Bacterial Toxin Surprises Scientists
... by exactly which parts of the protein are responsible for triggering channel opening and closing. As with much scientific discovery, the study's findings raise more questions than they answer. But as they continue to study colicin Ia, the researchers hope they will improve ...Tumor Suppressor Gene Located In Liver Cancer Cells
...gical changes involved in cancer to find the genes responsible for these alterations. In this case, however, the functions of an already-identified gene led Jirtle and his team to hypothesize its involvement in liver cancer. "This is an 'old' gene for which we have characterized an important new role," Jirtle s...Second Breast Cancer Gene Located
...ted genetic mutations. "BRCA1 seems to be responsible for about half of inherited breastcancers," said Futreal, an assistant research professor of surgeryand assistant professor of genetics. "Our findings strongly suggestthat BRCA2 accounts for most of the remaining 50 percent." With the help o...Newly Discovered Bacteria Produce Magnetic Material
...tion of the atmosphere, the banded iron formations responsible forthe earth's magnetic field, and respiration in organisms." The research was supported by DOE, Office of Health and EnvironmentalResearch. ORNL, one of the Department of Energy's multiprogram national research anddevelopment facilities, is managed ...Green Glow: Not Only For Halloween
...e source of the green glow. "The unusual molecule responsible for the glow resembles a chinese finger puzzle: a barrel-shaped structure with a coil of amino acids corked in the center," explains Kamal Shukla, program director in NSF's division of molecular and cellular biosciences, which funded the research. "...Researchers Find Genetic Clues To Intestinal Disease
...rticipate in a Hopkins study to identify the genes responsible for the disease. Crohn's disease, which causes p...s disease will help researchers look for the genes responsible for the disease and help identify those at risk for developing it," says Bayless. In a related stud...Bacterial Protein Structure Hints At Mechanism Of A Class Of Premature Aging Diseases
...ing and ending at specific sites.The helicases are responsible for pulling apart the DNA strands, which aretwiste... Recently, helicase malfunction has been found responsible for a classof genetic diseases including Werner's syndrome and Cockayne's syndrome, premature aging ...Two Long-sought Diabetes Gene Found
... adolescence. In 1990, Bell mapped MODY1, the gene responsible for the disease in this family, to a small region ...pring, Bell and colleagues mapped NIDDM1, the gene responsible for a significant proportion of diabetes in Mexican-Americans, to one end of chromosome 2. In Septem...New Sensor Provides First Instant Test For Toxic E. coli Organism
.... coli bacteria. Contamination by this bacteriais responsible for recent illnesses and deaths in the United Stat... in 1982, 0157:H7 isthe virulent strain of E. coli responsible for these outbreaks. Says Stevens, "These sensors have been designed so that the presence of...Prostate Cancer May Be Predicted 10 Years Before Diagnosis
...ate cancer were diagnosed, and prostate cancer was responsible for an estimated 41,400 deaths. Prostate cancer rates are 37 percent higher for black men than white men. Between 1980 and 1990 prostate cancer incidence rates increased 65 percent, largely due to improved detection. A free fact sheet on prostate ...Bottom-up Ecological Processes Better For Clear Waters, Study Finds
...asternUnited States and Europe. Eutrophication was responsible for the dramaticdecline in water quality seen in s...f the Great Lakes during the 1960sand 1970s and is responsible for the often abysmal water clarity of urbanlakes and ponds. Lake Tahoe in the Sierra Nevada, for ex......and installation phaseof the network. USGS will be responsible for the long-term operation andmaintenance of the majority of the expanded and upgraded global network aswell as for analysis, interpretation, and dissemination of the collecteddata to help verify compliance with the treaty. The data and network wil...Prostate Cancer's Aggressiveness May Be Predicted Early By The Ratio Of Free To Total PSA
...cer will be diagnosed, and prostate cancer will be responsible for an estimated 41,800 deaths. Prostate cancer rates are 37 percent higher for black men than white men. Between 1980 and 1990 prostate cancer incidence rates increased 65 percent, largely due to improved detection. A free fact sheet on prostate gl...Purdue Researchers Prod Plants To Clean Up Pollution
...d sites after a few cropping seasons. The same DNA responsible for a plant's ability to pull toxic metals from soil could be manipulated to coerce carrot, corn, apple or rutabaga roots to reject heavy metals, Goldsbrough says. If grown in areas where soil is contaminated, such bioengineered fruits and vegetables...Munching Microbes Make A Meal Out Of Toxic Substances
.... We're trying to come up with a balance between a responsible environmental cleanup method and protecting public health, while still being cost-conscious," Nies says. Source: Loring F. Nies, (765) 494-8327; e-mail, nies@ecn.purdue.edu Writer: Amanda Siegfried, (765) 494-4709; e-mail, amanda_siegfried@un...Houseflies May Transmit Ulcer Bug
... reservoir for Helicobacter pylori , thebacterium responsible for some types of ulcers and associated withstomach cancer, say researchers from St. Elizabeth's Medical Center ofBoston in the June 1997 issue of the Journal of Clinical Microbiology . This study is the first report of H. pylori colonization of h...Scientists Bridge Gap In Cell Communication
...ghon and colleagues determined that the protein is responsible for switching genes on or off by binding directly to DNA, in effect telling the cell to start or stop a specified task. It closes the loop, said Laughon, whose work was accomplished in fruit flies taking advantage of the well-studied process...Scientists Discover How Genes Work Together To Control Neural Development
...an a search to discover exactly which proteinswere responsible for destroying Tramtrack. The researchers genetically engineered strains of fruit flies to testa number of genes whose protein products they suspected would be good candidates."There are two genetic directions you can take," Lai explains."If you wa...Where Fossils Fear To Tread: Scientists Follow Genes To An Ancient Ancestor
...d. The idea that a common set of genes is responsible for building appendages not only simplifies evolutionary history, but helps explain the great burst of evolutionary activity known as the Cambrian explosion. This "evolutionary big bang" took place in the world's oceans more than 500 million years a......ntified key regions of antigen 85proteins that are responsible for these important enzymatic activities. Now that...eate new drugsthat inhibit the enzymatic reactions responsible for keeping the cell wallintact, which will result in the death of the TB bacteria." Colorad...