Genetic variation in sensitivity to estrogen may mask endocrine disruption
...mice, known for large litters, showed a high resistance to estrogen, exhibiting only a 30 percent suppression oftestis weight even with the highest estradiol doses. Testes of several mouse strains also were examined to see if spermdevelopment and production was affected by the estradiol...First gene defect identified for precursor to adult diabetes
...rify the murky understanding of what causesinsulin resistance and diabetes. It identifies a target -- the gene'...t health hazards and its link to diabetes, insulin resistance is knownamong endocrine researchers as the "secret killer." Diabetics face a much higher than norma...Biologists predict more marine disease
...st starting to understand the mechanismsof disease resistance in marine organisms," she said. "We have identified someindicator species of heightened disease load, such as corals. The puzzle tosolve is whether corals are unusually vulnerable to disease -- due perhaps toocean warming -- or whether increased di...Genetic engineered crop studies questioned
...ncluding that the authors did not demonstrate that resistance wasactually to the same Bt toxin as in the plant o...rated considerable debate over whether the present resistance managementpolicy should be overturned." In another recent issue of Nature , a University of Arizona...Clemson's Baruch Forest Science Institute tracks forests' recovery from hurricane damage
...in September blewoff the needles and then had less resistance to cause further damage. The longleaf pine is generally not as tall as the loblolly pine so was less likely to bedamaged by the wind, although taller longleaf pines proved to be just assusceptible as other tall trees. An inventory at the res......First, that we need to explore how widespread this resistance is. Is thepercentage going to be the same in the A...probablyhigher because other mutations that confer resistance have not yet beenidentified. Viruses resistant to more than one drug were found in only 3patients, c...NSF grants provide boost to research on inner workings of plants
...ornia atDavis will examine plant genes involved in resistance to pathogens. Studies ofthe structure and function of these genes in the model plant Arabidopsis will beextended to soybean, rice and maize, allowing the development of tools formanipulation of plant disease resistance. Research at the University o...New hope for declining U.S. honeybee population
...in someregions of the United States have developed resistance to fluvalinate, as hasalready occurred in parts of...ory nature of commercialbeekeeping means that this resistance will spread rapidly to most areas of thecountry," claims Kochansky. Another compound, coumaphos, is...New drugs target HIV's deep pocket
...o drugs that interfere with the gp41 pocket, since resistance togp41 inhibitors requires that the virus be capable of varying the chemicalstructure of the pocket. The existence of the gp41 pocket was <AHREF="http://www.hhmi.org/news/keyhiv.htm">first recognized in 1997, whenWiley and Kim independently...NSF awards large grant for Arabidopsis information resource
...e plant genetics to increase productivity, bolster resistance to disease and optimize other desirable traits in the hundred or so commercially important plant species. "We will be developing a comprehensive database of Arabidopsis data with broad applications," says biologist Chris Somerville of Carnegie. "Bec...Scientists discover new candidate drugs for treating HIV infection
...lth officials are increasingly seeing strains with resistance tocurrently used drugs. Having a third line of attack against this deadly viruswould be a major advantage, says Dr. Kim. Drugs currently used to treat HIV infection fall into two categories: proteaseinhibitors that inhibit a protein called the HIV...Hutchinson Center to lead $11.5 million ovarian-cancer research consortium
... - Among women with advanceddisease, understanding resistance to chemotherapy is a key to improvingtreatment. Th...chnology,aims to identify the genes that influence resistance to chemotherapeutic agentssuch as cisplatin. Such genes would be targets for treatment strategies ai...Great increase seen in antibiotic-resistant bacteria in human colon
...ntained thegene, the new finding shows how rapidly resistance genes can spread through thebacterial population o...e genes are now moving along with the tetracycline resistance gene. Speaking at the Sixth Annual Midwest Microbial Pathogenesis Meeting inMilwaukee in September,...Jefferson scientists show drug is effective against a Hepatitis C Virus model in the laboratory
...n-toxic doses, ratherthan the virus, we think that resistance to the drugs will not be a problem,"hesays. The findings appear Oct. 12 in the Proceedings of the National Academyof Sciences. Viruses such as HCV, HBV and BVDV reproduce by actually "budding outfrom intracellular membranes." The viru...Argonne biochips may halt tuberculosis epidemic
... of other bacterial and viral diseases. Antibiotic resistance results from the natural selection of stronger bac...nt to thetreatment -- can reproduce, passing their resistance on to their offspring. In impoverished nations, where people cannot afford months of medication,vict...Monsanto's modified soya beans don't agree with the heat
...encill says that the bacterial enzyme that imparts resistance to glyphosate affects a major metabolic pathway in the plant, and has the side effect of sending lignin production "into overdrive". Gluphosinate resistance, by contrast, is achieved using a gene that simply enables plants to break down the herbicide...Genetic extremism overstates risks
... valuable changes in trees, such as faster growth, resistance to insects or benign herbicides, and controlled flowering to avoid releases of the new genes into the environment via pollen and seeds. Because they result from insertion of specific, intensively studied genes, most of the risks from this genetic m...DFG to set up 21 new collaborative research centres in 2000
...dvantages as high hardness, thermal resilience and resistance to wear and corrosion, manufacturers are currently tending to be hesitant about introducing them into practice. The scientists engaged in the collaborative research centre Highly Stressed Slip and Friction Systems based on Ceramic Engineering Materia...Targeted Genetics presents advances in synthetic gene delivery technologies
...ses, increased tumor formation and metastasis and resistance to chemotherapeutic agents. Advances in Systemic Gene Delivery Technology Dr. Anklesaria also presented data on Targeted Genetics' newest synthetic gene delivery system, designated Lipid Polycation DNA (LPD). The LPD delivery system was used ......the rare fall of rain. And that's where radiation resistance comes in handy. While radiation issues are usually associated with nuclear power or exposure to the space environment, it is not commonly recognized as being inescapable. We are exposed through our entire lives to potassium-40, radon, carbon-14 and o...