A new protein is discovered to play a key role in cancer progression
... this defect is corrected and TGF-induced activity restores normal cell functions. "The study found an unexpected role of cPML which highlights the importance of analyzing the status of PML in human cancers," said Hui-Kuan Lin, Ph.D., of the Molecular and Developmental Biology Laboratory at Memorial Sloan-...Wheelchairs biomechanics, prosthetic development
...to foot care and smoking status. Neuroprosthesis restores grasp-release hand function to individuals with SC...at least 2 seconds. The hand grasp neuroprosthesis restores grasp-release hand function to individuals with cervical spinal cord injury. A MES neuroprosthesis p...Trapping carbon in soil key for protecting global food security, dealing with climate change
...ource-poor farmers income, increases productivity, restores degraded ecosystems and improves water quality. It is truly a win-win option. "Soil carbon sequestration is a natural, cost-effective and environment-friendly process," he continued. "Once sequestered, carbon remains in the soil as long as restorativ...Jay Levy honored with 2004 Abbott Laboratories Award in Clinical and Diagnostic Immunology
... interaction of CD8+ cells with PDCs or interferon restores antiviral responses. After graduating with high honors from Wesleyan University, Levy received Fulbright and French Government fellowships to conduct research at the Universit de Paris in France. He earned his medical degree from the College of P...Biosensor-regulated gene therapy reduces heart attack damage in mice
...art attack and turns the genes off once blood flow restores adequate oxygen levels to the heart. Dr. Phillips, principal investigator; Yao Liang Tang, MD, lead author; and colleagues showed that this biosensor-regulated gene therapy protected heart muscle cells in mice with heart attacks from further injury....Combination therapy drives cancer into remission
... an Akt "effector" protein called mTOR and thereby restores the programmed cell death mechanism in Akt-positive lymphomas. The drug chosen to trigger the programmed cell death mechanism was a different antibiotic called doxorubicin. Like many traditional chemotherapy drugs, doxorubicin triggers programmed cel...Study examines whether giving good bacteria reduces infections
...e have upset the balance," says Dr. Martindale who restores the balance in patients who arrive at MCG Medical Center critically ill from sepsis following routine surgery. He first prescribes more targeted antibiotic therapy, then returns some of the primary healthy bacteria, such as lactobacillus plantarum, t...NIH consensus panel confirms effectiveness of total knee replacement
... surgery is a safe and cost-effective therapy that restores mobility and alleviates discomfort. Over 20 years of follow-up data indicate that the procedure is successful in the vast majority of patients. The panel reported that there is clear evidence of racial, ethnic, and gender disparities in the provision...JCI Table of Contents, November 3, 2003
...he health of the liver. TITLE : Stem cell factor restores hepatocyte proliferation in IL-6 knockout mice following 70% hepatectomy AUTHOR CONTACT : Lisa Colletti University of Michigan Medical Center, Ann Arbor, Michigan, USA. Phone: 734-936-7944 Fax: 734-936-5930 E-mail: colletti@umich.edu View the P...When heme attacks: After trauma, the molecule that makes life possible rampages
...hers also determined that a chemical called NS1619 restores the function of the cell membrane channel. NS1619 and its derivatives could be the source for a new drug one that prevents the secondary events that worsen trauma damage. "Following a heart attack, a stroke, or any really severe physical injury, h...New chemical process can separate, manipulate carbon nanotubes
...dles by applying heat. The thermal treatment also restores the pristine electronic structure of the nanotubes. "Until now, the consensus has been that the chemistry of a nanotube is dependent only on its diameter, with smaller tubes being less stable and more reactive," Strano said. "But that's clearly not ...New pollutant cleanup technique puzzles, pleases chemists
...pollutant have developed an approach that not only restores the power of a naturally occurring pollution buster but also boosts it to levels of effectiveness that they can't currently explain. "It's safe to say that we don't fully understand why this approach works so well, but we'll take it and develop it an...University of Rochester scientists test new method to attack cancer
...ation triggers the production of telomerase, which restores the telomeres to normal length. The restored telomeres enable the cell to divide, unchecked, thousands of times instead of the usual 50 to 100. Over time, a few cancer cells can multiply into a golf-ball-sized tumor or spread to other parts of the bo...JCI table of contents, 16 June 2003
...: Neuropeptide Y induces ischemic angiogenesis and restores function of ischemic skeletal muscles AUTHOR CONTACT: Edward W. Lee Georgetown University Medical Center, Washington, District of Columbia, USA. Phone: 202-687-1241 Fax: 202-687-7407 Email: leeew@georgetown.edu View the PDF of this article at: htt...Pathogenic yeasts and fungi: A growing health concern
...ed lactobacillus could be used as a probiotic that restores a healthy balance of intestinal microbes. The drug would thereby decrease the severity and duration of diarrhea associated with antibiotic use. In addition, he says, Saccharomyces may be employed as a vaccine delivery vector. Two other potential app...MacKinnon lab's newest picture tells action potential story
...ons to quickly flow out of the cell. This movement restores a cell's normal negative inside, positive outside charge value. The cell returns to its former calm. The entire sequence of events takes only a few milliseconds, and occurs tens of thousands of times every day in human beings and organisms of all var...New drugs restore immune response blocked by hepatitis C virus in human cells
DALLAS April 17, 2003 A new generation of drugs restores the immune response blocked by the hepatitis C vir...u block the protease, it neutralizes the virus and restores the host response to infection, allowing the cell to clear the virus naturally," said Gale. "That ty...Key to hepatitis virus persistence found
...n. "Now that we know NS3/4A inhibition essentially restores the host's immune response to the virus, we can assess hepatitis drug candidates for this ability as well," Dr. Gale says. NS3/4A will be a valuable tool in further dissecting the roles of viral proteases and their host cell targets, says Dr. Gale....A new approach holds promise for reducing cocaine craving
...r, "and treatment with n-acetyl cysteines not only restores glutamate to normal levels but also prevents glutamate levels from spiking following subsequent cocaine injections." Cocaine's effect on glutamate levels in the nucleus accumbens have been associated to cocaine addiction through the reinstatement par......operated compression belt buckled around the chest restores blood flow better than manual chest compressions a... area of the chest than manual compressions, so it restores more blood flow than manual CPR. Wherever a health care professional would do manual CPR, a device ...