Newly Discovered Human Protein Provides Important Target For Cancer Therapy
...ers in other laboratories had identified the genes responsible forproducing human telomerase RNA and one telomerase-associated human protein, butcareful studies of these genes revealed that neither could explain theregulation of telomerase activity: expression of the genes does not correlatewith observed levels ...NIH's Genbank Database Logs Billionth Base
...y and breakthroughs in health care." NCBI is also responsible for two other biomedical information systems recently in the news: PubMed and the Cancer Genome Anatomy Project (CGAP). PubMed, which provides free Web-based access to the NLM's MEDLINE database of medical literature, was demonstrated by Vice Presid...Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes
...th the X chromosome, one of two sex chromosomes responsible for sexual development. Somehow, he theorizes, the missing genes throw off normal cell proliferation and development. He believes that by getting a better handle on the mechanisms by which these genes actually can affect female developmen...Experts: Public Will Accept Irradiation In Wake Of Meat Recall
...sunderstood, but it can destroy the microorganisms responsible for food-borne illnesses and extend the shelf life of perishable foods. It is an FDA-regulated food preservation method, and currently it is allowed on foods such as spices, pork, poultry, and some fruits and vegetables. The FDA is considering approv...E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab
...heavily on it. Related strains of E. coli are also responsible for several human diseases. Although not the first bacterial genome to be completed, E. coli is by far the most complex and the most eagerly awaited by scientists around the world. "Determination of the complete inventory of the genes of orga...MGH-Led Team Finds Gene For Crippling Neurologic Disorder
... Hospital (MGH) has identified and cloned the gene responsible for early-onset dystonia, a crippling, inherited n...ective drug treatment. Only after identifying the responsible gene and then determining the function of its protein can we understand exactly how this disease pro...Pea Plant Stem Growth Gene Cloned
...ess efficient at synthesizing the gibberellic acid responsible for promoting stem growth. The plant becomes growth deficient. Gregor Mendel (1822-1884), the father of genetics, conducted experiments on the hybridization of plants, particularly peas. The results of his research were included in two lectures del...Discovery Of Genetic Pathways May Provide New Ways To Combat Candida Infections
...s of elimination, discovered the culprits that are responsible for filamentation. Once scientists identified the key yeast filamentation genes, they simply plucked out the analogous genes in Candida. "Candida albicans is three hundred million years apart evolutionarily from yeast-as far away in evolution as h...New Description Of Protein May Be Basis For Regulating Cholesterol
...ional structure of pentalenene synthase, an enzyme responsible fora key step in the formation of a natural antibiotic. The scientists also explain some of the protein's inner workings. Theysuggest that pentalenene synthase uses certain amino acids in an internalvessel-like cavity to fold, shape and transform a...Gene For Last Major Form Of Batten Disease Discovered
...the disease. The discovery of the gene and protein responsible for most cases of lateinfantile Batten disease is reported in the September 19, 1997, issue ofScience(1). The finding allows the first reliable diagnosis and carriertesting for the disease and is the first step toward developing an effectivetreatme...Photocatalytic Air Cleaning System Promises To Help Allergy Sufferers
...air," said Goswami. "Inhaled mold spores are also responsible for many allergy symptoms and aggravate asthma. Mold seeds are microscopic and need to be 100 percent destroyed. Otherwise they lie dormant and grow back. Because mold spores also circulate in the air, cleaning an environmental surface is not an effi...Disease Takes Its Toll On Waterfowl Populations
...sely related to botulism toxins A and B, which are responsible for a similar food-borne disease in humans. Affected birds lose coordination and show signs of paralysis of the legs and wings and labored breathing. In advanced stages of the disease, the birds cannot hold their heads up, and often drown or suffoc...Growth Factor Stimulation Leads To Increase In New Neurons In The Striatum And Cortex Of The Brain
... in the striatum and cortex, key areasof the brain responsible for movement, vision and higher mental functions, canbe increased in adult rats through stimulation with a growth factor, EmoryUniversity and Regeneron Pharmaceuticals, Inc. researchers report at this week's Society for Neuroscience meeting. ...Triglyceride Blood Levels Predict Heart Attack
...isk. Triglyceride levels are elevated when enzymes responsible for breaking down fatsin the bloodstream are less active. Their decreased activity results in higherVLDL and lower HDL levels, both of which are strongly associated withcardiovascular disease and heart attacks. Decreased activity might also resultin...Presence Of Protein Extends Life; Potential Aging Mechanism Found
...ch themselves would otherwise quicken themechanism responsible for aging. However, people shouldn't think they will live longer by taking daily dosesof heat or by sitting in endless saunas, Tatar said. "Our bodies tightly regulate hsp70 and other heat-shock proteins, he said."Although heat, cold and all sorts ...Gene Locus Found For Essential Tremor Disorder
...ical Disorders and Strokehave located a gene locus responsible for the most common human movementdisorder, essential tremor (ET). In an article in the November 1997 issue ofMovement Disorders, Joseph J. Higgins, M.D., Lana T. Pho, and Linda E. Nee,M.S.W., report how they traced the gene to the short arm of chro...Stress Lowers Sperm Count By Overwhelming Cells That Make Testosterone
...dy found that stress hormonesoverpower the enzymes responsible for ensuring that cells in the testes producetestosterone, which is necessary for sperm formation. Offering the first evidence that stress acts locally within the testes, via theLeydig cells, the report by Hardy and his colleagues is the lead article...Colorado State Scientists Tackle Genetic Makeup Of Obscure Bacteria
...obacterium avium. The goal is toidentify the genes responsible for allowing one strain of the bacteria tocircumvent the body's defense mechanisms and cause disease and the other strainto not cause disease and be receptive to drugs. By pinpointing what chemicalreactions or molecular processes within the bacteria ...Recombinant Protein Immunizes Mice, Promises New Strategy Against Infection And Cancer
...eins are present on the surfaceof bacteria and are responsible for flagging the T cells and triggering the CTLsto attack. Dr. Young and his colleagues found one particular protein from thetuberculosis bacterium, called hsp70, that could elicit powerful immuneresponses and could be used as an immune sys...Banning Chemicals To Protect Ozone May Aggravate Global Warming
...ssarily to global warming. "Most of the chemicals responsible for ozone depletion are alsogreenhouse gases," Wuebbles said. "Chlorofluorocarbons [CFCs],for example, tend to be severe offenders for both the depletion of ozoneand for global warming. The need for their regulation is unambiguous." But there are ...