Tag: "response" at biology news
Scientists learn how adjuvant makes vaccines effective
...n interleukin-4, which primes B cells for a better response
to the vaccine. "Adjuvants have been included in ...give us new insight into how they boost the immune response
to a vaccine." Live vaccines, containing weakened forms of an infectious organism, generally work fi...
JCI table of contents, 15 June 2004
...Upon entry into an organism, the vaccine elicits a response
from cells in the immune system, making them targe...onic antigen, so the mice would not have an immune response
against the vaccine itself, and also human major histocompatibility genes, so that the mouse was abl...
Study helps explain island populations' susceptibility to exotic diseases
...ichness then influenced the strength of the immune response
of the hosts. The researchers tested two types of...foreign proteins, they measured the average immune response
of each island population. Finches on smaller islands with fewer parasites had a weaker immune respo...
Whole body imaging allows better understanding of the immune system
... imaging allows scientists to track how the immune response
changes, and the tumor or infection responds, throughout the different phases of immune response
and over long periods of time. At present, this exciting approach is limited to studies of very s...
Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
...esults showed a 15 percent (95% CI: 8-22%) overall response
rate in 106 patients who received Abraxane 100 mg/...rted pivotal Phase III trial demonstrated superior response
rate and time to tumor progression in metastatic breast cancer patients versus Taxol....
TIGR president discusses significance of finding anthrax toxin
...laboratory and clinical differential diagnosis and response
to naturally occurring pathogens that may resemble known bioterror agents," says Dr. Fraser. She says the TIGR/CDC study also shows how genomics can rapidly assist public health experts in responding not only to clearly identified biothreat agents, b...
Ecosystem bounces back from hurricanes
...etween hurricane floodwaters, the crabs' migration response
to the floodwaters and the subsequent overfishing ...estuary to habitats less conducive for growth. The response
of fisheries was species-dependent: There was no apparent impact of the hurricanes on commercial lan...
Two billion vulnerable to floods by 2050; number expected to double or more in two generations
...al disasters as well as regional vulnerability and response
capabilities," says Dr. Janos Bogardi, founding director of UNU-EHS. "In the warmer, wetter world predicted by science today, the northern part of the Northern Hemisphere will likely see more storms while some continental areas might have drier s...
Scientists receive awards, give lectures at the ASBMB/IUBMB meeting
... receptors that mediate the body's fight or flight response
as well as virtually all sensory receptors. His research is contributing to the development of a wide array of drugs to treat disorders including heart disease, high blood pressure, asthma and pain. The super family of seven membrane spanning recep...
Drunken worms reveal a genetic basis of alcohol response
...ior. Although the mechanisms that mediate alcohol response
in humans or other animals are not well understood, most human neuronal proteins have worm versions and it seems likely that at least some of the mechanisms are shared. Additionally, the worm has been the subject of massive genetic study by scientist...
Need sex? It's probably something about stress
...anada, is the lead author of the paper, " Sex as a response
to oxidative stress: A two-fold increase in cellul...the main method of reproduction. Instead, sex is a response
to stress. And stress generally increases the production of free radicals, sometimes called oxi...
Thimerosal, found in childhood vaccines, can increase the risk of autism-like damage in mice
...f autism spectrum disorders, including: Abnormal response
to novel environments; Behavioral impoverishment (limited range of behaviors and decreased exploration of environment); Significant abnormalities in brain architecture, affecting areas subserving emotion and cognition; Increased brain size. These...
Common worm provides insights into salmonella virulence
...archers said, because the C. elegans innate immune response
to Salmonella infection is quite similar to that of mammals, including humans. For this reason, the researchers said that their C elegans model can provide new genetic insights into the relationships between invading microbes and their target host ce...
APP reports Abraxane(TM) is active in breast cancer patients who failed taxol or taxotere
...ovided by the following findings: A 15% overall response
rate (95% CI: 8%-22%) in the 106 patients studied ...tere alone in the metastatic setting (n=33), a 24% response
rate was noted after receiving weekly ABRAXANE TM ; Of those patients who progressed while on TAXOL...
Susceptibility of mice to mousepox offers promise of smallpox protection
...and which do not. The new insights into the immune response
of mice to the mousepox virus could enable scienti...Scientists know relatively little about the immune response
to smallpox, primarily because the virus has been all but eradicated for years. Researchers and publ...
Lab mice rescued from Type 1 diabetes via dendritic cell-assisted therapy
...h of the regulatory cells that suppress the immune response
against the body's insuling-producing pancreatic i...oreign pathogens. The immune system's inflammatory response
slowly destroys the islet cells responsible for producing insulin until the entire mass of islet cel...
Carnegie Mellon U biologists identify critical player in yeast ribosome assembly
... including cell movement, metabolism, division and response
to the environment. Because ribosomes are essential for protein production, problems with their assembly inevitably spell cell death. Woolford found that changing the tail of a ribosomal protein called S14 prevented it from processing a chunk of RNA...
Obesity and hypertension: Two epidemics or one?
...onsiderable inter-individual variability in the BP response
to weight gain and not all obese individuals becom...ons for the inter-individual variability in the BP response
to weight gain remain unclear, but genetic factors may contribute. In addition, inter-individual var...
Researchers identify genetic markers to predict response to chemotherapy for colorectal cancer
...ers in the blood that can help predict a patient's response
to and side effects from irinotecan, a common chem...said. To see how genetic variations affected response
and side effects, the laboratory analyzed DNA in blood samples taken during a multi-site clinical tr...
Novel therapeutic bortezomib moves to phase II trial in lung cancer patients
...r schedule. Out of 12 patients, four had a partial response
and seven had stable disease. In the larger phase II trial, which will enroll 99 patients, the drugs will be given sequentially, with bortezomib following the chemotherapy drugs. Preclinical research at UC Davis Cancer Center suggests that giving bo...
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