JCI table of contents September 15, 2004
...ed apoptosis. In many cases the vasculature in the retina also becomes atrophied. It remains uncertain, how...inal neuronal cells. Of interest, while the mouse retina is primarily made up of rod cells, the cells that see black and white, the rescued cells after treat...Early detection hope for eye disease
A new way of taking pictures of the retina could give medics a powerful new tool in diagnosin...e filter, which allowed them to take images of the retina at a series of specific wavelengths. The images are captured by a sophisticated digital camera - a ...New clues to hereditary blinding disease found
...k down, triggering cell death, degeneration of the retina and eventually blindness," said John Hwa, MD, PhD, assistant professor of pharmacology and toxicology at Dartmouth Medical School. "What is especially exciting about this new direction in our research is that this characteristic of rhodopsin is very...Scientists identify cells that lead to retinoblastoma
... Rb, the scientists knocked out the Rb gene in the retina of mice. Expecting to see the cells with defective Rb die as a result of cell death, they were instead surprised to find that while four types of cells did die, three type of cells not only survived but also continued dividing. "Just like tumours, th...New laboratory model can be used to test new treatments for pediatric eye cancer
...tumor suppressor genes are only knocked out in the retina of the developing embryo, which is exactly what happens in children with retinoblastoma. As a result of confining the mutation to the developing retina, the mice do not develop other types of cancer and can be bred to pass on the genetic mutations. T...Bird's eye views earth's magnetic lines
...ield is sensed by light-absorbing molecules in the retina of a bird's' eye. Thorsten Ritz, a postdoctoral associate in the Phillips' lab at Virginia Tech who is now a faculty member in the Department of Physics and Astronomy at the University of California, Irvine, co-authored the paper with Peter Thalau o...Brace therapy for osteoarthrisis, legal issues in TBI research, prosthetic fitting
...tudied 15 rabbit eyes to determine how quickly the retina recovers following surgical implantation of a pros...consider a temporary, below-normal response of the retina to surgery and stimulation could lead to a false conclusion that an implanted prosthesis is not adeq...Biological cause of one form of blindness identified by SLU researchers
...as the capillaries beneath the eye, and not in the retina itself; typically, genes involved in retinal disea...a secretory protein in the capillaries beneath the retina to improperly "fold," a process necessary for healthy cell development. When the proteins fail to fo...Cellular problems found behind complex obesity syndrome
...ation of the two proteins in specific cells in the retina and in certain brain cells, as well as small areas of other tissues," Katsanis says, describing the team's analysis of tissues from mice and mouse embryos. Based solely on where the two proteins are found in mice, Katsanis can suggest a few reas...Too good eyes for living below ground
...an African mole-rats have a rather well-structured retina with an unusually high proportion of cone photorec...ies fit the concept of a general regression of the retina in adaptation to a lightless living environment. Evolutionary biology would predict that obsolete st...Scientist works to interrupt early changes resulting in diabetic vision loss
...s the sight of diabetics, vital nerve cells in the retina begin to die. The dying cells have a characteristi... of events that disrupts the beautifully organized retina over years; eventually, this back portion of the eye begins to grow new blood vessels, presumably in...Rb protein's role in retina development is key to understanding devastating eye cancer
...Rb is required for proper development of the mouse retina is a major step toward understanding why some chil...the proliferation of immature retinal cells so the retina develops to a normal size. The Rb protein also prompts specific cells to develop into light-sensitiv...New systems biology center positions UT Southwestern in vanguard of scientific research
...ystems biology can address. Photoreceptors in the retina convert light into electrical signals, which then pass into the brain where they are interpreted, resulting in vision. Proteins within these cells are responsible for that conversion of light into electrical signals. Researchers have identified 50 to...EMBL researchers discover key molecular 'switch' in eye development of medaka fish
... medaka embryos. SIX3 helps cells develop into the retina and part of the brain. "This protein is so powerfu...l produces it at the wrong stage of development, a retina will form even if it's in the wrong place in the body," Wittbrodt says. Del Bene discovered that SI...Imaging technique reveals new structure in retinal cells
...e technique allowed the researchers to examine the retina tissue within the eye without damaging it. After ...hnique will continue to boost understanding of the retina and the retinoid cycle. Since many types of congenital blindness are caused by defects in the retino...Stem cells found in adults may repair nerves
...e in the spinal column can create new cells in the retina of the eye, especially in young animals of some species, according to Reh. The retina is a delicate light-sensitive membrane that transmits light signals to the brain. Many eyes diseases...Key advance reported in regenerating nerve fibers
...the optic nerve, which connects nerve cells in the retina with visual centers in the brain, but the Children's team has already begun to extend the approach to nerves damaged by spinal cord injury, stroke, and certain neurodegenerative diseases. Results appear in the February 18th Journal of Neuroscience. ...New standard on the menu, certified slurried spinach
...n, skin and hair. Lutein is a pigment found in the retina and may help guard against eye diseases such as age-related macular degeneration. Among its other attributes, spinach also contains 1.55 percent dietary fiber by weight. The new SRM was developed at the request of the food industry and with the help ...Cells' ability to open blood's floodgates hinges on unexpected factors
...w paper, the same effects were detected in the rat retina and visual region of the brain during optical stimulation. Williamson and his co-authors have also revealed that the increased NADH/NAD ratio activates a signaling pathway that promotes the creation of nitric oxide, a compound widely recognized for i...OXiGENE launches significant expansion of its R&D program in ophthalmology
...e to grow; rather, they stretch and thin out. The retina and Bruch's membrane (the tissue behind the retina that separates it from the blood vessels of the choroids) are two of the tissues that stretch and be...