Scientists discover that metastases share a similar genetic profile to their primary tumour
...tified the ways that genetically different tumours respond to a variety of therapies. Based on the genetic profile of a patient's tumour, doctors could choose the best treatment for that particular type of tumour (from specific types of chemo-, radio- or hormonal therapies) and treat the patient with it fro...Isolated corals reefs are at risk from global climate change
...als have little of the genetic diversity needed to respond to change and appear to have no current connection to the Great Barrier Reef. The virtual absence of long-distance distance dispersal of corals to geographically isolated reefs makes them extremely vulnerable to global warming....New study confirms conservation surgery is safe for BRCA breast cancers
...of spreading to other parts of the body and do not respond to hormone treatment. "Despite the aggressiveness of these types of tumours we found after almost nine years of follow-up that there was no significant difference in recurrence between the BRCA carriers and the non-carriers with a family history or ...Combination therapy drives cancer into remission
...ral strategy for treating many cancers that do not respond to current therapies. A two-drug combination therapy, published in tomorrow's issue of the journal Nature, led to the complete remission of a mouse model of B-cell lymphoma in all of the treated animals. In contrast, animals treated with either drug...New, comprehensive tumor classification combines molecular biology and classic pathology
...eatures often follow different clinical courses or respond differently to chemotherapy." The alternative, a classification based solely on the molecular characteristics of tumors, would sacrifice the clinical/pathological experiences that inform virtually every clinical decision related to the diagnosis and ...UT Southwestern research halts narcolepsy symptoms
...use it shows that these mice retain the ability to respond to orexin," Dr. Yanagisawa said. "The downstream pathways, including the orexin receptors, are normal even in the absence of orexin-producing neurons. Also, the mice wake up, but do not try to regain that lost sleep, which is important with respect t...Gene variants may increase susceptibility to type 2 diabetes
...lin resistance--the inability of target tissues to respond to insulin--and a gradual failure of beta cells to produce enough insulin. Scientists have come a long way in understanding the basis for diseases arising from single-gene mutations. Understanding the genetic basis of the more common, polygenic d...Biochemistry and Molecular Biology: Research at the Interface of Biochemistry and Human Health
...h, with symposia on topics such as how checkpoints respond to replication perturbations, DNA replication, and...ry receptors. Since the beta adrenergic receptors respond to the hormone adrenaline, continuing research on these receptors in the Lefkowitz laboratory is con...Design of composite materials that detect terahertz discovered
...e, London have developed a class of materials that respond magnetically to terahertz radiation, a fundamental...rticularly exciting advance because materials that respond in the terahertz range have many potential applications. There are very few natural materials that ...Discoveries reveal that gene regulation is bipolar
...only a small portion of all genes--those needed to respond to emergencies--within a simple organism such as b... Pugh says. "These highly regulated genes tend to respond to acute stresses like environmental toxins, heat, and viral infection, and are often taken as repre...U Iowa study identifies damaging mechanism in transplants and heart attacks
... IkB beta in mice. Mice with only IkB beta protein respond to bacterial infection in the same way that normal mice do. However, these mice sustain less liver damage and were more likely to survive ischemic/reperfusion injury to that organ than mice with both inhibitory proteins. The study found that the two ...UW study: Baby's face lights up emotional center of new mom's brain
...ose who are dieting or have an eating disorder may respond less favorably, says the Wisconsin neuroscientist. To improve and expand upon previous studies, Nitschke and his colleagues wanted to use stimuli that evoke powerful feelings of positive emotion, such as warmth, joy and fulfillment. "There's one st...Current smoke alarms pass life-saving tests
...e alarm performance study, ionization smoke alarms respond faster to flaming fires, while photoelectric smoke alarms respond quicker to smoldering fires. The report concluded that, despite these differences, the placement of ...DFG establishes 14 new research units
...c process, plants and bacteria have receptors that respond to blue light and transform the light signals into chemical processes. How this signal processing functions has not yet been adequately clarified and is now to be examined by the Research Unit entitled "Blue Light-sensitive Photoreceptors". Humaniti...Embryonic pig cell transplants halt rat diabetes
...ird, islets are composed of mature cells unable to respond to increased need for their services by dividing and producing more cells. In contrast, embryonic pancreas cells divide readily in response to such needs, resulting in a potentially expandable source of insulin. For reasons not yet understo...Just how much water do we really need? The answer may depend on our age
...eally need? Not to swim in, or diet with. Not to respond to marketing claims, or counter salty foods or to cope with dry environments. Many swear by the advice that for proper body hydration, 64 oz of water should be consumed each day. Other scientists and researchers disagree with that long held belief...JCI table of contents, 16 February 2004
... receptor (CaR) is known to regulate how our cells respond to fluctuations in extracellular calcium levels. A report from John Wysolmerski and colleagues from Yale University in the February 16 issue of the Journal of Clinical Investigation reveals that in mice, at the transition from pregnancy to lactatio...Lactating mammary glands sense calcium
... receptor (CaR) is known to regulate how our cells respond to fluctuations in extracellular calcium levels. A report from John Wysolmerski and colleagues from Yale University in the February 16 issue of the Journal of Clinical Investigation reveals that in mice, at the transition from pregnancy to lactatio...Possible mechanism for link between diabetes and Alzheimer's disease discovered
...of the body such as muscle, liver, and fat fail to respond normally to the insulin produced by the pancreas, leading to a wide range of metabolic abnormalities. In patients with diabetes, this includes elevated blood sugar levels which, if uncontrolled, can lead to such vascular complications as blindness, ...... (FACE) experiment, is to examine how forests will respond to the increasing level of carbon dioxide in the a...indings is that young trees and other green plants respond favorably to elevated concentrations of atmospheric carbon dioxide. The relevance to the role of the...