Tag: "retinoic" at biology news
Arsenic Shown To Induce Cancer Remission
...essful form of treatment -- adrug called all-trans retinoic
acid that was also pioneered by Dr. Warrell. Several years ago, he and others showed that all-trans retinoic
acid could beused with chemotherapy to treat many patients with APL because it forced cancercells to...
Wistar Scientists Locate Genes Involved In Mammalian Tissue Regeneration
...s, or region, one potential gene is a receptor for retinoic
acid, known toplay a role in developmental processes and the growth of skin. Interestingly,retinoic acid is also involved in amphibian regeneration. Similar to what has been seen in amphibian regeneration, "healer" mice appear todevelop a blastema a...
Clinical Trials Show That Bone Marrow Transplant And Vitamin A Derivative Both Improve Survival From Neuroblastoma
...transplant and follow-uptherapy with high doses of retinoic
acid, a derivative of Vitamin A --significantly im...ree years after beginning follow-up treatment with retinoic
acid. Thatrate compares to 16% for children treated with consolidation chemotherapy alone. Neurobla...
Retinoic Acid Used In Cancer Treatment
...sion that leads to cancer. The chemical is retinoic
acid, a product of vitamin A, which the body manuf...ncers, including leukemia, that seem to respond to retinoic
acid. The research also highlights the cancer-prevention role of carotenes. "This is one mo...
Transplanted Neurons Restore Function In Rats After Stroke
...an embryonal cancer cell line that was treatedwith retinoic
acid in a process to differentiate the cells and t...emoved from acancerous human tumor. Treatment with retinoic
acid altered the cells so thatthey became noncancerous and differentiated to take on the characteris...
Hormone Control Of Rare Leukemia Sheds Light On Molecular Basis Of Cancer
...necalled PML on chromosome 15 and the gene for the retinoic
acid receptor (RAR) onchromosome 17. In another 4 ... called PLZF. "The involvement of the retinoic
acid receptor in both forms of APL iskey to understanding the complex genetics of this disease," say...
Memorial Sloan-Kettering Investigators
.... Raymond P. Warrell, Jr. showed that adrug called retinoic
acid (RA) could be used to treat many patients wit...F-RAR they were insensitive to RA, explaining why retinoic
acidworks in some APL patients but not others. Armed with this new knowledge, the MSKCC rese...