Study Finds Gene Is Associated With Higher Risk Of One Kind of Stroke Among African-Americans
...tionof apolipoprotein-E (apo-E), a protein that is responsible for transport anddisposal of cholesterol within the central nervous system. The researchersfocused on one of the gene's three known variants, or alleles -- the one callede4. They found that in the study, blacks with a single e4 allele, inhe...Research Finds Alligator Problems Also Evident In Less Polluted Lakes
...adlines in 1993 when they said pesticides could be responsible for sexual deformities and a previous population decline of alligators in Lake Apopka near Orlando. That lake suffered from a severe pesticide spill in 1980 and commercial development on its shores. "Everyone accepted the fact that Lake Apopka had......todeplete a subset of T-cells, which are the cells responsible for cell-mediatedimmunity, the mice heal perfectly. "It is intriguing to speculate," says Dr. Heber-Katz, "that repair of woundsbecame dominant in mammals with the development of a complex immune system,which was there to protect against tumors. I..."Genetic Factors Influencing Cholesterol Response To Diet"
...ood cholesterol response to a low fat diet is that responsible for the"small, dense" subtype of LDL, also called ...different genes, but as yet the specific mutations responsible for this traithave not been identified. Non-genetic factors, such as age, body weight, anddiet, are...Induced Mutant Mouse Models Of Lipoprotein Disorders And Atherosclerosis
...This has provided insights into the genes possibly responsible for thesedisorders in humans and has allowed more invasive studies of the pathophysiologyof these disorders. The mouse as a species is highly resistant toatherosclerosis. However, several of the dislipidemias produced in the mousehave resulted in a p...Females' Siren Song Initiates Courtship Duets In African Frogs, Columbia Biologists Find
... thesecretion of male sex hormones, androgens, are responsible for establishing thenumbers and types of cells required for the vocalizations. Connections betweenmale vocal neurons and muscle fibers is weak, but strengthen with use. Dr.Tobias had demonstrated that an isolated male vocal organ can be stimulated ...Genetics May Explain Much Age-Related Hearing Loss
...g mice lacking one or both components of the genes responsible forproduction of the antioxidant enzyme superoxide...ed mice in which one orboth components of the gene responsible for production of SOD had beeneliminated, along with mice with a normal amount of SOD. "Mic...Biologists Map First Gene For Age-Related Hearing Loss In Mice
...d the vestibular canals the part of the innerear responsible for balance. Erway said the Ahl cannot be identical to the shaker orwaltzer genes, because Ahl only causes hearing loss, not abalance disorder. However, it could be an allele (a differentversion) of one of two waltzer genes found on Chromosome 10. On...Study Shows: Just Say NO To Bone Loss
...theregulation of nitric oxide synthase, the enzyme responsible for making NO; therelationship of osteoclasts to defense mechanism cells called inflammatorycytokines; and the role of transforming growth factor beta (TGF beta) in thebone resorption process. "What we really want to do is refine our understanding of...Researchers Closing In On Gene For Paralytic Disorder
...iversity of Pennsylvania havetracked down the gene responsible for a paralyzing disease that has plagued atleast ...archers report they have mapped the defective gene responsible for thisillness, a form of hereditary amyotrophic lateral sclerosis (ALS), to a sectionof chromosome...Insights Into The Proteasome - A Fascinating Macromolecular Machine For Protein Degradation
...-ubiquitin-dependent proteolytic pathway. It is responsible for the elimination of abnormal proteins, arising from mutations or damage ensuing from adverse external conditions. Moreover, it has important regulatory roles in numerous biological processes such as cell cycle, apoptosis or the immune ...Researchers From Rockefeller University Develop Novel Method To Fight Cancer
...lecule called MHC, a highly diverse set ofproteins responsible for allowing dendritic cells to communicate with T cells.MHC molecules are different in each person, giving each individual a uniqueimmune system. Even the most common MHC molecule is found in only 50 percent ofCaucasians. This requires scientists to...Virulent Fungus Devastating Potato Crops
ITHACA, N.Y. -- The fungus responsible for the Irish Potato Famine of the 1840s is back, ...ays. US-8 is more aggressive than US-1, the strain responsible for the Irish Potato Famine, which is easily controlled by metalaxyl, according to Fry. The new str...Dog Blindness Gene May Help Humans
...orrow (March 17). They say that the genetic defect responsible for progressive rod-cone degeneration (called prcd...ay form the core of the Cornell team that has been responsible for most of the research to date on theunderlying causes of canine progressive retinal atrophy (PRA)...UPMC Researchers Report On Gene Therapy Advances
...gen, an extremely strong protein found in bone, is responsible for the bonefragility seenin OI. UPMC researchers are attempting to remedy disease complications throughgene therapy in an animal model of the disease. In one study, researchersinvestigated the capacity of certain bone marrow cells to nav...Peptides Implicated In Body's Response To Pain
... found that a chemical,called neurokinin A, may be responsible for the body's response tomoderate-to-intense pain. This finding, reported in the March 26, 1998, issueof Nature(1), may eventually lead to new treatments for pain. Under the leadership of Allan I. Basbaum, Ph.D., neuroscientists at theUniversity ...Growth Factors Shown To Increase Vitamin C In The Immune System
...ng that specificglucose transporter molecules were responsible for transporting vitaminC into cells. Coupling the findings from these two lines of research, Drs. Vera, Goldeand their colleagues showed that GM-CSF increased vitamin C in target immunecells by two distinct mechanisms. The first effect was to increa...Yale Announces New Biotech Firm
...ersity's research," said Gardiner, whose office is responsible forpromoting development of Yale discoveries by the private sector. "Asidefrom creating jobs for about 70 people, the four companies are developingtechnologies that have the potential to significantly benefit human healththroughout the world." ...Molecular Defect Could Be Mysterious Cause Of Blood Disorder
...endants. The molecular defect that may be responsible for polycythemia vera wasreported by the Hopkins team recently in The New England Journal of Medicine. The finding could eventually serve as a definitive test for the disorder, whichcan be frustratingly difficult to diagnose. It also could be used a...Research Reveals Link Between Development And Contamination In Urban Watersheds
... unbiasedbasis for better decision making by those responsible for making decisionsthat affect our water resources, including the United States Congress,Federal, State, and local agencies, environmental groups, and industry.Information from the NAWQA Program also will be useful for guidingresearch, monitoring, a...