Tag: "responds" at biology news

Calcium channels control coronary artery relaxation

...nces across the cell membrane, while the T-channel responds to a weaker "depolarization," he said. Campbell and his colleagues first became interested in exploring the T-channel because research by other scientists hinted that it might be involved in the fusion of muscle cells, or myoblasts, to one another du...

Proteins may help identify patients who will respond better to treatments in certain cancers

...h), which are known to affect the way that a tumor responds to radiotherapy. "We are using new strategies for data analysis to exploit the potential of molecular markers," said Francesca Buffa, PhD, of the Gray Cancer Institute in London. "We hope that by tailoring cancer therapy to the biological behavior ...

Mantis shrimp fluoresce to enhance signaling in the dim ocean depths

...ree visual pigments in color vision, each of which responds to light of a different color by sending signals to the brain, which recreates a richly colored world. Some stomatopods, however, have at least eight pigments sensitive to various visual wavelengths and three more sensitive to ultraviolet light. Plus...

Diet may improve cognition, slow aging, and help protect against cosmic radiation

...age-related increase in a protein (NF-kappaB) that responds to oxidative stress, a probable cause of brain aging. "Our findings fit into an emerging pattern of data from many laboratories that point to a buildup of oxidative damage as one of the key factors in brain aging," says Pilar Goyarzu, a doctoral stud...

NIH establishes Rare Diseases Clinical Research Network

...nd imaging facilities. The creation of the network responds to the Rare Disease Act of 2002, which directed NIH to support "regional centers of excellence for clinical research into, training in, and demonstration of diagnostic, prevention, control, and treatment methods for rare diseases." The term "rare (or...

Researchers define molecular basis of human 'sweet tooth'

...o transmit taste signals to the brain. Umami taste responds to amino acids such as monosodium glutamate. The r...t receptors: a combination of T1R2 and T1R3, which responds to natural and artificial sweeteners, and T1R3 which responds only to high concentrations of sugars....

UBC researcher discovers 'control room' that regulates immune responses

... immediately to test exactly how the immune system responds to a variety of pathogenic organisms, including bacteria, viruses and tumours, says Jefferies, who is a member of UBC's departments of Microbiology and Immunology, Medical Genetics and Zoology. Jefferies' research focuses on dendritic cells. A networ...

Retroviral protein triggers proliferation of immune cells

...uses adult T-cell leukemia/lymphoma, a cancer that responds poorly to treatment and that can cause death within six months of diagnosis. In others, it causes crippling and painful autoimmune-like disorders. Lairmore and a team of colleagues tested the function of p12 in both laboratory-grown lymphocytes know...

JCI table of contents, 15 October, 2003

...nt organ, except when subjected to injury, when it responds with neoproliferation of mature hepatocytes and other liver cells to the point of complete organ regeneration. There is also a contribution from resident hepatic stem cells, about which little is known. Miguel Marcos and colleagues from Universidad ...

Scientists determine identity, cell locale and quantity of nearly all proteins in an organism

...tion, and at least one phase in which the organism responds to specialized stress conditions and produces spores - sort of like abandoning ship. The scientists expect that a significant proportion of the proteins they did not identify simply are not expressed in the normal growth phase that they studied. In a...

New protein provides clue to diabetes

...in sends a signal. It is the only transporter that responds exclusively to the presence of insulin. For the study, Bogan engineered GLUT4 proteins so that they contained two distinct fluorescent tags, and studied them in cultured fat cells. One tag glowed only when GLUT4 appeared at the cell surface. The ot...

What can the genomics revolution teach us about global change?

... how an organism whether a microbe or corn plant responds to its environment. These scientists hope to understand how global warming and increased carbon dioxide affect agriculture production. "There remains great uncertainty over how crops respond to interacting environmental factors and whether new varie...

The genetics of blindness

...at make up the retina, the portion of the eye that responds to light. "Retinitis pigmentosa is a devastating and complex disease," says principal investigator, Dr. Robert Koenekoop, director of pediatric ophthalmology at the Montreal Children's Hospital of the MUHC. "Many genes, gene mutations and symptoms a...

Software tackles protein pathways

...t allow us to look at how a cell, in its entirety, responds to drugs and other kinds of stimuli. These technologies will revolutionize biology." Already, researchers like Whitehead's Rick Young are beginning to assemble libraries of cellular network pathway maps using microarrays. "But there's a problem that'...

Resistance exercise resets the body clock

...r evidence suggests that the skeletal muscle clock responds quickly to resistance exercise by regulating the transcription of specific clock genes."...

Dana-Farber researchers to lead collaborative smallpox studies

...etter understanding of how the human immune system responds to disease-causing organisms, whether they are deliberately released or naturally occurring. The Dana-Farber grant will support studies probing the body's immune response to the virus used in the current smallpox vaccine and to other viruses that may...

JCI Table of Contents

...results will help our understanding of how the BBB responds to infectious diseases and may point to a therapeutic target. TITLE: Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis AUTHOR CONTACT: Kelly Dora...

Study shows brain activity influences immune function

...g associated with affective style, or how a person responds emotionally to an event. "Emotions play an important role in modulating bodily systems that influence our health," says Davidson. "We turned to the brain to understand the mechanisms by which the mind influences the body." While earlier studies have...

Book traces the history and mystery of the Deschutes River

...to a coherent picture of how the river behaves and responds to human interventions like dams," says Grant. Grant explains that the Deschutes River possesses several unique characteristics: It has the most constant streamflow of any river of its size in the United States and behaves like a large, spring-fed...

Protein is shown to aid cell's reading of genetic code

...ly cells and studied the activation of a gene that responds to heat shock by rapidly making large amounts of protein that helps the fly adjust to heat stress. The process of gene expression is the same throughout the animal kingdom, so the work applies as much to humans as to fruit flies, Lis notes. The rese...

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