New Study Shows Steps Leading To Colon Cancer
... "Our work, together with that of our colleagues, reveals for the first time the precise role of a key regulatory protein found in both insects and ourselves," said Dr. Mark Peifer, assistant professor of biology at the University of North Carolina at Chapel Hill. "We have found that this protein, called 'a...Scientists Bridge Gap In Cell Communication
...new genetic-based treatments for disease. It also reveals that the pathway from cell surface to the gene is remarkably direct. CONTACTS: Allen Laughon , (608) 262-2456, alaughon@facstaff.wisc.edu ; Sean Carroll , (608) 262-6191, sbcarrol@facstaff.wisc.edu...Discovery Of Genetic Pathways May Provide New Ways To Combat Candida Infections
...f the Whitehead Institute for Biomedical Research, reveals that one key to Candida's infectiousness lies in its ability to switch from a rounded form to filamentous forms. When the wiring diagram underlying this switch is inactivated, Candida infections are no longer deadly in mice. The implications of thes...Imaging Studies Illuminate Brain's Response To Cocaine
...report,appearing in the September issue of Neuron, reveals that a much broader range ofbrain structures is involved in the cocaine "rush" than previously suspected andthat the role of brain areas long thought to be involved in making cocainerewarding and addictive is more complex than previously believed. "...SFU Researcher Fools Forest Pest Into 'Barking Up The Wrong Tree'
...n detect the scent of host trees. But Huber's work reveals that the beetles are doing much more. They're smelling other trees in the forest, too. Every type of tree, says Huber, releases signature compounds, or 'volatiles,' into the air. And just as we can smell the fragrance of a nearby pine or fir, abark b......roms)electron density map of the complex. The map reveals the nucleic acid-bindingsite, as well as the previously described ATP-binding site that drives theenzyme's activity, amid three distinct structural domains of the NS3 helicase. The structure yields important clues regarding the mechanism by which hel......of thetheory that birds evolved from dinosaurs and reveals an advanced stage in thistransition. Numerous physical characteristics in the fossil skulls show thatthese strange creatures were actually early birds, challenging the traditionalview that all primitive birds looked similar to their modern-day cousi...Three-Dimensional Structure Of Human Lung Tryptase Determined, An Enzyme Involved In Allergic Asthma
...nd W. Bode, Nature 392, 306) on March 19, 1998, reveals four quasi-equivalent monomers arranged in a square flat ring. Each monomer contacts its neighbours at two different interfaces via six loop segments. These loops are located around the active site and differ considerably in length and co...Caribbean Lizards Evolve Independently
...tionary history of the Anoles. The study reveals a perfect example of an evolutionary concept known as"convergence", where species evolve in similar adaptations to the environmentdespite living geographically apart. Although evolutionary convergence has beentaken as evidence for the working of nat...... size="3" face="Symbol"> This structure reveals some topological similarities with the catalytic domain of a snake venom metalloproteinase previously elucidated by the same Martinsried group, with a number of large polypeptide insertion loops generating unique features at the molecular...Despite Odds, Little Known Grauer's Gorillas Persist In Central Africa
...published in thecurrent issue of the journal Oryx, reveals that the population ofthese mysterious primates has remained surprisingly stabledespite growing human pressures. Conservationists warn,however, that local populations have become increasinglythreatened due to political instability, hunting and defore...False Security: You Can't Always Believe The Results Of A Genetic Test
...erican Journal of Human Genetics (vol 62, p 1252), reveals a disturbing picture. The investigators asked 45 labs how many mutationsin the cystic fibrosis gene they usually test for. Forty-three responded, reporting numbers ranging from just one to 70. It was most common to test for between 12 and 14 mutation...Crystal Structure Of Key HIV Protein Reveals New Treatment Targets
...he new model of the gp120 core's crystal structure reveals specific targets foranti-HIV vaccines and drugs, and highlights the surprising array of defensesthat the virus uses to evade attack. "Studying the gp120 crystal's structure can tell us a lot more about how thevirus locks on to immune system cells,"...Largest Generation Of Adolescents Faces Reproductive Health Risks
...es: A Global Review An article by Susheela Singh reveals that as the number of years that youngwomen spend unmarried increases, the possibility of premarital sexual activityand pregnancy rises. As a consequence, in several countries, particularly insub-Saharan Africa (for example, in Botswana, Kenya, Liber...Syphilis Genome Sequence Offers Clues To Better Diagnosis, Prevention And Treatment
...ing countries. The genome sequence for T. pallidum reveals the existence of 12 membrane(surface) proteins that could be tested in experimental vaccines. One or moreof these surface components might stimulate the immune system to respond to aninvasion of T. pallidum when an uninfected person is exposed to sy...Biologist Wins Simon Fraser University Controversy Prize For 'Silent Spring' Of The '90s
...ontrol decisions. In the process, Winston reveals a consistent pattern of misinformationand mistakes - on both sides of the debate - and calls for a more enlightenedapproach to pests, one based on management rather than eradication. He also proposes a new pest management ethic that favors b...Study 'Gone With The Wind' Provides Stellar Ecological Example
...se intoa completely different one that graphically reveals how natural forcesperiodically play with an ecosystem's populations and tip the so-called "balanceof nature." Jonathan Losos, Ph.D., associate professor of biology at WashingtonUniversity in St. Louis, and biologists David A. Spiller and Thom...Scientists Discover New Players On The Gene-Activation Team
...described as "provocative and highly significant," reveals moleculespreviously unknown to be involved in gene...roup that made the discoveries. Workman's research reveals new players on the team of molecules thatturns on a gene--a precise section of DNA containing one of...Structure Of Enzyme Involved In Gentamicin Resistance Revealed For First Time
...Our structure of this antibiotic-resistance enzyme reveals how remarkablysimple proteins can present life-threatening problems for critically illpatients," says senior author Stephen K. Burley, M.D., D.Phil., Richard M. andIsabel P. Furlaud Professor and head of the Laboratory of Molecular Biophysicsat Rocke...Subterranean Mapping Method Will Find Homes For Pollution-Eating Bacteria
...ubsurface. A cross-section of the Virginian soil reveals orange streaks of iron oxidelayered between light-colored sand. Smith said they chose Oyster because "theground is very, very simple there. If we can't do it at a simple site, we can'tdo it at a more complex one." But trips out to Virginia's east...