagues set out to mimic the natural resistance of thegenetically defective individuals. They desi...n of host cells, thelymphocytes or stem cells, for resistance to HIV-1 infection, together with drugtherapy, may hold the ultimate hope for HIV treatment." ...NIDR Supports Total Genome Studies Of Major Oral Pathogens
...netic mechanisms responsiblefor virulence and drug resistance in these pathogens, and may lead to novelapproaches for preventing or eradicating infections. Actinobacillus actinomycetemcomitans The National Institute of Dental Research awarded a grant to Dr. David W. Dyerat the University of Oklahoma to deter...New Materials Remove Corrosive Gas In Coal-Gasification Process
...ased sorbents, Cal said."Carbon provides excellent resistance to chemical and physical degradationin the harsh coal-gas environment. Carbon adsorbs large quantities of hydrogensulfide, and can be used as an active support for metals -- such as copperand zinc -- which can enhance the adsorption process. And, car...New Report Sets Standard To Protect Natural Pest Control
...otection Agency's current plansto forestall insect resistance to the natural toxin Bt. To protect this natural p...s whatis needed to delay the development of insect resistance in the millions of acres already devoted to Bt corn, cotton, and potatoes. The Union of Concerned Sc......onse has been used asa tool for cloning of disease resistance genes from tomato, lettuce and rice,"said Carol Is... will only display a suicideresponse if it has the resistance genes for that bacteria. The plant hostmanufactures products encoded by resistance genes that recogn......ugs for the treatment of viral diseases, multidrug resistance in cancer,autoimmune diseases, inflammatory diseases, and neurodegenerative diseases....Cellular 'Short Circuit' Causes Insulin Resistance
...eople may explain thelink between obesity, insulin resistance and diabetes. These findings may in the future lead to new treatments for diabetesthat would be based on correcting insulin resistance. ADDITIONAL INFORMATION Prof. Zick's team included Ph.D. student Keren Paz, Dr. EytanElhanany of the Israel I...Careful Honeybee Breeding Combats Tracheal Mite Pests
...own that selectivebreeding helps honeybees develop resistance to tracheal mites, pests thatbeekeepers normally c...t OhioState. The mites eventually develop a resistance to the chemicalsanyway. We are trying to develop more natural techniques for controllingtracheal mi...Memorial Sloan-Kettering Investigators
...owly, it explains why patients withAPL may develop resistance to retinoic acid, and provides a therapy which canpotentiate the response to retinoic acid as well as prevent or overcome the lossof response to this drug. More broadly, it opens up an exciting new pathway forthe treatment of many types of cancers." ...DT104 Advice:How To Slow Salmonella Spread
...n the medical arsenal -- fluoroquinolones. DT104's resistance to specific anti-microbial drugs is one diagnostic marker(called an antibiogram or resistance profile) that is used to "fingerprint"DT104 among more than 2,000 salmonella types. Veterinarians...Washington University Licenses Its New Antibacterial Technology
...s that are less likely to besidelined by bacterial resistance than current therapies. It also provides threeyears of research funding to the Washington University scientists who areinvolved in this project. SIGA Pharmaceuticals is a New York-based drug development company thatproduces vaccines, antibio...At Life's Most Sensitive Stage, Embryos Cope With Stress
...a range of biologicalquestions, including how drug resistance evolves, which species are most likelyto be vulnerable to global climate change, and how ultraviolet light from thesun may contribute to the apparent worldwide decline in frog populations.Among the participants in the symposium were Clegg, who presen...Johns Hopkins Scientists Designing Compounds To Fight Malaria
...chonatree. But the malaria parasites began showing resistance tochloroquine nearly 40 years ago. Chinese chemists have isolated a new anti-malarial drug from theplant Artemisia annua, which has been used for thousands of yearsas an herbal remedy for fever. The drug, called artemisinin, hassince been proven to b...Induced Mutant Mouse Models Of Lipoprotein Disorders And Atherosclerosis
...n the strains in atherosclerosissusceptibility and resistance genes. Finally, the mouse atherosclerosis models are being used to examinenutritional and pharmacological effects on lesion formation and progression. Note to reporters: This is one of four fact sheets about the symposiumpresentation. New...Transplanted Neurons Restore Function In Rats After Stroke
...t USF and senior author on the study. "The grafts' resistance to theeffects of cryopreservation is rather remarkable. Frozen fetal brain cells donot survive long after they are thawed." Experimental transplantation using fetal brain cells has been successfulin a small number of patients with Parkinson's...Virulent Fungus Devastating Potato Crops
..., commonly used (on late blight) fungicide. This resistance makes suppressing the fungal epidemic more difficu...discarded. Scientists began noticing late blight's resistance to metalaxl as long ago as 1980, Fry says. The fungicide is the only way to salvage crops infected w...Link Made Between Human Growth Hormone, Bone Quality In Mice
...oorer bone quality, increased brittleness and less resistance tofractures as mice age. Steven A. Goldstein, professor of surgery in the U-M Medical School andprofessor of biomedical engineering in the U-M College of Engineering, suggestedhis results, while preliminary, raise a "red flag" on the increasing use o......noses,increased tumor formation and metastasis and resistance to chemotherapeuticagents. Naoto T. Ueno, M.D., Instructor, Gabriel N. Hortobagyi, M.D., Chairperson of theDepartment of Breast Medical Oncology, and Mien-Chie Hung, Ph.D., DeputyChairman of the Department of Tumor Biology and Director of the Breas...