Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
...the doubling time of PSA values matched the tumour responses in all the experimental groups. This means that we can use PSA values as a surrogate marker in short phase II/III human trials as it is clear that PSA values are accurately reflecting the inhibiting activity of the lycopene and vitamin E on tumour gr...International study findings link acne-like rash to effectiveness of new targeted cancer treatment
...rch. "We saw independently reviewed partial tumour responses in 12% of patients and a median survival time of 6.6 months," he said. "In total, 87% of patients developed this acne-like rash. Of the 46 patients who did not develop a rash none had a tumour response and their median survival was only 2.1 months. O...Belgian researchers explore revolutionary approach to angiogenesis
...inciple of keeping tumour arterioles open to boost responses to treatment should work in the many tumour types where ET-1 was expressed....Gladstone investigator Mike McCune wins prestigious NIH Director's Pioneer Award
...eficiency, with an eye toward understanding immune responses that might prevent the development of AIDS in HIV-... want to know if there are certain types of immune responses that protect against infection and others that might instead slow down the pace of disease," he expl...AAAS US Presidential Candidates' Forum
...ning, or reproductive cloning illegal. To read the responses of the candidates on these and other hot-button items such as Visa/Security Issues, Space Policy, Environmental Stewardship, Creationism and Energy Policy, go to: http://www.sciencemag.org/cgi/rapidpdf/1104420v1.pdf . To download Donald Kennedy's Ed...Pack-MULEs are toting a new look at plant evolution
...nce was lugging around the gene that triggers cold responses in a plant. In 1998, MSU molecular geneticist Michael Thomashow and his associate found that increasing a plant's expression of a specific regulatory gene helps throw the plant into cold-coping mode, beefing up its defenses against freezing. Her fa...Award winning researchers reveal potential new role for Glivec
...ase profiles in DFSP would correlate with clinical responses to imatinib. The ten patients were treated with 800mg of imatinib daily. Of the eight with locally advanced disease, two achieved complete response that was pathologically confirmed through resections of the regions where the tumour was present and t...Researchers identify protein promoting vascular tumor growth
... role in recruiting macrophages by observing tumor responses to an MCP-1 neutralizing antibody in mice when varying levels of macrophages were present. "Our observations specifically link MCP-1 and macrophages as key contributors to the development of these tumors. MCP-1's essential role in supporting p...Gene clusters predict atherosclerosis severity, susceptibility
...related to susceptibility tend to mediate cellular responses that occur prior to the inflammatory process. "While the methods we used to identify these genes do not have immediate clinical applications, they do play an important role in identifying genes for further study," Seo said. "The identificat...Poplar DNA code cracked -- a step in combating global warming?
...niversal biological questions. Indeed, many of the responses and functions found in plants, and thus trees as well, are also found in human and animal life. But this research can also lead to particular applications in fields such as ecology. A thorough genetic knowledge enables researchers to modify trees ge...Scientists decipher genetic code of biothreat pathogen
...plain the bacterium's ability to thwart the immune responses of its host animals mainly horses, mules and donkeys. "The combination of virulence genes and genomic instability may explain why some scientists consider this to be the ultimate bacterial pathogen," says William Nierman, the first author of the ...Brown ecologist garners major National Science Foundation grant
...nt's genes to pinpoint which ones affect flowering responses to different environmental signals, and they will study natural variants of these genes that cause these reproductive differences. The team will then create new plant lines that differ only by a single gene, allowing them to understand the role each ...K-State, other universities to study how climate affects plant evolution
...nges and how the genetic pathways underlying their responses evolve in different climates. "K-State is working ...apply the computer models that will track the gene responses in Arabidopsis plants. Working with seven leading laboratories in Europe, the researchers will plan...JCI table of contents September 15, 2004
...It remains unknown whether Cot/Tpl2 is involved in responses to other bacterial components or in the activa-tion of other immune cell types. Tetsuya Matsuguchi and colleagues examine the importance of Cot/Tpl2 in response to LPS, synthetic lipopeptide, and bacterial DNA (CpG-DNA) (pages 857866). Using RAW 264....A liking for sweets, combined with novelty seeking, may predict alcoholism
...s inability or unwillingness to inhibit behavioral responses in the face of impending punishment in alcoholics. Novelty seeking has been frequently found to be higher in alcoholics, compared with nonalcoholic control subjects, as well as in patients with a familial form of alcoholism, compared with patients...Tufts University establishes $4 million dollar tissue engineering resource center
...ssue engineering "scaffolds" to optimize stem cell responses toward new tissue formation, and designing and building novel bioreactors the apparatus for "growing" the cells and tissues that will become the products for research or clinical utility. One of the first projects will be a study of biomateria...Columbia research to examine gene influence on severity of peridontal disease, therapy response
...entify the molecular basis of the wide spectrum of responses to periodontal bacteria, and use this information ...ch will provide a wealth of data on the basic host responses to infection," said Paul Pavlidis, Ph.D., co-principal investigator of the study and assistant profe...The impact of genetic variations on the treatment of early rheumatoid arthritis
...s in the TNF gene region were found to have better responses to treatment, regardless of which drug was used. "Results of the current study suggest that, at least for RA patients with early active disease, genetic variations in the HLA and TNF gene regions are associated with response to treatment," Dr. Cris...Newborns have ear preferences, too
... data" on newborn babies' inner ear and brain wave responses to different kinds of stimuli. She and Sininger analyzed the data on infants' responses to two different kinds of 'otoacoustic emissions.' Otoacoustic emissions are sounds that are genera...Wrapping a memory with an experience, capacity for recollection detected in non-human species
...on techniques have been used to distinguish memory responses triggered by familiarity, the general sense that a person or thing has been previously perceived, from those triggered by recollection, the sudden rush of detailed memory. The BU team chose to determine whether analyses related to this technique, kn...