Leader in cancer treatment and prevention research honored
...his technology serves as a sensitive biomarker for response to treatment with chemopreventive agents. "Our cancer chemoprevention research laboratories are focused on research to uncover biochemical and molecular-based intervention strategies to halt and/or reverse the human carcinogenesis process," Dr. Albe...Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
...ts and natural compounds follow a bell-shaped dose response curve, which means that very low or high doses may not work and that there is an optimal dose between the two extremes." The study showed that the lycopene and vitamin E were effectively taken up in the mice prostates in the same form as they are in ...International study findings link acne-like rash to effectiveness of new targeted cancer treatment
...ients who did not develop a rash none had a tumour response and their median survival was only 2.1 months. Of the 142 with a grade one rash 8% had a tumour response and median survival was 4.9 months. Among the 141 patients who had a grade two rash the response rat...Belgian researchers explore revolutionary approach to angiogenesis
... that feed tumours have the ability to contract in response to increases in pressure within their lumen (the s...yclophosphamide to the tumour. Furthermore, tumour response to fractionated radiotherapy was also improved significantly because the increased blood flow carrie...Rare childhood genetic syndrome identified
... patients with Timothy syndrome and evaluate their response to calcium-blockers. They will also continue to look for arrhythmia genes and other calcium channels that might be involved in arrhythmia, and try to determine whether this calcium channel is involved in other forms of autism....Plants will not save us from greenhouse gases
...ll University biologist Graham Bell, looked at the response of algae to high carbon dioxide concentrations. Their findings showed that the plants could not adapt to high carbon dioxide conditions. This disproves the previous assumption that plants can take up extra carbon dioxide in the environment. According...Phase II trials of second-generation antisense cancer drug planned following successful early study
...dies are of a more conventional design, looking at response rates from OGX-011 plus standard chemotherapy in patients with metastatic hormone refractory prostate, breast and lung cancer. Phase II breast and prostate studies will begin near the end of the year, and a Phase I lung cancer trial started this mont...Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...aid, because the bacteria incite a strong "innate" response from the immune system and at the same time sneak ...he immune system -- but the strength of the immune response depends on how the flag is waved. "This immune therapy uses bacteria that induce both inflammation a...Award winning researchers reveal potential new role for Glivec
...th locally advanced disease, two achieved complete response that was pathologically confirmed through resectio...e the tumour was present and two achieved complete response confirmed by tumour assessment. Four had partial response followed by surgery to make them free of d...Researchers identify protein promoting vascular tumor growth
...ordillo said. "MCP-1 can be brought in as a repair response to help people with wounds, but it can make negative contributions to the health and well-being of people with tumors." Because angiogenesis is implicated in the development of other kinds of tumors and chronic inflammatory conditions, OS...High resolution satellite imagery assists hunt for infectious 'kissing bugs'
...ow 21 000 die every year. There is no vaccine, and response to treatment decreases with age. When first discovered in 1909, Chagas was a predominantly rural affliction, but urbanisation has brought it into towns and cities. The majority of the half a million inhabitants of Matagalpa are poor - made poorer ...Far more men than women favor routine paternity testing at birth
...omen favor such routine testing. The difference in response between genders remained consistent in spite of marital and income status. Previous studies have shown that generally less that 1 percent of married women bear children fathered by men other than their husbands. The exceptions are studies conduct...UCSF scientist Joe Derisi named MaCarthur Fellow
...ural variations in individuals' genes affect their response to drugs. DeRisi, who designs and builds microarrays -- a technology in which gene activity is revealed on a glass slide -- to carry out his studies on infectious diseases, says he plans to use the MacArthur funding to "drill deeper into mal...Florida Tech earns $50,000 grant to create coral database
... and regional levels. The ability to forecast the response of reef corals to environmental conditions, as a function of natural variability and human influence, will be a key element in the practical application of project results. Van Woesik, a noted expert on coral bleaching, has establish...Brown research reveals key insight into memory-making
... the postsynaptic cell, act like gates, opening in response to chemical messages from a neighboring neuron. During LTP, extra AMPA receptors appear, increasing synaptic strength. But where do these extra receptors come from? Michael Ehlers, associate professor of neurobiology at Duke, believed that recycling ...Scientists find nanowires capable of detecting individual viruses
...usher in a new era for diagnostics, biosafety, and response to viral outbreaks." Lieber and his colleagues merged nanowires conducting a small current with antibody receptors for certain key domains of viruses - such as agglutinin in the influenza A virus. When an individual virus came into contact with a rec...A novel, safer strategy for regulating gene expression
...e 'release' of a therapeutically useful protein in response to changing concentrations of chemicals in cells. ...whereby cells are engineered to secrete insulin in response to a rise in glucose. Such 'biological sensing' could have a wide range of applications." Current me...'Fossil genes' reveal how life sheds form and function
...king, providing a rare look at how an organism, in response to the demands of its environment, has changed its inner chemistry and lost the ability to metabolize a key sugar. The finding is a snapshot of evolution at work showing, at the most fundamental level, how traits and features are discarded by virtual...DuPont introduces in-home personal protection from dangers of hurricanes
...s. "Residents should heed the advice of emergency response professionals in the event of evacuations," said Laura Dwyer, DuPont Advanced Fiber Systems business manager. "Unfortunately, most stucco, siding or brick exteriors of homes are not designed to stop the dangerous missiles created by the high wind sp...New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
...omoting effect of the immune system's inflammatory response into a cancer-killing outcome, is suggested in res...dings provide new insight into the immune system's response to inflammation, the connection between inflammation and malignancy, and how the delicate balance be...